General information for g4122.t21
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aldehyde dehydrogenase, mitochondrial.
Parent gene
- The parent gene g4122 is located on chr_3: 30744881..30746107 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g4122 | g4122.t21 | TTS | g4122.t21 | 30743782 | 30743782 |
| chr_3 | g4122 | g4122.t21 | isoform | g4122.t21 | 30744529 | 30745693 |
| chr_3 | g4122 | g4122.t21 | exon | g4122.t21.exon1 | 30744529 | 30744541 |
| chr_3 | g4122 | g4122.t21 | cds | g4122.t21.CDS1 | 30744531 | 30744541 |
| chr_3 | g4122 | g4122.t21 | exon | g4122.t21.exon2 | 30744597 | 30744635 |
| chr_3 | g4122 | g4122.t21 | cds | g4122.t21.CDS2 | 30744597 | 30744635 |
| chr_3 | g4122 | g4122.t21 | exon | g4122.t21.exon3 | 30744726 | 30745144 |
| chr_3 | g4122 | g4122.t21 | cds | g4122.t21.CDS3 | 30744726 | 30745144 |
| chr_3 | g4122 | g4122.t21 | exon | g4122.t21.exon4 | 30745203 | 30745319 |
| chr_3 | g4122 | g4122.t21 | cds | g4122.t21.CDS4 | 30745203 | 30745319 |
| chr_3 | g4122 | g4122.t21 | exon | g4122.t21.exon5 | 30745375 | 30745545 |
| chr_3 | g4122 | g4122.t21 | cds | g4122.t21.CDS5 | 30745375 | 30745545 |
| chr_3 | g4122 | g4122.t21 | exon | g4122.t21.exon6 | 30745647 | 30745693 |
| chr_3 | g4122 | g4122.t21 | cds | g4122.t21.CDS6 | 30745647 | 30745693 |
| chr_3 | g4122 | g4122.t21 | TSS | g4122.t21 | 30745933 | 30745933 |
Sequences
>g4122.t21 Gene=g4122 Length=806
ATGGAAACTCCAAAAAATCCTAATCCAAATCCAGATCAAGAAATTCATAAAAAGACTTTT
GCTACAATTAACCCAGCAAATGGCAAAAAAATCGCTGACATCGCTGAAGCTGATAAGGCT
GATGTCGATTTAGCAGTTAAAGCTGCACAAAAAGCATTCGAACGTGGCTCTGAATGGCGA
AATTTAGATGCTTCAGCTCGTGGAAGATTACTTTATCGTTTAGCGGACCTAATTGACCGT
GATTCAGCTATTCTCTCCAATTTGGAAACATTAGACAATGGAAAACCTTATGAAGATGCA
TGTCTGGATGTTTTGTTTAGTGGTGAATTTTTACGTTATTATGCGGGATTATGTGACAAA
ATTCATGGCAGAACTGTTCCAAGTGATGGCAATCTTTTTAGTTATGTTCGCAAAGAACCA
ATTGGTGTAGTAGGCCAAATTATACCTTGGAATTATCCTCTTATGATGGTAAGCTGGAAA
TGGGCACCGGCTTTAGCTGCTGGATGCACAATAGTACTTAAACCAGCAGAACAAACTCCC
CTTTCGGCTTTATATGTCGCAAATCTCGCGAAAGAAGCGGGTTTTCCTGCTGGCGTAGTT
AACGTAATTACTGGCTATGGGCCAACTGTTGGTGCCGCTATTGCATCACATCCTGATATT
CGCAAGGTTGCATTTACAGGCTCAACTGAAGTTGGAAAATTAATTATGGAAGCTGCTGCA
AAATCAAATTTGAAGAAAGTTTCATTAGAGTTGGGTGGCAAGAGTCCTCTCGTCATCTTT
GATGACGTAAACATTGATGAAGCAGT
>g4122.t21 Gene=g4122 Length=268
METPKNPNPNPDQEIHKKTFATINPANGKKIADIAEADKADVDLAVKAAQKAFERGSEWR
NLDASARGRLLYRLADLIDRDSAILSNLETLDNGKPYEDACLDVLFSGEFLRYYAGLCDK
IHGRTVPSDGNLFSYVRKEPIGVVGQIIPWNYPLMMVSWKWAPALAAGCTIVLKPAEQTP
LSALYVANLAKEAGFPAGVVNVITGYGPTVGAAIASHPDIRKVAFTGSTEVGKLIMEAAA
KSNLKKVSLELGGKSPLVIFDDVNIDEA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g4122.t21 | Gene3D | G3DSA:3.40.605.10 | Aldehyde Dehydrogenase; Chain A | 9 | 268 | 5.8E-116 |
| 2 | g4122.t21 | PANTHER | PTHR11699:SF269 | ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL-LIKE PROTEIN | 16 | 268 | 5.8E-135 |
| 3 | g4122.t21 | PANTHER | PTHR11699 | ALDEHYDE DEHYDROGENASE-RELATED | 16 | 268 | 5.8E-135 |
| 1 | g4122.t21 | Pfam | PF00171 | Aldehyde dehydrogenase family | 17 | 268 | 5.6E-98 |
| 5 | g4122.t21 | ProSitePatterns | PS00687 | Aldehyde dehydrogenases glutamic acid active site. | 249 | 256 | - |
| 4 | g4122.t21 | SUPERFAMILY | SSF53720 | ALDH-like | 16 | 268 | 3.53E-95 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
