General information for g423.t6
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Acetyl-CoA acetyltransferase B, mitochondrial.
Parent gene
- The parent gene g423 is located on chr_3: 3310625..3312206 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g423 | g423.t6 | TSS | g423.t6 | 3308254 | 3308254 |
| chr_3 | g423 | g423.t6 | isoform | g423.t6 | 3308813 | 3310625 |
| chr_3 | g423 | g423.t6 | exon | g423.t6.exon1 | 3308813 | 3309280 |
| chr_3 | g423 | g423.t6 | cds | g423.t6.CDS1 | 3308884 | 3309280 |
| chr_3 | g423 | g423.t6 | exon | g423.t6.exon2 | 3309870 | 3310179 |
| chr_3 | g423 | g423.t6 | cds | g423.t6.CDS2 | 3309870 | 3310179 |
| chr_3 | g423 | g423.t6 | exon | g423.t6.exon3 | 3310340 | 3310625 |
| chr_3 | g423 | g423.t6 | cds | g423.t6.CDS3 | 3310340 | 3310625 |
| chr_3 | g423 | g423.t6 | TTS | g423.t6 | 3310652 | 3310652 |
Sequences
>g423.t6 Gene=g423 Length=1064
CCTATGGTGGAGTGAATTTAATTGATGGCATTGTTCATGATGGTTTATGGGATCCATATA
ACAAATTTCACATGGGTAATTGTGCTGAAAATACAGCAAAAAAACTTGGAATTACAAGAC
AGCAACAAGATGAATATGGAATTTCAAGCTACAAACGATCAGCTGAAGCATGGAAAAATA
AAATTTTTGATGCAGAAATCACACAAGTTTCAATTCCACAAAAGAAAGGCAAACCTGATA
TTGTAATTACAGAAGATGAGGAATATAAAAGAGTTAATTTTGATAAATTTGGCAGCTTGG
GAACAGTCTTTCAAAAAGAAAATGGAACAGTTACTGCTGGTAATGCAAGTACATTAAATG
ATGGTGGAGCAGCTTTAGTCCTAATGACAGCTGAAGCTGCAGAAAAACATAAATGTAAAC
CACTCGCTCAAGTTGTTGGCTTTGCTGATGCTGAAACTGATCCTATTGATTTCCCAATTG
CACCAGCAAAAGCAGTACCAAAATTATTGGAACAAACAGGTGTGAGAAAACAAGATGTTT
CATTGTGGGAAGTGAATGAAGCATTTTCACTTGTTGTGTTAGCAAACATGAAATTAATGG
ATTTGGATATAAAAAATGTAAATATTCATGGCGGAGCTGTTAGTCTTGGCCACCCTATTG
GGATGTCGGGAGCTCGCATAGTAGTACATCTTCTTCACAATTTGAAACAGGGACAGTATG
GTTGTGCATCAATTTGCAATGGTGGCGGAGGTGCATCATCAATTATGATTCAGAAATTAC
ATGATGAAAAATCAAGTGACTTGCCAACAATAACTCTTTATACACATGATCATTGTTCAT
TATGTGATGAGCTTGTGAATGAATTAGAAGGAAAATTTAGTGGACGTTATCGATTGGAGA
AAATTGACATTACAAAGAAAGAAAATTTAAAATATCTTCGATTATATCGACTTGATATTC
CTGTATGCTTCCTAAATGGTCAATTTCTTTGTATGCATAAATTAAATAGTAGTCTATTAG
AAAAAAGATTAAACGAAATTGAAGAAACAAATTCATCGAAATAA
>g423.t6 Gene=g423 Length=330
MGNCAENTAKKLGITRQQQDEYGISSYKRSAEAWKNKIFDAEITQVSIPQKKGKPDIVIT
EDEEYKRVNFDKFGSLGTVFQKENGTVTAGNASTLNDGGAALVLMTAEAAEKHKCKPLAQ
VVGFADAETDPIDFPIAPAKAVPKLLEQTGVRKQDVSLWEVNEAFSLVVLANMKLMDLDI
KNVNIHGGAVSLGHPIGMSGARIVVHLLHNLKQGQYGCASICNGGGGASSIMIQKLHDEK
SSDLPTITLYTHDHCSLCDELVNELEGKFSGRYRLEKIDITKKENLKYLRLYRLDIPVCF
LNGQFLCMHKLNSSLLEKRLNEIEETNSSK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g423.t6 | CDD | cd00751 | thiolase | 1 | 235 | 1.7131E-114 |
| 10 | g423.t6 | Gene3D | G3DSA:3.40.47.10 | - | 1 | 236 | 1.2E-86 |
| 11 | g423.t6 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 244 | 322 | 2.4E-18 |
| 4 | g423.t6 | PANTHER | PTHR18919:SF156 | ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL | 1 | 236 | 1.7E-122 |
| 5 | g423.t6 | PANTHER | PTHR18919 | ACETYL-COA C-ACYLTRANSFERASE | 1 | 236 | 1.7E-122 |
| 2 | g423.t6 | Pfam | PF00108 | Thiolase, N-terminal domain | 1 | 107 | 1.1E-32 |
| 1 | g423.t6 | Pfam | PF02803 | Thiolase, C-terminal domain | 116 | 235 | 1.6E-42 |
| 3 | g423.t6 | Pfam | PF05768 | Glutaredoxin-like domain (DUF836) | 246 | 320 | 3.0E-11 |
| 9 | g423.t6 | ProSitePatterns | PS00737 | Thiolases signature 2. | 184 | 200 | - |
| 7 | g423.t6 | SUPERFAMILY | SSF53901 | Thiolase-like | 1 | 114 | 4.82E-24 |
| 6 | g423.t6 | SUPERFAMILY | SSF53901 | Thiolase-like | 114 | 233 | 4.03E-35 |
| 8 | g423.t6 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 241 | 323 | 1.49E-12 |
| 12 | g423.t6 | TIGRFAM | TIGR01930 | AcCoA-C-Actrans: acetyl-CoA C-acyltransferase | 1 | 233 | 4.0E-82 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016746 | acyltransferase activity | MF |
| GO:0016747 | acyltransferase activity, transferring groups other than amino-acyl groups | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
