General information for g427.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Aladin.
Parent gene
- The parent gene g427 is located on chr_3: 3318881..3319484 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g427 | g427.t1 | TTS | g427.t1 | 3317960 | 3317960 |
| chr_3 | g427 | g427.t1 | isoform | g427.t1 | 3318006 | 3319484 |
| chr_3 | g427 | g427.t1 | exon | g427.t1.exon1 | 3318006 | 3319316 |
| chr_3 | g427 | g427.t1 | cds | g427.t1.CDS1 | 3318006 | 3319316 |
| chr_3 | g427 | g427.t1 | exon | g427.t1.exon2 | 3319371 | 3319484 |
| chr_3 | g427 | g427.t1 | cds | g427.t1.CDS2 | 3319371 | 3319484 |
| chr_3 | g427 | g427.t1 | TSS | g427.t1 | 3319540 | 3319540 |
Sequences
>g427.t1 Gene=g427 Length=1425
ATGGCTTCATTAAGAAGTTTTAGCGGTTCTGTTCTTCCAGGAGATTCAACATTTCACGAA
GGAACATCAAAAGTTTGTTCTCTACCACAAAAATATACGACAAATTCAGTAAAAATTAAT
TCGTATCCGGAGATCAATATTAGCAGAGAAATCTATAATTCGCACATTTCAAGGCAAGAT
CATCTAATATTGCCAGTACAAGAACCGTTTGTGAAACAATTAGCAAGAACTTTTTTCGAT
GAAGGAGTTAAATCTTCACTTAATCTTCTCAAAGATTCAAATCTTAGTCTTTTCTCACAA
CTATCAAATGGAATTCTTAAAATAATGAATTATGGCAATCGCATTAAAATGTTTTTCAAT
CCACATCTACGTGAAATTGGTATTGAAAATTATGAAAACTTTTCGCAAGTTCGTCAATGG
AAAAATGCAACTGTGAGATTTCTAGCATTTCATCCGCAATGCTTTAAAATTGCTATAGCT
AGTGTTGATGATACAATAAGAATCTACACAAATGATGAAAATTCGATTGTGCCATTACTC
AAAAATTCACAGCAAAAATCAATTTTTACACTTGCATGGCGACCTTTTTCTCCTTCAACT
CTTGTTGTCGGTTGCCAAAATGGAATTTTAATTTGGACCATAGATCCAAGTTCGAATATA
AGTCGCCCACTATCTTCAGCAGTACATTATCGTCATGAAAATCATTTTCCAGTCACTTCT
GTTGAATTTAATCACAATGGAAGTCTTTTAGCGACTGCAAGTTTAAAAGATACATCGATT
TTAATATGGAATATTGATAAAATGTCTTGTACACCACTAAAAAAGACTTCAATTCCTTTT
CTTAATTTGCAATGGAGCATGAATGGATCATATATTTTTACATCAACTGTGGGAAATGTA
TTTCGTGTTTGGAATTGTGACACTTGGAAATCTGATAGATGGACTGTTGCAAATGGTCAT
GTGCAATCATTTCAATGGTCACCATGTGGAAAGTTTTTGCTTTTTGTAACATCTGAAGAT
CCTGTTTTATACTCATTAGGTTTTGCTGATGAACCAATTTTCAATGAGAATTCAAAGAAA
ATTCAGCAACCACAAAGAGCTCTTCCTGTTGCTGACCTTTCACAAATTGAAATTGAACAC
TCTGAGTTGGGAGGTGTTGCTCAACAATTAGCTTGGAATGGAAAATATTTAGGCGTTTCA
TTTAAAACAACAAATTCAATTGCAATCTTTCAAACTACCATTCGTCAACATCAACTTCAT
ATTTTACCAATGTTTTTTATCAATGGAATGGGAACAGAATTTCCAACATTCATCACTTTT
CAACCATCTTACAAGAATTCATTATCGCATAGAGCTGAAAATGTTTTAACAATTGCATGG
TCAAGTGGAAGAATTGAATTTTATTCAAATAATTTGTTTAATTAA
>g427.t1 Gene=g427 Length=474
MASLRSFSGSVLPGDSTFHEGTSKVCSLPQKYTTNSVKINSYPEINISREIYNSHISRQD
HLILPVQEPFVKQLARTFFDEGVKSSLNLLKDSNLSLFSQLSNGILKIMNYGNRIKMFFN
PHLREIGIENYENFSQVRQWKNATVRFLAFHPQCFKIAIASVDDTIRIYTNDENSIVPLL
KNSQQKSIFTLAWRPFSPSTLVVGCQNGILIWTIDPSSNISRPLSSAVHYRHENHFPVTS
VEFNHNGSLLATASLKDTSILIWNIDKMSCTPLKKTSIPFLNLQWSMNGSYIFTSTVGNV
FRVWNCDTWKSDRWTVANGHVQSFQWSPCGKFLLFVTSEDPVLYSLGFADEPIFNENSKK
IQQPQRALPVADLSQIEIEHSELGGVAQQLAWNGKYLGVSFKTTNSIAIFQTTIRQHQLH
ILPMFFINGMGTEFPTFITFQPSYKNSLSHRAENVLTIAWSSGRIEFYSNNLFN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g427.t1 | Gene3D | G3DSA:2.130.10.10 | - | 94 | 345 | 5.1E-26 |
| 2 | g427.t1 | PANTHER | PTHR14494 | ALADIN/ADRACALIN/AAAS | 67 | 469 | 5.4E-94 |
| 1 | g427.t1 | Pfam | PF00400 | WD domain, G-beta repeat | 234 | 264 | 1.2E-4 |
| 8 | g427.t1 | ProSitePatterns | PS00678 | Trp-Asp (WD) repeats signature. | 251 | 265 | - |
| 10 | g427.t1 | ProSiteProfiles | PS50294 | Trp-Asp (WD) repeats circular profile. | 138 | 273 | 9.678 |
| 7 | g427.t1 | SMART | SM00320 | WD40_4 | 133 | 170 | 0.58 |
| 6 | g427.t1 | SMART | SM00320 | WD40_4 | 175 | 213 | 4.0 |
| 4 | g427.t1 | SMART | SM00320 | WD40_4 | 222 | 264 | 0.0067 |
| 5 | g427.t1 | SMART | SM00320 | WD40_4 | 266 | 305 | 19.0 |
| 3 | g427.t1 | SUPERFAMILY | SSF50978 | WD40 repeat-like | 85 | 342 | 3.43E-31 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K14320 (aladin)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
