General information for g4311.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Alpha-N-acetylgalactosaminidase.
Parent gene
- The parent gene g4311 is located on chr_2: 1143563..1145278 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4311 | g4311.t3 | isoform | g4311.t3 | 1143563 | 1145278 |
| chr_2 | g4311 | g4311.t3 | exon | g4311.t3.exon1 | 1143563 | 1143737 |
| chr_2 | g4311 | g4311.t3 | cds | g4311.t3.CDS1 | 1143582 | 1143737 |
| chr_2 | g4311 | g4311.t3 | exon | g4311.t3.exon2 | 1143795 | 1143968 |
| chr_2 | g4311 | g4311.t3 | cds | g4311.t3.CDS2 | 1143795 | 1143968 |
| chr_2 | g4311 | g4311.t3 | exon | g4311.t3.exon3 | 1144026 | 1144121 |
| chr_2 | g4311 | g4311.t3 | cds | g4311.t3.CDS3 | 1144026 | 1144121 |
| chr_2 | g4311 | g4311.t3 | exon | g4311.t3.exon4 | 1144228 | 1144392 |
| chr_2 | g4311 | g4311.t3 | cds | g4311.t3.CDS4 | 1144228 | 1144392 |
| chr_2 | g4311 | g4311.t3 | exon | g4311.t3.exon5 | 1144639 | 1144801 |
| chr_2 | g4311 | g4311.t3 | cds | g4311.t3.CDS5 | 1144639 | 1144801 |
| chr_2 | g4311 | g4311.t3 | exon | g4311.t3.exon6 | 1144867 | 1145057 |
| chr_2 | g4311 | g4311.t3 | cds | g4311.t3.CDS6 | 1144867 | 1145057 |
| chr_2 | g4311 | g4311.t3 | exon | g4311.t3.exon7 | 1145117 | 1145278 |
| chr_2 | g4311 | g4311.t3 | cds | g4311.t3.CDS7 | 1145117 | 1145278 |
| chr_2 | g4311 | g4311.t3 | TTS | g4311.t3 | 1145645 | 1145645 |
| chr_2 | g4311 | g4311.t3 | TSS | g4311.t3 | NA | NA |
Sequences
>g4311.t3 Gene=g4311 Length=1126
TGAAAATCTATTTCGTACAATGGCAGATTTGGTTGTATCTGAAGGATATGCAGCAGTAGG
ATATGAATACATCAATGTGGATGATTGTTGGTTAGAAAAAAATCGTGGTCCTCGTGGTGA
ACTCGTTGCTGATAGAAAAAGATTCCCAAGTGGAATGCGTGCATTGGCAGATTATGTTCA
TGCGAAAGGTCTCAAATTTGGAATTTATGAGGATTATGGCAATTATACTTGCGCTGGCTA
CCCAGGAATTCTCGGTTCATCACGACAAGATGCTGAACAGTTTGCCTCTTGGGAAGTGGA
TTATGTCAAATTAGATGGCTGTTATTCACTTCCCACTGATATGGATGTTGGGTATCCCGA
GTTTGGAAGACATTTAAATAGAACAGGTCGACCAATGGTGTACAGCTGTAGCTGGCCTGT
GTATCAAATTTATGCTGGAATAAGTCCAAATTTCACTTCAATTATTGAGCATTGTAACTT
GTGGAGAAACTTTGATGACATTCAAGATTCATGGGCATCGCTCGAGAGTATCATTGATTA
CTATGGTAACAATCAGGACTACATCATTCCAAATGCTGGCCCAGGACATTTTAACGACGC
CGACATGCTTGGCAACTTTGGTCTTAGTTATGAACAATCAAAAACTCAAATGGCATTGTG
GGCAATTCTTGCTCAACCTTTGCTTATGTCAGTAGATTTGAGAACAATAAGACCAGAATA
TAAAGCTATTTTGCAAAATAAGAAAATTATTGCAGTCGATCAAGATCCGTTAGGAATTCA
AGGGCGAAGAATCTACAAACATAAAGGAATTGAAATTTGGTCACGACCCATCACTCCAAT
TTATCAAACTTATTACTCATATGCTGTTGCCTTCGTTAATCGTCGCACTGACGGTACACC
CAGCGATGTCGCTGTTACATTGCGTGAATTAGGTTTGCAATCACCTACAGGCTATCGTGT
TGAAGATTTGTATGAAGATGTTGATTATGGCGTTTTGTCACCAAATACTAAGATAAAGGT
CAAAGTTAATCCATCCGGTGTTGTGATTTTACGTGCTGATGTACAACCAGAGCGATTTTC
AAAGCGTCCTCTTAATCCTTTTTATTACCGTTATACGAAAAAATAA
>g4311.t3 Gene=g4311 Length=368
MADLVVSEGYAAVGYEYINVDDCWLEKNRGPRGELVADRKRFPSGMRALADYVHAKGLKF
GIYEDYGNYTCAGYPGILGSSRQDAEQFASWEVDYVKLDGCYSLPTDMDVGYPEFGRHLN
RTGRPMVYSCSWPVYQIYAGISPNFTSIIEHCNLWRNFDDIQDSWASLESIIDYYGNNQD
YIIPNAGPGHFNDADMLGNFGLSYEQSKTQMALWAILAQPLLMSVDLRTIRPEYKAILQN
KKIIAVDQDPLGIQGRRIYKHKGIEIWSRPITPIYQTYYSYAVAFVNRRTDGTPSDVAVT
LRELGLQSPTGYRVEDLYEDVDYGVLSPNTKIKVKVNPSGVVILRADVQPERFSKRPLNP
FYYRYTKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g4311.t3 | CDD | cd14792 | GH27 | 1 | 249 | 0 |
| 12 | g4311.t3 | Gene3D | G3DSA:3.20.20.70 | Aldolase class I | 1 | 251 | 0 |
| 13 | g4311.t3 | Gene3D | G3DSA:2.60.40.1180 | - | 252 | 354 | 0 |
| 3 | g4311.t3 | PANTHER | PTHR11452 | ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE | 1 | 345 | 0 |
| 4 | g4311.t3 | PANTHER | PTHR11452:SF66 | ALPHA-GALACTOSIDASE | 1 | 345 | 0 |
| 8 | g4311.t3 | PRINTS | PR00740 | Glycosyl hydrolase family 27 signature | 9 | 24 | 0 |
| 9 | g4311.t3 | PRINTS | PR00740 | Glycosyl hydrolase family 27 signature | 50 | 71 | 0 |
| 5 | g4311.t3 | PRINTS | PR00740 | Glycosyl hydrolase family 27 signature | 84 | 101 | 0 |
| 6 | g4311.t3 | PRINTS | PR00740 | Glycosyl hydrolase family 27 signature | 111 | 129 | 0 |
| 7 | g4311.t3 | PRINTS | PR00740 | Glycosyl hydrolase family 27 signature | 205 | 226 | 0 |
| 2 | g4311.t3 | Pfam | PF16499 | Alpha galactosidase A | 1 | 249 | 0 |
| 1 | g4311.t3 | Pfam | PF17450 | Alpha galactosidase A C-terminal beta sandwich domain | 252 | 340 | 0 |
| 11 | g4311.t3 | SUPERFAMILY | SSF51445 | (Trans)glycosidases | 1 | 250 | 0 |
| 10 | g4311.t3 | SUPERFAMILY | SSF51011 | Glycosyl hydrolase domain | 251 | 346 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds | MF |
| GO:0005975 | carbohydrate metabolic process | BP |
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
