General information for g432.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as NAD(P) transhydrogenase, mitochondrial.
Parent gene
- The parent gene g432 is located on chr_3: 3334450..3335449 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g432 | g432.t2 | isoform | g432.t2 | 3334450 | 3335449 |
| chr_3 | g432 | g432.t2 | exon | g432.t2.exon1 | 3334450 | 3334744 |
| chr_3 | g432 | g432.t2 | cds | g432.t2.CDS1 | 3334564 | 3334744 |
| chr_3 | g432 | g432.t2 | exon | g432.t2.exon2 | 3334803 | 3335207 |
| chr_3 | g432 | g432.t2 | cds | g432.t2.CDS2 | 3334803 | 3335207 |
| chr_3 | g432 | g432.t2 | exon | g432.t2.exon3 | 3335265 | 3335449 |
| chr_3 | g432 | g432.t2 | cds | g432.t2.CDS3 | 3335265 | 3335449 |
| chr_3 | g432 | g432.t2 | TTS | g432.t2 | 3335608 | 3335608 |
| chr_3 | g432 | g432.t2 | TSS | g432.t2 | NA | NA |
Sequences
>g432.t2 Gene=g432 Length=885
ATGGCAAAGTTTGAGATCTTACTTACTGCTGCAATCGGTGGCGCTGGTAAATTATTTTAT
TAACAATTCATCACAATTTAGAAATTTAATTGAATATTTATTTTCTTTTTAGACATGCCT
GTTGTTATTACTGTATTAAATTCATATTCTGGCTGGGCATTGTGTGCAGAAGGTTTCATG
TTGAACAACAATTTGATGACAATTGTTGGTGCTTTAATTGGAAGTTCTGGTGCAATTCTT
TCATATATTATGTGCAAAGCAATGAATCGTTCATTACCAAATGTCATTCTTGGAGGATAT
GGAACATCATCAACTGGAGGAGGCAAACCACAAGAAATTGTTGGAACGCATACGGAAGTT
TCAGTTGAAGGAACAGTCGAAATGATTAAAAATGCAAAGAACATTATCATCACACCCGGT
TATGGTCTCTGTGTTGCTAAAGCTCAATATCCAATCGCAGAAATGGTCGACATTTTGAAG
AAAGCTGGAAAGAAAGTTCGCTTTGGTATTCATCCCGTTGCAGGTCGCATGCCTGGTCAA
CTGAATGTTCTTTTGGCTGAAGCTGGTGTTAGTTACGATGATGTATTGGAAATGGAAGAA
ATTAATGATGACTTTCCTGAAACTGACTTAGTTTTGGTTATTGGTGCAAATGATACTGTC
AACTCTGCTGCTGAAGATGATCCAAATTCAATTATTGCAGGTATGCCTGTATTGAGAGTA
TGGAAGGCTGATCAAGTTGTAGTCATGAAGAGATCACTCGGTGTCGGTTATGCTGCAGTT
GACAATCCAATTTTCTACAAACCAAATACTGCTATGTTGCTAGGTGACGCAAAGAAAACT
TGTGATGCACTTTTGGGCAAAATTAAGGAAGAAATAGTAAATTAA
>g432.t2 Gene=g432 Length=256
MPVVITVLNSYSGWALCAEGFMLNNNLMTIVGALIGSSGAILSYIMCKAMNRSLPNVILG
GYGTSSTGGGKPQEIVGTHTEVSVEGTVEMIKNAKNIIITPGYGLCVAKAQYPIAEMVDI
LKKAGKKVRFGIHPVAGRMPGQLNVLLAEAGVSYDDVLEMEEINDDFPETDLVLVIGAND
TVNSAAEDDPNSIIAGMPVLRVWKADQVVVMKRSLGVGYAAVDNPIFYKPNTAMLLGDAK
KTCDALLGKIKEEIVN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g432.t2 | Gene3D | G3DSA:3.40.50.1220 | - | 73 | 255 | 2.0E-88 |
| 2 | g432.t2 | PANTHER | PTHR10160:SF30 | NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE 2 | 1 | 253 | 1.5E-153 |
| 3 | g432.t2 | PANTHER | PTHR10160 | NAD(P) TRANSHYDROGENASE | 1 | 253 | 1.5E-153 |
| 1 | g432.t2 | Pfam | PF02233 | NAD(P) transhydrogenase beta subunit | 1 | 247 | 6.3E-128 |
| 9 | g432.t2 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 17 | - |
| 10 | g432.t2 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 2 | - |
| 11 | g432.t2 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 3 | 8 | - |
| 13 | g432.t2 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 9 | 17 | - |
| 8 | g432.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 18 | 26 | - |
| 12 | g432.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 27 | 47 | - |
| 7 | g432.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 48 | 256 | - |
| 5 | g432.t2 | SUPERFAMILY | SSF52467 | DHS-like NAD/FAD-binding domain | 78 | 252 | 3.27E-75 |
| 4 | g432.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 20 | 42 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K00323 (H+-translocating NAD(P) transhydrogenase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
