General information for g4433.t17
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Ectonucleoside triphosphate diphosphohydrolase 5.
Parent gene
- The parent gene g4433 is located on chr_2: 2138905..2140409 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4433 | g4433.t17 | TSS | g4433.t17 | 2137640 | 2137640 |
| chr_2 | g4433 | g4433.t17 | isoform | g4433.t17 | 2138347 | 2139921 |
| chr_2 | g4433 | g4433.t17 | exon | g4433.t17.exon1 | 2138347 | 2138592 |
| chr_2 | g4433 | g4433.t17 | cds | g4433.t17.CDS1 | 2138454 | 2138592 |
| chr_2 | g4433 | g4433.t17 | exon | g4433.t17.exon2 | 2138662 | 2139540 |
| chr_2 | g4433 | g4433.t17 | cds | g4433.t17.CDS2 | 2138662 | 2139540 |
| chr_2 | g4433 | g4433.t17 | exon | g4433.t17.exon3 | 2139604 | 2139755 |
| chr_2 | g4433 | g4433.t17 | cds | g4433.t17.CDS3 | 2139604 | 2139755 |
| chr_2 | g4433 | g4433.t17 | exon | g4433.t17.exon4 | 2139814 | 2139921 |
| chr_2 | g4433 | g4433.t17 | cds | g4433.t17.CDS4 | 2139814 | 2139921 |
| chr_2 | g4433 | g4433.t17 | TTS | g4433.t17 | 2140138 | 2140138 |
Sequences
>g4433.t17 Gene=g4433 Length=1385
TCTCAAAAAAAGTATTATAAACATAAATTTGATAAGGAAATAAATGAATTTAGTAATTAG
CAACTCTCTCAAGCTATGATTAGTCTATCGCAAAACGTGTCATTGTAATGATGTTCATAA
TCAAACTAGTTTTTTTAATATCTTTTATTTTTAGTGTTTATACTGATTCACTACATCCCA
TTGTCGATCAGATTGCTACACAGCTTGGCTATTCAGAAAAGCAATATGGTGCAATTATTG
ATGCTGGCTCAACTGGCAGTCGTGTGTTAGCTTTTGAATTTCATAAAGCATATCTTGATG
GACGACTTGTATTAGATAACGAATTATTTAGAGAATTGAAGCCCGGACTATCCTCTTTGA
CACCGGACAAAGGTGCAGAACAAATTACAAGATTACTAAAGGAGGCTAAAGATTTTATTC
CTGCCGAATATAGAAGAAAAACTCCTATCGCTTTAAAAGCTACTGCCGGCTTAAGATTAT
TAGGTGCAGCAAAATCTGAAGCAATTCTAGAAAAAATTCGTGAAGTTTTTGCACAATCTG
GATTTTTAATCAACGATGATTCAGTAGAGATTATGGATGGAACTGATGAAGGCATATTCT
CATGGTTCACAGTCAATTATCTCTCAAATCGACTGACATCACGTAACACTGCAGCTGCAT
TAGATTTAGGTGGAGGTTCTACACAAGTGACTTACGAATTAAACGAGAATTTGCCAAGCT
ATAAAGAATATATTCACACTGTGCCTGTACTCAATTCTGAATTGAATGTTTTTACTAACT
CCTATCTTGGTTTAGGTTTGATGGCGTTACGTCATGCTGTAATTACTTATCAAAAGGCTG
ATAATCAAACATCATTTGCAAGTGAATGTATTAATCCCATTATAAAGGATAAAGTTTGGA
CCTATCAAAATATCGACTACCTTGTATCTGGAAAAGAAAATAAAAATCAAGCCTCAAATC
CAGAAAACCCCGAAGTAAATTTTGACCTTTGTGTAGAGTCAGTAAAGCGACAAGTAATGC
CATTATTAAAACCAAAACCAATTAAATTGCAAGAGCACGTGATTAATGCGTTTTCCTATT
ATTATGATCGTGCCATTGAAGTTGGTTTGGTTGATCCATATTTAGGAGGTGAAAATACTG
TTGCAGATTTCTCTAAAAAGGCTCGTGAAGTCTGTGCAACAGCTAATGCTGATCAACCAT
TTATGTGCTTAGATTTGGTTTACATATCAGTATTACTTCAAGATGGATTCGGTCTCAAAC
CACAAACAAATATAAAGCTTTACAAAAAAATAAGAGGACATGAAGTTTCGTGGGCTTTGG
GCTGTTTCTTTCAAAATTATAATATCCTACAGCAAAAAATGAAACGAGTAGCTGGTGTGA
ATTAG
>g4433.t17 Gene=g4433 Length=425
MMFIIKLVFLISFIFSVYTDSLHPIVDQIATQLGYSEKQYGAIIDAGSTGSRVLAFEFHK
AYLDGRLVLDNELFRELKPGLSSLTPDKGAEQITRLLKEAKDFIPAEYRRKTPIALKATA
GLRLLGAAKSEAILEKIREVFAQSGFLINDDSVEIMDGTDEGIFSWFTVNYLSNRLTSRN
TAAALDLGGGSTQVTYELNENLPSYKEYIHTVPVLNSELNVFTNSYLGLGLMALRHAVIT
YQKADNQTSFASECINPIIKDKVWTYQNIDYLVSGKENKNQASNPENPEVNFDLCVESVK
RQVMPLLKPKPIKLQEHVINAFSYYYDRAIEVGLVDPYLGGENTVADFSKKAREVCATAN
ADQPFMCLDLVYISVLLQDGFGLKPQTNIKLYKKIRGHEVSWALGCFFQNYNILQQKMKR
VAGVN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g4433.t17 | CDD | cd00012 | NBD_sugar-kinase_HSP70_actin | 42 | 199 | 3.62475E-6 |
| 6 | g4433.t17 | Gene3D | G3DSA:3.30.420.40 | - | 39 | 406 | 2.8E-73 |
| 5 | g4433.t17 | Gene3D | G3DSA:3.30.420.150 | Exopolyphosphatase. Domain 2 | 157 | 396 | 2.8E-73 |
| 2 | g4433.t17 | PANTHER | PTHR11782:SF35 | ECTONUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 5 | 20 | 414 | 4.5E-96 |
| 3 | g4433.t17 | PANTHER | PTHR11782 | ADENOSINE/GUANOSINE DIPHOSPHATASE | 20 | 414 | 4.5E-96 |
| 1 | g4433.t17 | Pfam | PF01150 | GDA1/CD39 (nucleoside phosphatase) family | 36 | 416 | 1.2E-64 |
| 8 | g4433.t17 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 19 | - |
| 9 | g4433.t17 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 6 | - |
| 10 | g4433.t17 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 7 | 15 | - |
| 11 | g4433.t17 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 16 | 19 | - |
| 7 | g4433.t17 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 20 | 425 | - |
| 4 | g4433.t17 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016787 | hydrolase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01511 (ectonucleoside triphosphate diphosphohydrolase 5/6)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
