General information for g4451.t6
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative oxidoreductase GLYR1-like protein.
Parent gene
- The parent gene g4451 is located on chr_2: 2444865..2445921 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4451 | g4451.t6 | TSS | g4451.t6 | 2442641 | 2442641 |
| chr_2 | g4451 | g4451.t6 | isoform | g4451.t6 | 2443498 | 2445921 |
| chr_2 | g4451 | g4451.t6 | exon | g4451.t6.exon1 | 2443498 | 2443695 |
| chr_2 | g4451 | g4451.t6 | exon | g4451.t6.exon2 | 2443757 | 2444660 |
| chr_2 | g4451 | g4451.t6 | cds | g4451.t6.CDS1 | 2443775 | 2444660 |
| chr_2 | g4451 | g4451.t6 | exon | g4451.t6.exon3 | 2444717 | 2444806 |
| chr_2 | g4451 | g4451.t6 | cds | g4451.t6.CDS2 | 2444717 | 2444806 |
| chr_2 | g4451 | g4451.t6 | exon | g4451.t6.exon4 | 2444866 | 2445921 |
| chr_2 | g4451 | g4451.t6 | cds | g4451.t6.CDS3 | 2444866 | 2445068 |
| chr_2 | g4451 | g4451.t6 | TTS | g4451.t6 | 2445918 | 2445918 |
Sequences
>g4451.t6 Gene=g4451 Length=2248
GCATCTGAAACAATAATAACACCGGCAAGGAAAAAATCGCTACCCAAAGTAAGACAATCA
ATAACGTCAGCAGATGAGAGCATTGTTAAAGAGGAAATTGCAGAAGATATAAACGATGTT
GCAAGTGGAGTTGAAGAAGATGAGATTGAAACGCCAAAGAAAGTTGTTGCAAAAGTTCCA
GTCAAGAAGAATTCGACACAGAAAAAGTCAAAAGTAATGAGTGCAAAGAAAAAAGCTGAA
GTTGATAGCGGTGACATAGAAATTCCACCACCAAAAAGAGCACGTGTATCAAGTTCAAAT
TTGCTTGCTCGTAATCATTCTATCAATAATAACAATAATGATTCAATCAGCTCATCAGAA
ATGGTTTCACAAAAAGAATATTCCTCACCAGTGCCTCGTTCACGTGTTGCTCGTGCAGTC
ATTGATCGTCCAGAGATCATTTATACTAAACCAGAGTACTCTGAATTGGATGTAAAAACT
ATTACAGATACATTGAAATCAAAGAAAATAACTGCATCTACGAGTAAATTTGGTTTCATT
GGTCTCGGCATTATGGGTAGTGGCATAGTCAAAAATCTTATCAACTCTGGACATGAAGTA
TATGTTTATAATCGAACTAAAGACAAAACACTAAAGTTTGAGGAAGCTGGTGCTACTGTT
TTGATTACACCAAGTGATGTAGTCGAAAATTCTGATATAACGTTCTCGTGTGTATCCGAT
CCACAAGCACTGAGAGATACAATTTTTGGAACTTATGGCGTTAGCTCATTACAACCTGAA
TTAGCTCAAGGAAAAGGATATGTTGAAATGACAACAATTGATGCTGACACATCGAGAGAT
ATTGAAAGTGCATTGACATCGATAGGCATGCAATATTTGGAAGCACAAATTCATGGTACA
AAAGAGCAAGCTGAAGAGGGAAAGCTTATTATTTTAGCAGCAGGTAGCAAACAAATTTTC
GACTCCTGTCAAACATGCTTTGAAGCTATGGGTAGAAATTCATTTTTTGTTGGTGAAACG
GGAAATGCAACAAAAATGAATTTAGTTTTACAAGCTATTTCGGGTGTAACTATTGCTGGA
CTTGCAGATTCTCTAGCACTTGCAAAAAGATCAGGATTAAAAACGGAAAAAGTGATGGAA
ATTCTTTCAAATACAAATTTAAAATCAGATTTGATAATGGACAAAGGATATGCAATGGTT
GAAGGTCGATATCATCACGTCAATCTACCACTACAGCACTTGCAAAAAGATCTCCGTTTA
GCCACAAATATGGCAGATAGCCTCAATCATCCTTTATCATTAACAGCTATTGCAAATGAA
GCATACAAGAATTGTCGTCGCGTTGGATTAGGTGAAAGCGATGCAAGCGCTATACATTAT
CGTGCTCTTAACTAACAAAAAAAGTTTGCAAACAATGAGTTTCTAAAATATTTTAACAAA
AAATGATCCAACAACGGACCAACTTCCGATAATGATGAATGAAAAACAATTGATGAGTAA
TAGAAAAAAAGCTACTCAAGAAATTTCAAAATATTTACATTAATTTTCATAGATAAATTT
TACTTTTGAGTAAAAGTTTAAAAATTAAACTTTAAATTTCGTTCATAATTTTTCATGAAG
GGATTTTTTTTCTTTAATTATTTCTTTTATCTTTAAATATCCTTTTTTTATTAGTCAATT
ACATAAATTTTAGACAATTCTTTATCATTATGAAAAGAATCTACATATATTTTATAATTT
TTCTGATATATTGATTTTTTTTTTGTTTATTAAGACTCAAAAAGTTAGGTTTGTCGAGTA
TTTAATTGTGGAAAAATTACAACACAAACAAAACATGTAACCAGACAAAATTGATTGCTA
ATTAAAATGAAAGATATGTATCTAAATTACTTGCATGTCAACTAAAAACACAGTATGACC
ACTTAAAATTAATAGTTAATGAAAATGTAAGAGTTGCAAGTCACTACTTTATATCATCTT
CATAAGAGACCGATACAAATACATAAATGCATACAAATTCATTTATTTTTTAAAAGAAAC
AACATTTTTAAAATGATAAAAAAAAGTTATAGATGATGACATTTTAATGAATTAAATTGA
ATGAAATTAATGAAAAATTATTTTCTGATAATAATGAGCTAGGCAAAGTCTATGTGGATG
ATAATGAAGATTTACAATTAGTAGTTGATACATAAAATAAAATGTAATAAACATAAGAAA
AATTTGCAATAAAATCCGTTTAAAGAAA
>g4451.t6 Gene=g4451 Length=392
MSAKKKAEVDSGDIEIPPPKRARVSSSNLLARNHSINNNNNDSISSSEMVSQKEYSSPVP
RSRVARAVIDRPEIIYTKPEYSELDVKTITDTLKSKKITASTSKFGFIGLGIMGSGIVKN
LINSGHEVYVYNRTKDKTLKFEEAGATVLITPSDVVENSDITFSCVSDPQALRDTIFGTY
GVSSLQPELAQGKGYVEMTTIDADTSRDIESALTSIGMQYLEAQIHGTKEQAEEGKLIIL
AAGSKQIFDSCQTCFEAMGRNSFFVGETGNATKMNLVLQAISGVTIAGLADSLALAKRSG
LKTEKVMEILSNTNLKSDLIMDKGYAMVEGRYHHVNLPLQHLQKDLRLATNMADSLNHPL
SLTAIANEAYKNCRRVGLGESDASAIHYRALN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g4451.t6 | Gene3D | G3DSA:3.40.50.720 | - | 87 | 266 | 1.0E-45 |
| 11 | g4451.t6 | Gene3D | G3DSA:1.10.1040.10 | - | 269 | 389 | 8.1E-24 |
| 8 | g4451.t6 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 57 | - |
| 9 | g4451.t6 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 17 | - |
| 7 | g4451.t6 | MobiDBLite | mobidb-lite | consensus disorder prediction | 26 | 57 | - |
| 3 | g4451.t6 | PANTHER | PTHR43580 | OXIDOREDUCTASE GLYR1-RELATED | 98 | 390 | 1.1E-101 |
| 4 | g4451.t6 | PANTHER | PTHR43580:SF2 | OXIDOREDUCTASE GLYR1-RELATED | 98 | 390 | 1.1E-101 |
| 2 | g4451.t6 | Pfam | PF03446 | NAD binding domain of 6-phosphogluconate dehydrogenase | 104 | 266 | 1.3E-36 |
| 1 | g4451.t6 | Pfam | PF14833 | NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase | 269 | 386 | 4.4E-19 |
| 5 | g4451.t6 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 104 | 267 | 1.31E-37 |
| 6 | g4451.t6 | SUPERFAMILY | SSF48179 | 6-phosphogluconate dehydrogenase C-terminal domain-like | 267 | 387 | 4.19E-22 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0050661 | NADP binding | MF |
| GO:0051287 | NAD binding | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
