General information for g4451.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative oxidoreductase GLYR1-like protein.
Parent gene
- The parent gene g4451 is located on chr_2: 2444865..2445921 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4451 | g4451.t8 | isoform | g4451.t8 | 2444132 | 2445559 |
| chr_2 | g4451 | g4451.t8 | exon | g4451.t8.exon1 | 2444132 | 2444660 |
| chr_2 | g4451 | g4451.t8 | cds | g4451.t8.CDS1 | 2444366 | 2444660 |
| chr_2 | g4451 | g4451.t8 | exon | g4451.t8.exon2 | 2444717 | 2444806 |
| chr_2 | g4451 | g4451.t8 | cds | g4451.t8.CDS2 | 2444717 | 2444806 |
| chr_2 | g4451 | g4451.t8 | exon | g4451.t8.exon3 | 2444866 | 2445559 |
| chr_2 | g4451 | g4451.t8 | cds | g4451.t8.CDS3 | 2444866 | 2445068 |
| chr_2 | g4451 | g4451.t8 | TTS | g4451.t8 | 2445918 | 2445918 |
| chr_2 | g4451 | g4451.t8 | TSS | g4451.t8 | NA | NA |
Sequences
>g4451.t8 Gene=g4451 Length=1313
AATCTTATCAACTCTGGACATGAAGTATATGTTTATAATCGAACTAAAGACAAAACACTA
AAGTTTGAGGAAGCTGGTGCTACTGTTTTGATTACACCAAGTGATGTAGTCGAAAATTCT
GATATAACGTTCTCGTGTGTATCCGATCCACAAGCACTGAGAGATACAATTTTTGGAACT
TATGGCGTTAGCTCATTACAACCTGAATTAGCTCAAGGAAAAGGATATGTTGAAATGACA
ACAATTGATGCTGACACATCGAGAGATATTGAAAGTGCATTGACATCGATAGGCATGCAA
TATTTGGAAGCACAAATTCATGGTACAAAAGAGCAAGCTGAAGAGGGAAAGCTTATTATT
TTAGCAGCAGGTAGCAAACAAATTTTCGACTCCTGTCAAACATGCTTTGAAGCTATGGGT
AGAAATTCATTTTTTGTTGGTGAAACGGGAAATGCAACAAAAATGAATTTAGTTTTACAA
GCTATTTCGGGTGTAACTATTGCTGGACTTGCAGATTCTCTAGCACTTGCAAAAAGATCA
GGATTAAAAACGGAAAAAGTGATGGAAATTCTTTCAAATACAAATTTAAAATCAGATTTG
ATAATGGACAAAGGATATGCAATGGTTGAAGGTCGATATCATCACGTCAATCTACCACTA
CAGCACTTGCAAAAAGATCTCCGTTTAGCCACAAATATGGCAGATAGCCTCAATCATCCT
TTATCATTAACAGCTATTGCAAATGAAGCATACAAGAATTGTCGTCGCGTTGGATTAGGT
GAAAGCGATGCAAGCGCTATACATTATCGTGCTCTTAACTAACAAAAAAAGTTTGCAAAC
AATGAGTTTCTAAAATATTTTAACAAAAAATGATCCAACAACGGACCAACTTCCGATAAT
GATGAATGAAAAACAATTGATGAGTAATAGAAAAAAAGCTACTCAAGAAATTTCAAAATA
TTTACATTAATTTTCATAGATAAATTTTACTTTTGAGTAAAAGTTTAAAAATTAAACTTT
AAATTTCGTTCATAATTTTTCATGAAGGGATTTTTTTTCTTTAATTATTTCTTTTATCTT
TAAATATCCTTTTTTTATTAGTCAATTACATAAATTTTAGACAATTCTTTATCATTATGA
AAAGAATCTACATATATTTTATAATTTTTCTGATATATTGATTTTTTTTTTGTTTATTAA
GACTCAAAAAGTTAGGTTTGTCGAGTATTTAATTGTGGAAAAATTACAACACAAACAAAA
CATGTAACCAGACAAAATTGATTGCTAATTAAAATGAAAGATATGTATCTAAA
>g4451.t8 Gene=g4451 Length=195
MTTIDADTSRDIESALTSIGMQYLEAQIHGTKEQAEEGKLIILAAGSKQIFDSCQTCFEA
MGRNSFFVGETGNATKMNLVLQAISGVTIAGLADSLALAKRSGLKTEKVMEILSNTNLKS
DLIMDKGYAMVEGRYHHVNLPLQHLQKDLRLATNMADSLNHPLSLTAIANEAYKNCRRVG
LGESDASAIHYRALN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g4451.t8 | Coils | Coil | Coil | 191 | 195 | - |
| 7 | g4451.t8 | Gene3D | G3DSA:3.40.50.12340 | - | 1 | 70 | 3.5E-15 |
| 8 | g4451.t8 | Gene3D | G3DSA:1.10.1040.10 | - | 72 | 192 | 1.5E-24 |
| 3 | g4451.t8 | PANTHER | PTHR43580 | OXIDOREDUCTASE GLYR1-RELATED | 1 | 193 | 1.4E-63 |
| 4 | g4451.t8 | PANTHER | PTHR43580:SF2 | OXIDOREDUCTASE GLYR1-RELATED | 1 | 193 | 1.4E-63 |
| 2 | g4451.t8 | Pfam | PF03446 | NAD binding domain of 6-phosphogluconate dehydrogenase | 1 | 69 | 3.7E-10 |
| 1 | g4451.t8 | Pfam | PF14833 | NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase | 72 | 189 | 8.3E-20 |
| 5 | g4451.t8 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 1 | 70 | 4.61E-10 |
| 6 | g4451.t8 | SUPERFAMILY | SSF48179 | 6-phosphogluconate dehydrogenase C-terminal domain-like | 70 | 190 | 7.71E-23 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0050661 | NADP binding | MF |
| GO:0051287 | NAD binding | MF |
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
