General information for g446.t6
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 26S proteasome non-ATPase regulatory subunit 11.
Parent gene
- The parent gene g446 is located on chr_3: 3377665..3378538 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g446 | g446.t6 | TSS | g446.t6 | 3376534 | 3376534 |
| chr_3 | g446 | g446.t6 | isoform | g446.t6 | 3376641 | 3378538 |
| chr_3 | g446 | g446.t6 | exon | g446.t6.exon1 | 3376641 | 3377172 |
| chr_3 | g446 | g446.t6 | exon | g446.t6.exon2 | 3377336 | 3377605 |
| chr_3 | g446 | g446.t6 | cds | g446.t6.CDS1 | 3377558 | 3377605 |
| chr_3 | g446 | g446.t6 | exon | g446.t6.exon3 | 3377663 | 3378538 |
| chr_3 | g446 | g446.t6 | cds | g446.t6.CDS2 | 3377663 | 3378106 |
| chr_3 | g446 | g446.t6 | TTS | g446.t6 | 3378528 | 3378528 |
Sequences
>g446.t6 Gene=g446 Length=1678
ATGGCAGGAGCTACAAGTTTTGAGAGAACTCAGTCTATCACTTCAATTGGACGCGCAGAG
GAGAGTGAAAAGCTTTTAAATAAAATTCTCAAGGATCTCGAAATGAACGAGAATGATGAA
GAGCAAATTCGCATTAAAGAGGCCGCAATCTTAGAATTGGGCCAGTTTTACAAGACACAA
GGAAAGGCTAAGGAGCTTGCAGATCTAATTTCTAAATCCCGTCCGTTCCTTAATCTCATT
TCTAAAGCAAAGGCAGCAAAGTTAGTGCGTAGCCTTGTCGATCTATTTTTGGATCTTGAA
GCTGGAACTGGCATAGAAGTTCAATTGTGCAAAGACTGCATAGAATGGGCAAAACAAGAA
AAGAGAACTTTCTTACGTCAATCTTTAGAAGCAAGATTGATTGCTTTGTATTTCGACACA
AAGATGTACTCTGAAGCACTAACTCTCGGATCACAGCTCCTTCGTGAGTTAAAGAAAATG
GATGATAAGAACTTGCTAGTTGAAGTGCAGTTATTAGAAAGTAAAACCTATCGCTCGTGC
TGCACTTACATCTGCAAGAACAACAGCAAATTCAATTTATTGTCCTCCAAAAGTTCAAGC
TGCTCTCGATTTGCAATCTGGTATTCTTCATGCTGCAGATGAACGTGATTTTAAGACAGC
CTTTTCTTATTTCTATGAAGCGTTTGAAGGATATGACAGTGTTGAAAATGTTAAAGCATT
AACTGCACTCAAATACATGTTATTGTGCAAAATTATGCTTGGTCAAAGTGATGATGTTAA
TCAAATTGTTAGTGGAAAATTGGCAATTTCATATTCTGGAAAAGACATTGACGCAATGAA
AGCTGTTGCTCAAGCATCACACAAGCGTTCACTTGCAGACTTTCAACAAGCACTAAAGGA
ATTCAAATCACAACTCGAAGACGATGTAATAGTTCGTGCACATTTAGATTCATTATATGA
TACAATGTTAGAGCAAAATCTTTGTCGCATCATTGAACCTTATTCTCGTGTTCAAGTGTC
GTTTATTGCAAATTCTATCAAATTACCAATTCAGCAAGTTGAAAAAAAATTGTCTCAAAT
GATTTTGGATAAAAAGTTTAGTGGTATCCTTGATCAAGGAGATGGTGTATTAATTGTGTT
TGAAGAAACACCAATTGATAAGACTTATGAAACTGCACTAGAGACAATTCATCATATGGG
GAAAGTTGTAGATACATTGTATCAAAAGGCTAAGAAATTATCATAAATATATTGACATTC
GATTCGATGCACATGCACTTCATCCTACTTTTCTAGTTCTCATATCTCTTTTTAATTTTA
TTTGTAAATCCTCTTGCGCCTGTAATTTTTCTTAAAAAGATGAGATTTACAAAAAATCTT
AATTATTAAAAAATATTCGATATATAACAATTTTATTCCTTACTAATATTTTTCTTTTGG
CATGTAGAGTTAATGCTTTTTATGTGAGAACGAATAAATTGGATGATAATGAAGAATGTG
AATGAGGAGGGAGAAGTGTGAAAATAAAAAATTTCTTAGAACTTAAGATTATTATAATCT
AGCTGTTGAGAGTAAAATTTATTCGAAAATTGATATTTTGTATAAATCGTATGAATAACG
AATTGAATAAGGAATTCTTAATAAAAATTATCACGAGTATGGAGACACAAATTTTTTT
>g446.t6 Gene=g446 Length=163
MLGQSDDVNQIVSGKLAISYSGKDIDAMKAVAQASHKRSLADFQQALKEFKSQLEDDVIV
RAHLDSLYDTMLEQNLCRIIEPYSRVQVSFIANSIKLPIQQVEKKLSQMILDKKFSGILD
QGDGVLIVFEETPIDKTYETALETIHHMGKVVDTLYQKAKKLS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g446.t6 | Gene3D | G3DSA:1.25.40.570 | - | 1 | 163 | 0.000 |
| 3 | g446.t6 | PANTHER | PTHR10678 | 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 | 1 | 161 | 0.000 |
| 4 | g446.t6 | PANTHER | PTHR10678:SF2 | 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11 | 1 | 161 | 0.000 |
| 2 | g446.t6 | Pfam | PF01399 | PCI domain | 27 | 128 | 0.000 |
| 1 | g446.t6 | Pfam | PF18503 | 26S proteasome subunit RPN6 C-terminal helix domain | 135 | 160 | 0.000 |
| 9 | g446.t6 | ProSiteProfiles | PS50250 | PCI domain profile. | 1 | 133 | 19.933 |
| 6 | g446.t6 | SMART | SM00088 | PINT_4 | 62 | 145 | 0.000 |
| 7 | g446.t6 | SMART | SM00753 | motif in proteasome subunits, Int-6, Nip-1 and TRIP-15 | 62 | 145 | 0.000 |
| 5 | g446.t6 | SUPERFAMILY | SSF46785 | Winged helix DNA-binding domain | 56 | 138 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
