General information for g4497.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Prolyl endopeptidase.
Parent gene
- The parent gene g4497 is located on chr_2: 2911052..2912184 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4497 | g4497.t4 | isoform | g4497.t4 | 2911052 | 2912184 |
| chr_2 | g4497 | g4497.t4 | exon | g4497.t4.exon1 | 2911052 | 2911752 |
| chr_2 | g4497 | g4497.t4 | cds | g4497.t4.CDS1 | 2911053 | 2911752 |
| chr_2 | g4497 | g4497.t4 | exon | g4497.t4.exon2 | 2911814 | 2912184 |
| chr_2 | g4497 | g4497.t4 | cds | g4497.t4.CDS2 | 2911814 | 2912088 |
| chr_2 | g4497 | g4497.t4 | TSS | g4497.t4 | 2912310 | 2912310 |
| chr_2 | g4497 | g4497.t4 | TTS | g4497.t4 | NA | NA |
Sequences
>g4497.t4 Gene=g4497 Length=1072
ATGGCACCATCAATTCAATATCCGCAAGTGAGAAAAGAAGAAATTACTGAAACCTTTTTT
GGCCATAAAGTAAGTTTCAATTGATTATCTGATTTGATGAGCACACAACAATTAAAGCTT
TATCTTTTTCCTAGAAAATTACTTTATTTACAAATGCTGAATATTTATAATTGTGTTGTT
TTACAGATTTCTGATCCATATAGATATTTAGAAAATCCAGATAGTGAAGAAACGAAACAA
TTCATAGACAATCAAAATTTGATTTCTAAACCCTTTCTTGAGGAAAATGAATTTTGGGGA
AAAATCAATAAAAAACTTACAGACCTATGGAACTTTGAAAAGTATAATGTTGCATATAAG
CGAGGAAAGAGATATTTTTACTCGTACAATACTGGTCTACAAAATCAAAATGTAATTTAT
TATCAAGAATCGCTTGATGGTGAGAGAAAAGTCTTTCTCGATCCAAATGAACTCTCATCA
GATGGAACGGTTGCTCTGCAAAGTCTGCATTTTACAAAGGATGGATCTTTGTTAGCATAT
GGATTGTCAGAAAGTGGTAGTGATTGGGTAAAAATCAAGTTTAGGGATGTTGAGAAGAAT
GAAGATTTCCCTGAAACACTTGAGCATAGCAAATTCTTTACACCTACTTGGACGCATGAT
AATAAAGGTGTATTTTATGGAAAATTTCTACCTCAAGGAACTGCTGATGGTTGCGAAACT
AATGCAAATGAGAATCAAAAAGTGTACTATCATAGAATAGGCACATCACAAGATTCTGAT
GTTCTCGTGGCTGAATTTCCTGAGGAACCGAATTGGCGTTTTTCAGCAGAAGTATCTGAT
TGTGGTCATTATTTATTATTTTATGTTATGTATGGTTGCAATGATCACCTTATTTATTTT
GCTGATTTGCGAAAAACACCTGAAATAACAGGAAAATTGGAATTTACAAAAGTTGTAACA
GAATTCAAGAATGATTATGATTACATCACAAATAATGAAAGTATTTTCTATTTCCGTACT
AATAAAGGAGCACCAAATTATCATATAATTGCAATAGATTTTGAAAACTATG
>g4497.t4 Gene=g4497 Length=325
MSTQQLKLYLFPRKLLYLQMLNIYNCVVLQISDPYRYLENPDSEETKQFIDNQNLISKPF
LEENEFWGKINKKLTDLWNFEKYNVAYKRGKRYFYSYNTGLQNQNVIYYQESLDGERKVF
LDPNELSSDGTVALQSLHFTKDGSLLAYGLSESGSDWVKIKFRDVEKNEDFPETLEHSKF
FTPTWTHDNKGVFYGKFLPQGTADGCETNANENQKVYYHRIGTSQDSDVLVAEFPEEPNW
RFSAEVSDCGHYLLFYVMYGCNDHLIYFADLRKTPEITGKLEFTKVVTEFKNDYDYITNN
ESIFYFRTNKGAPNYHIIAIDFENY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g4497.t4 | Gene3D | G3DSA:2.130.10.120 | Prolyl oligopeptidase | 81 | 325 | 0 |
| 2 | g4497.t4 | PANTHER | PTHR42881:SF2 | PROLYL ENDOPEPTIDASE | 28 | 324 | 0 |
| 3 | g4497.t4 | PANTHER | PTHR42881 | PROLYL ENDOPEPTIDASE | 28 | 324 | 0 |
| 1 | g4497.t4 | Pfam | PF02897 | Prolyl oligopeptidase, N-terminal beta-propeller domain | 30 | 324 | 0 |
| 4 | g4497.t4 | SUPERFAMILY | SSF50993 | Peptidase/esterase ‘gauge’ domain | 30 | 324 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
