General information for g4611.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cytochrome P450 4g15.
Parent gene
- The parent gene g4611 is located on chr_2: 3553893..3559094 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4611 | g4611.t3 | isoform | g4611.t3 | 3553893 | 3557852 |
| chr_2 | g4611 | g4611.t3 | exon | g4611.t3.exon1 | 3553893 | 3554090 |
| chr_2 | g4611 | g4611.t3 | exon | g4611.t3.exon2 | 3554640 | 3554822 |
| chr_2 | g4611 | g4611.t3 | cds | g4611.t3.CDS1 | 3554750 | 3554822 |
| chr_2 | g4611 | g4611.t3 | exon | g4611.t3.exon3 | 3557332 | 3557852 |
| chr_2 | g4611 | g4611.t3 | cds | g4611.t3.CDS2 | 3557332 | 3557852 |
| chr_2 | g4611 | g4611.t3 | TSS | g4611.t3 | NA | NA |
| chr_2 | g4611 | g4611.t3 | TTS | g4611.t3 | NA | NA |
Sequences
>g4611.t3 Gene=g4611 Length=902
TTGTCTTTAAAACAGTCACAGAAAAAGGAAAAGAATTTAATCAAGTAATCAAACTATGGG
CTGGTCCAAAACTTCTTGTTTTCTTGGTTGATCCTCGTGATATTGAACTTGTATTGAGCA
GTCAAGTTTATCTTGAAAAATCACCAGAGTATAGATTTTTTGAACCATGGTTAGGTCAAG
GATTGTTAATTAGTTCAGGTCAAAAATGGCGAGCCCATCGTAAATTAATTGCACCAACTT
TTCATCTAAATGTTTTGAAAAGTTTCATTGAACTCTTTAATGATAACTCGCGACTTGTAT
GCAAAAAAATGCTAGCATTGAATGGTAAAACTTTTGATTGTCATGATTATATGTCAGAAT
GTACAGTCGAAATTCTTTTGGAAACGGCAATGGGTGTCTCGCGCAAGACTCAAGATCAAT
CTGGTTTCGATTATGCAATGGCTGTTATGAAAATGTGCGATATTCTGCATCTTCGTCATA
CAAAGCTTTGGCTTTATCCTGATTTTCTTTTTAAACTCTCAAAATACTCGAAACTTCAAG
TCAACCTTTTGGATAAAATTCACAGTCTTACAAAGAAAGTGATTAAAAGTAAAAAAGAAG
CTTTTTCAAAAGGAACACGTGGAACTTTGGCAACACCAGAATTCATTAAGCCTGAAGAGA
AACAAGAGAAGTCAAAGGAAGAAAAGAAAGCAGAAACAACAGTTGTAGAAGGACTTTCAT
TTGGACAATCTGCTGGATTAAAAGATGATTTAGATGTTGATGATGGTATGGATGTTGGTG
AAAAGAAACGATTGGCTTTCTTAGATTTATTATTGGAAAGTGCTGAAAATGGTGCAGTTA
TATCTGAACAAGAAATTAAAGAACAAGTGGATACAATCATGTTTGAGGGCCATGACACGA
CG
>g4611.t3 Gene=g4611 Length=198
MLALNGKTFDCHDYMSECTVEILLETAMGVSRKTQDQSGFDYAMAVMKMCDILHLRHTKL
WLYPDFLFKLSKYSKLQVNLLDKIHSLTKKVIKSKKEAFSKGTRGTLATPEFIKPEEKQE
KSKEEKKAETTVVEGLSFGQSAGLKDDLDVDDGMDVGEKKRLAFLDLLLESAENGAVISE
QEIKEQVDTIMFEGHDTT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g4611.t3 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 1 | 139 | 7.7E-9 |
| 8 | g4611.t3 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 144 | 198 | 3.9E-6 |
| 6 | g4611.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 110 | 129 | - |
| 7 | g4611.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 111 | 129 | - |
| 3 | g4611.t3 | PANTHER | PTHR24291:SF106 | CYTOCHROME P450 4G1-RELATED | 5 | 198 | 1.4E-73 |
| 4 | g4611.t3 | PANTHER | PTHR24291 | CYTOCHROME P450 FAMILY 4 | 5 | 198 | 1.4E-73 |
| 1 | g4611.t3 | Pfam | PF00067 | Cytochrome P450 | 7 | 131 | 2.1E-8 |
| 2 | g4611.t3 | Pfam | PF00067 | Cytochrome P450 | 157 | 198 | 5.1E-6 |
| 5 | g4611.t3 | SUPERFAMILY | SSF48264 | Cytochrome P450 | 4 | 198 | 2.49E-16 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0020037 | heme binding | MF |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | MF |
| GO:0005506 | iron ion binding | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed