General information for g4690.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ABC transporter G family member 23.
Parent gene
- The parent gene g4690 is located on chr_2: 4219107..4223647 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4690 | g4690.t1 | isoform | g4690.t1 | 4219107 | 4223647 |
| chr_2 | g4690 | g4690.t1 | exon | g4690.t1.exon1 | 4219107 | 4219210 |
| chr_2 | g4690 | g4690.t1 | cds | g4690.t1.CDS1 | 4219107 | 4219210 |
| chr_2 | g4690 | g4690.t1 | exon | g4690.t1.exon2 | 4219371 | 4219393 |
| chr_2 | g4690 | g4690.t1 | cds | g4690.t1.CDS2 | 4219371 | 4219393 |
| chr_2 | g4690 | g4690.t1 | exon | g4690.t1.exon3 | 4219526 | 4220417 |
| chr_2 | g4690 | g4690.t1 | cds | g4690.t1.CDS3 | 4219526 | 4220417 |
| chr_2 | g4690 | g4690.t1 | exon | g4690.t1.exon4 | 4220655 | 4221240 |
| chr_2 | g4690 | g4690.t1 | cds | g4690.t1.CDS4 | 4220655 | 4221240 |
| chr_2 | g4690 | g4690.t1 | exon | g4690.t1.exon5 | 4221352 | 4221699 |
| chr_2 | g4690 | g4690.t1 | cds | g4690.t1.CDS5 | 4221352 | 4221699 |
| chr_2 | g4690 | g4690.t1 | exon | g4690.t1.exon6 | 4221775 | 4221787 |
| chr_2 | g4690 | g4690.t1 | cds | g4690.t1.CDS6 | 4221775 | 4221787 |
| chr_2 | g4690 | g4690.t1 | exon | g4690.t1.exon7 | 4223351 | 4223360 |
| chr_2 | g4690 | g4690.t1 | cds | g4690.t1.CDS7 | 4223351 | 4223360 |
| chr_2 | g4690 | g4690.t1 | exon | g4690.t1.exon8 | 4223431 | 4223647 |
| chr_2 | g4690 | g4690.t1 | cds | g4690.t1.CDS8 | 4223431 | 4223647 |
| chr_2 | g4690 | g4690.t1 | TTS | g4690.t1 | 4223777 | 4223777 |
| chr_2 | g4690 | g4690.t1 | TSS | g4690.t1 | NA | NA |
Sequences
>g4690.t1 Gene=g4690 Length=2193
ATGCATGCAGTTGAGGTTCGAAATGCTTACAAATATTATGGGAAGGCGAAAGATCCAAAG
ATTGTCTTAAACAAACTAAATATGACAGTCTCGCCTGGCTCAATTTACGGACTCATGGGA
GCAAGCGGATGTGGGAAGACAACACTTTTATCGTGTATCATTGGCATGATTGGTCTTGAT
GGTGGTGAAATCACAGCACTTGGTCATAAGACGAAAGCGAATGAAATACAAAAGGCGGGT
CATCGTATTGGCTATATGCCACAAGAGACAGCATTAATTGGTGAATTAACGATCAAAGAA
ACAATTTATTATTTTGGTAAAATTTTTCAAATGCCAATGAACAAACTGAGAGAACGTTAT
GATATGTTACACAAATTACTTGAGCTACCAAGAGATGATCACAGAGTTGAAGATTGTTCT
GGTGGACAGATGAGACGAGTATCATTCGCAGCTGCCATGATCCACGAGCCAGACCTACTG
ATCCTCGATGAACCGACAGTTGGCCTTGATCCAATACTCAGAGAGAAAATTTGGAATTTT
ATGCTCAATGTTACACGAACGAGTAAACTTTCAATCATCATCACAACGCACTATATCGAT
GAAGCAAAACAGGCAGATTGCTGTGGTTTAATGCGAAACGGAATTTTATTAGCCGAAGAT
ACGCCAACAAATATTATAAGTCGTCACGAGGTTGATAACCTTGAGGAAGCATTCCTAAAA
CTCTGCATGCGACGTGGTGCTTCAGAAGATGCTGTACAGAATGATGCAATACAAGGAAAC
GAAAGTAGTAGTAGAAATATTGAAAGAATGGATAATTTAGAAATGATAGAACGACCACAC
GAAAATAAATCTGCTACCACAAATTCAATAAATCACAATAACAACATTCAAAATCAAAAT
CATACGACTAGTCAAGAGCAACAGCAGCAACCACAATTATTTAAGCGTAAAAAATATGCT
TGGTCAACCATTCGGGCGCTTTTTACAAAAAATTATTTGCAAATGAAACGACAGCCCGCT
GGAGTAACTTTCATGGTAATCGTTCCAATCCTTCAAATTATATTTTTCTACCTCGCAATA
GGTGGAAATCCCATTGGACTAAAATTTGGTGTTGTAGACGATGAGGTGAATTACAATGAC
TGTTTCAATTCATCACTTATTACAACAATTGCACATGATGACTCTTGTGATTTACATAAA
ATTTCATGTCGATTCATTCATGAGTTTGATGATTCTGTGGCCATTAAGCAGCACTATAAA
ACATTTGATGAAGCATTTCATGATGCAAAAAGAGGAAAAATTATTGGTTTCATGTATTTT
GCGAGTAATTTTACTGAATCATTAGACACAGTTCAACGTGAAGGACGAGATGCAGATGAT
GGCTCAGCTGACAACAGTAGAATACAAATTTATATGGATCAATCAGATTTACAACTCACT
TTCTTTTTACAATCGAAATTTTATCAAATTTTCAAAAATTTCACACAACACATGATGGCC
GATTGCAATTTACCACTAAAATTAGGCAATGTGCCTGTTAATTTTGAAAAACCAATTTAT
GGCAGTTACGACACTGATTTTAAGCATTCGATGGCACCGCCTATGATCATGGTCATGATG
TTTTATATTGCTGCCGGATTGACTGTTGCCATTTTTATTGCCGATAGAAAGGAGGGTTTT
TGGAATCGAACACTTTTAGCTGGTGTAACACTTAAAGAAATGATGCTTGTTCATATTCTT
ACTCATTCGGTTGTGTTAATTCTTCAACTACTTGAAACAATTTTCCTTATAGCATTTGTA
TTTGGTGCTGAAAATAAGGGCTCAAATATTGCAGTACTTTTTATGCTTATGATGCTCGCT
TACTCGGGAATGTTCTTTGGCATGCTTCTGTCAGTTGAATGCAATGATCTTCGTGAAGCT
AACTTTGTGTTGACTGGCATTGCTACACCGATGGTCGTGTTAGCTGGCATGTTTTGGCCA
TTACAAGGAATGCCAATGTTTTTGCAATATGTTTCATATTGTATGCCATTTACACTACCA
TCAATAGCCGTTCGTAACATAATGATGAAGGGATACTCATTTTTTGATCCATCAGTGCTA
ATTGCAGCTGCAATTGTGACTGGTTGGGCATTCTTTGCAATATTATTAGGTCTGCAGGGT
CTTAAGCGGAAAAAATATAGTCGAAATACTTAG
>g4690.t1 Gene=g4690 Length=730
MHAVEVRNAYKYYGKAKDPKIVLNKLNMTVSPGSIYGLMGASGCGKTTLLSCIIGMIGLD
GGEITALGHKTKANEIQKAGHRIGYMPQETALIGELTIKETIYYFGKIFQMPMNKLRERY
DMLHKLLELPRDDHRVEDCSGGQMRRVSFAAAMIHEPDLLILDEPTVGLDPILREKIWNF
MLNVTRTSKLSIIITTHYIDEAKQADCCGLMRNGILLAEDTPTNIISRHEVDNLEEAFLK
LCMRRGASEDAVQNDAIQGNESSSRNIERMDNLEMIERPHENKSATTNSINHNNNIQNQN
HTTSQEQQQQPQLFKRKKYAWSTIRALFTKNYLQMKRQPAGVTFMVIVPILQIIFFYLAI
GGNPIGLKFGVVDDEVNYNDCFNSSLITTIAHDDSCDLHKISCRFIHEFDDSVAIKQHYK
TFDEAFHDAKRGKIIGFMYFASNFTESLDTVQREGRDADDGSADNSRIQIYMDQSDLQLT
FFLQSKFYQIFKNFTQHMMADCNLPLKLGNVPVNFEKPIYGSYDTDFKHSMAPPMIMVMM
FYIAAGLTVAIFIADRKEGFWNRTLLAGVTLKEMMLVHILTHSVVLILQLLETIFLIAFV
FGAENKGSNIAVLFMLMMLAYSGMFFGMLLSVECNDLREANFVLTGIATPMVVLAGMFWP
LQGMPMFLQYVSYCMPFTLPSIAVRNIMMKGYSFFDPSVLIAAAIVTGWAFFAILLGLQG
LKRKKYSRNT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 22 | g4690.t1 | CDD | cd03230 | ABC_DR_subfamily_A | 4 | 216 | 3.60026E-54 |
| 6 | g4690.t1 | Gene3D | G3DSA:3.40.50.300 | - | 1 | 287 | 1.3E-56 |
| 3 | g4690.t1 | PANTHER | PTHR43038 | ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1 | 1 | 725 | 5.8E-265 |
| 4 | g4690.t1 | PANTHER | PTHR43038:SF2 | RH61964P | 1 | 725 | 5.8E-265 |
| 2 | g4690.t1 | Pfam | PF00005 | ABC transporter | 23 | 166 | 2.2E-29 |
| 1 | g4690.t1 | Pfam | PF12698 | ABC-2 family transporter protein | 344 | 713 | 8.3E-29 |
| 14 | g4690.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 339 | - |
| 21 | g4690.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 340 | 360 | - |
| 8 | g4690.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 361 | 534 | - |
| 18 | g4690.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 535 | 554 | - |
| 11 | g4690.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 555 | 573 | - |
| 19 | g4690.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 574 | 603 | - |
| 10 | g4690.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 604 | 609 | - |
| 16 | g4690.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 610 | 630 | - |
| 12 | g4690.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 631 | 641 | - |
| 15 | g4690.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 642 | 660 | - |
| 9 | g4690.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 661 | 666 | - |
| 20 | g4690.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 667 | 687 | - |
| 13 | g4690.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 688 | 698 | - |
| 17 | g4690.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 699 | 718 | - |
| 7 | g4690.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 719 | 730 | - |
| 29 | g4690.t1 | ProSitePatterns | PS00211 | ABC transporters family signature. | 139 | 153 | - |
| 32 | g4690.t1 | ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 4 | 238 | 19.034 |
| 31 | g4690.t1 | ProSiteProfiles | PS51012 | ABC transporter integral membrane type-2 domain profile. | 488 | 724 | 13.576 |
| 30 | g4690.t1 | SMART | SM00382 | AAA_5 | 32 | 236 | 3.9E-10 |
| 5 | g4690.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 3 | 230 | 3.26E-52 |
| 27 | g4690.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 340 | 362 | - |
| 26 | g4690.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 531 | 553 | - |
| 28 | g4690.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 579 | 601 | - |
| 25 | g4690.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 611 | 633 | - |
| 24 | g4690.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 640 | 662 | - |
| 23 | g4690.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 699 | 721 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055085 | transmembrane transport | BP |
| GO:0005524 | ATP binding | MF |
| GO:0016021 | integral component of membrane | CC |
| GO:0043190 | ATP-binding cassette (ABC) transporter complex | CC |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01990 (ABC-2 type transport system ATP-binding protein)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed