General information for g4690.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ABC transporter G family member 23.
Parent gene
- The parent gene g4690 is located on chr_2: 4219107..4223647 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4690 | g4690.t2 | isoform | g4690.t2 | 4219107 | 4223647 |
| chr_2 | g4690 | g4690.t2 | exon | g4690.t2.exon1 | 4219107 | 4220417 |
| chr_2 | g4690 | g4690.t2 | cds | g4690.t2.CDS1 | 4219564 | 4220417 |
| chr_2 | g4690 | g4690.t2 | exon | g4690.t2.exon2 | 4220655 | 4221240 |
| chr_2 | g4690 | g4690.t2 | cds | g4690.t2.CDS2 | 4220655 | 4221240 |
| chr_2 | g4690 | g4690.t2 | exon | g4690.t2.exon3 | 4221352 | 4221719 |
| chr_2 | g4690 | g4690.t2 | cds | g4690.t2.CDS3 | 4221352 | 4221719 |
| chr_2 | g4690 | g4690.t2 | exon | g4690.t2.exon4 | 4223431 | 4223647 |
| chr_2 | g4690 | g4690.t2 | cds | g4690.t2.CDS4 | 4223431 | 4223647 |
| chr_2 | g4690 | g4690.t2 | TTS | g4690.t2 | 4223777 | 4223777 |
| chr_2 | g4690 | g4690.t2 | TSS | g4690.t2 | NA | NA |
Sequences
>g4690.t2 Gene=g4690 Length=2482
ATGCATGCAGTTGAGGTTCGAAATGCTTACAAATATTATGGGAAGGCGAAAGATCCAAAG
ATTGTCTTAAACAAACTAAATATGACAGTCTCGCCTGGCTCAATGTAAGTCATAAACTTT
AGTCATATATTCATTCATTAAAATATATCTATAAAGTGTTTAAGCAAATGTTATCTTCAC
CTTCAACACTTTTCAACTTTGCTTCATCGTTTAAAAAATTCCTTAACATCATGAATTTTT
TTTTTCTCATCTTCTCTCTAACAGTTACGGACTCATGGGAGCAAGCGGTAAATGTTTTAA
CAAGTTATTTTTCAATAGTATAATAATCAAATAGCCAATTGTGATTTTCTTATGTGTCGG
CTATTTGAATCTTTGTAAACAAAACATTTATTTATATAAAAATTGTCTAATATTAATAGG
ATGTGGGAAGACAACACTTTTATCGTGTATCATTGGCATGATTGGTCTTGATGGTGGTGA
AATCACAGCACTTGGTCATAAGACGAAAGCGAATGAAATACAAAAGGCGGGTCATCGTAT
TGGCTATATGCCACAAGAGACAGCATTAATTGGTGAATTAACGATCAAAGAAACAATTTA
TTATTTTGGTAAAATTTTTCAAATGCCAATGAACAAACTGAGAGAACGTTATGATATGTT
ACACAAATTACTTGAGCTACCAAGAGATGATCACAGAGTTGAAGATTGTTCTGGTGGACA
GATGAGACGAGTATCATTCGCAGCTGCCATGATCCACGAGCCAGACCTACTGATCCTCGA
TGAACCGACAGTTGGCCTTGATCCAATACTCAGAGAGAAAATTTGGAATTTTATGCTCAA
TGTTACACGAACGAGTAAACTTTCAATCATCATCACAACGCACTATATCGATGAAGCAAA
ACAGGCAGATTGCTGTGGTTTAATGCGAAACGGAATTTTATTAGCCGAAGATACGCCAAC
AAATATTATAAGTCGTCACGAGGTTGATAACCTTGAGGAAGCATTCCTAAAACTCTGCAT
GCGACGTGGTGCTTCAGAAGATGCTGTACAGAATGATGCAATACAAGGAAACGAAAGTAG
TAGTAGAAATATTGAAAGAATGGATAATTTAGAAATGATAGAACGACCACACGAAAATAA
ATCTGCTACCACAAATTCAATAAATCACAATAACAACATTCAAAATCAAAATCATACGAC
TAGTCAAGAGCAACAGCAGCAACCACAATTATTTAAGCGTAAAAAATATGCTTGGTCAAC
CATTCGGGCGCTTTTTACAAAAAATTATTTGCAAATGAAACGACAGCCCGCTGGAGTAAC
TTTCATGGTAATCGTTCCAATCCTTCAAATTATATTTTTCTACCTCGCAATAGGTGGAAA
TCCCATTGGACTAAAATTTGGTGTTGTAGACGATGAGGTGAATTACAATGACTGTTTCAA
TTCATCACTTATTACAACAATTGCACATGATGACTCTTGTGATTTACATAAAATTTCATG
TCGATTCATTCATGAGTTTGATGATTCTGTGGCCATTAAGCAGCACTATAAAACATTTGA
TGAAGCATTTCATGATGCAAAAAGAGGAAAAATTATTGGTTTCATGTATTTTGCGAGTAA
TTTTACTGAATCATTAGACACAGTTCAACGTGAAGGACGAGATGCAGATGATGGCTCAGC
TGACAACAGTAGAATACAAATTTATATGGATCAATCAGATTTACAACTCACTTTCTTTTT
ACAATCGAAATTTTATCAAATTTTCAAAAATTTCACACAACACATGATGGCCGATTGCAA
TTTACCACTAAAATTAGGCAATGTGCCTGTTAATTTTGAAAAACCAATTTATGGCAGTTA
CGACACTGATTTTAAGCATTCGATGGCACCGCCTATGATCATGGTCATGATGTTTTATAT
TGCTGCCGGATTGACTGTTGCCATTTTTATTGCCGATAGAAAGGAGGGTTTTTGGAATCG
AACACTTTTAGCTGGTGTAACACTTAAAGAAATGATGCTTGTTCATATTCTTACTCATTC
GGTTGTGTTAATTCTTCAACTACTTGAAACAATTTTCCTTATAGCATTTGTATTTGGTGC
TGAAAATAAGGGCTCAAATATTGCAGTACTTTTTATGCTTATGATGCTCGCTTACTCGGG
AATGTTCTTTGGCATGCTTCTGTCAGTTGAATGCAATGATCTTCGTGAAGCTAACTTTGT
GTTGACTGGCATTGCTACACCGATGGTAATGAACTTAATTGATTTGCCATTACAAGGAAT
GCCAATGTTTTTGCAATATGTTTCATATTGTATGCCATTTACACTACCATCAATAGCCGT
TCGTAACATAATGATGAAGGGATACTCATTTTTTGATCCATCAGTGCTAATTGCAGCTGC
AATTGTGACTGGTTGGGCATTCTTTGCAATATTATTAGGTCTGCAGGGTCTTAAGCGGAA
AAAATATAGTCGAAATACTTAG
>g4690.t2 Gene=g4690 Length=674
MIGLDGGEITALGHKTKANEIQKAGHRIGYMPQETALIGELTIKETIYYFGKIFQMPMNK
LRERYDMLHKLLELPRDDHRVEDCSGGQMRRVSFAAAMIHEPDLLILDEPTVGLDPILRE
KIWNFMLNVTRTSKLSIIITTHYIDEAKQADCCGLMRNGILLAEDTPTNIISRHEVDNLE
EAFLKLCMRRGASEDAVQNDAIQGNESSSRNIERMDNLEMIERPHENKSATTNSINHNNN
IQNQNHTTSQEQQQQPQLFKRKKYAWSTIRALFTKNYLQMKRQPAGVTFMVIVPILQIIF
FYLAIGGNPIGLKFGVVDDEVNYNDCFNSSLITTIAHDDSCDLHKISCRFIHEFDDSVAI
KQHYKTFDEAFHDAKRGKIIGFMYFASNFTESLDTVQREGRDADDGSADNSRIQIYMDQS
DLQLTFFLQSKFYQIFKNFTQHMMADCNLPLKLGNVPVNFEKPIYGSYDTDFKHSMAPPM
IMVMMFYIAAGLTVAIFIADRKEGFWNRTLLAGVTLKEMMLVHILTHSVVLILQLLETIF
LIAFVFGAENKGSNIAVLFMLMMLAYSGMFFGMLLSVECNDLREANFVLTGIATPMVMNL
IDLPLQGMPMFLQYVSYCMPFTLPSIAVRNIMMKGYSFFDPSVLIAAAIVTGWAFFAILL
GLQGLKRKKYSRNT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g4690.t2 | Gene3D | G3DSA:3.40.50.300 | - | 1 | 193 | 1.6E-36 |
| 3 | g4690.t2 | PANTHER | PTHR43038 | ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1 | 4 | 669 | 1.7E-225 |
| 4 | g4690.t2 | PANTHER | PTHR43038:SF2 | RH61964P | 4 | 669 | 1.7E-225 |
| 2 | g4690.t2 | Pfam | PF00005 | ABC transporter | 6 | 111 | 3.3E-14 |
| 1 | g4690.t2 | Pfam | PF12698 | ABC-2 family transporter protein | 289 | 657 | 7.3E-25 |
| 19 | g4690.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 284 | - |
| 28 | g4690.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 285 | 305 | - |
| 16 | g4690.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 306 | 479 | - |
| 23 | g4690.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 480 | 499 | - |
| 21 | g4690.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 500 | 518 | - |
| 25 | g4690.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 519 | 548 | - |
| 17 | g4690.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 549 | 554 | - |
| 26 | g4690.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 555 | 575 | - |
| 18 | g4690.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 576 | 586 | - |
| 24 | g4690.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 587 | 605 | - |
| 14 | g4690.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 606 | 611 | - |
| 22 | g4690.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 612 | 631 | - |
| 20 | g4690.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 632 | 642 | - |
| 27 | g4690.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 643 | 662 | - |
| 15 | g4690.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 663 | 674 | - |
| 12 | g4690.t2 | ProSitePatterns | PS00211 | ABC transporters family signature. | 84 | 98 | - |
| 11 | g4690.t2 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 4 | 173 | 7.23E-33 |
| 8 | g4690.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 285 | 307 | - |
| 5 | g4690.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 476 | 498 | - |
| 10 | g4690.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 524 | 546 | - |
| 7 | g4690.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 556 | 578 | - |
| 6 | g4690.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 585 | 607 | - |
| 9 | g4690.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 643 | 665 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed