General information for g4691.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ABC transporter G family member 23.
Parent gene
- The parent gene g4691 is located on chr_2: 4225500..4228372 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4691 | g4691.t1 | TSS | g4691.t1 | 4224028 | 4224028 |
| chr_2 | g4691 | g4691.t1 | isoform | g4691.t1 | 4225500 | 4228372 |
| chr_2 | g4691 | g4691.t1 | exon | g4691.t1.exon1 | 4225500 | 4225603 |
| chr_2 | g4691 | g4691.t1 | cds | g4691.t1.CDS1 | 4225500 | 4225603 |
| chr_2 | g4691 | g4691.t1 | exon | g4691.t1.exon2 | 4225669 | 4225691 |
| chr_2 | g4691 | g4691.t1 | cds | g4691.t1.CDS2 | 4225669 | 4225691 |
| chr_2 | g4691 | g4691.t1 | exon | g4691.t1.exon3 | 4225747 | 4226587 |
| chr_2 | g4691 | g4691.t1 | cds | g4691.t1.CDS3 | 4225747 | 4226587 |
| chr_2 | g4691 | g4691.t1 | exon | g4691.t1.exon4 | 4226902 | 4226998 |
| chr_2 | g4691 | g4691.t1 | cds | g4691.t1.CDS4 | 4226902 | 4226998 |
| chr_2 | g4691 | g4691.t1 | exon | g4691.t1.exon5 | 4227056 | 4227932 |
| chr_2 | g4691 | g4691.t1 | cds | g4691.t1.CDS5 | 4227056 | 4227932 |
| chr_2 | g4691 | g4691.t1 | exon | g4691.t1.exon6 | 4228167 | 4228372 |
| chr_2 | g4691 | g4691.t1 | cds | g4691.t1.CDS6 | 4228167 | 4228372 |
| chr_2 | g4691 | g4691.t1 | TTS | g4691.t1 | 4228459 | 4228459 |
Sequences
>g4691.t1 Gene=g4691 Length=2148
ATGAATACTGTCGAGGTGCGAAATGCTGTCAAATATTATGGATCAGGCAACGATCCATTT
ATGATTCTTAATAAGCTCAATATGACTGTTCCACCTGGGTCAATATATGCTCTATTAGGT
GCTTCAGGATGTGGCAAAACAACTTTGCTCTCATGCATTCTTGGAATGATTCCATTGGAT
GATGGAGAAATTTCAGTATTTGGTAATGTTACAACAAAATATGCCACAAAAGTGAATGGT
TCGAGAATTGGTTATATGCCACAGGAAATGGCATTAGTTGGTGAGCTAACTGTCAAAGAA
ACAATTTATTATTTTGGTAAAATATTTTTAATGGACATTGATAAGTTAAGAGATCGTTAT
GACATGCTACATAAATTACTTGAGCTGCCAAGAGGAGATCAACGAATTGAAACATGTTCT
GGTGGACAGAAAAGACGAGTTTCATTTGCAGCTGCCATGATCCATGAGCCAGATTTATTA
ATTCTTGATGAGCCGACAGTTGGCCTCGATCCATTGCTCAGAGAAAAAATTTGGAGTTTT
ATGCTTGATGTTACAAGCACAAGTAAACTTTCCATAATTATTACAACACATTACATTGAA
GAAGCACGACAAGCAAAATGTGTTGGTTTAATGCGAAATGGTGTTCTGCTGGCAGAAGAT
AAACCTATGAATATCGTAAATCAAAATAATGTTGAGAATCTTGAAGAAGCATTTCTTGCT
TTATGCTTAAAACGTGGTGTTTCTGAGTATGCTGGAGCACTCACATATATTGAAACAAAT
GGCACGAACAACAATATTTATAATACAAACAATCTTGAAATGAATGCAAATCGAAAACAC
ACATCAAAATACAAGAACAAAAATGTGTTTGCAAGTGTTTCAACCGAAAGCAGAAGCAAC
AACTTACGATGGCCAATCGTCAAAACACTGTTTATAAAAGTTTGGACACAGTTGAAACGA
CAACCAGCTGCTCTCGTGTTAATTACATTCTTACCGATCATTCAACTCTTTTTCTTTTAT
CATGCATGTGGTGGCAATCCAAAAGGACTACAATTAGCTATAGTTAATAATGAAATTGAT
GATTATGAAACAACATGTAATCGAAGCACATTAATTAGTACATATCCTCATGATTATACG
TGTGATTTGCATCTCATATCATGCAGATTCCTCGATGAACTCACAGATGAAACAGCAATA
AAAGTTTTTTTCTCTTCATTTGATGAAGCATGGAAAGCAGCAAAACGTGGAGAATATATT
GGTATAATTGAAATATCGAGAAATTTTACAGAGGCACTAGAAATTGTTAGAAAAAGACCT
GAAGAAGCAACTGAAGGGATAATACAAAGCAGCAAGATCAAAGTGTATCTAGATCAAGCT
GATTTACAATTAACTTTTTTCCTTCAAAGGAAAATTTATGAAGTTTATACAAATTATACT
CAGAATGTTCTCAGAGATTGTAAAATGCCCATAAAATTGGACAACATTCCAATGGATTTT
TCAGAATCACTTTTTGGTTCAATCGATTCTGATTTTAAACATACAATGATGCCGGCATTC
ACAATGTTAGTTGTATTTGTACTTTCATCTGGTCTGACACTTAGTGGGATCATTTTAGAA
CGAAAAGAAGGCTTTTGGAACAGAACATTGCTTGCTGGAGTTTCAACAATCGAAATCTTA
TCAGCTTACATCATAATCAATTTCATAATTGTCATTATGCAGTTATTTGAAGTTCTTTTC
CTATTAACATTCATTTATGGAACATATTACCATGGATCTTATATGATTGTTATGATGATG
CTCGCTATTTTGGGATGTAGTGGTATTAATTTTGGATTATGGATTTCATGTCTTTGTTCT
GAACTAATGCAAGCTAATTTATTAATGTCTGGGATTACTCAGCCATTGACCGTGCTAAGT
GGAATGATTTGGCCGGTTGAAGGAATGCCAATCGTATTAAGAATAATTTCTTATGCAATG
CCAACGACGATACCTAGTCGTGCAATGCGTGAAGTGATAGAGAAAAAATACACACTTACG
CATCCAAATGTGCTGTTAGCATTTGGCAATCTTTTTGCTTGGTTTTTCATCACTTTATAT
TTAGGAATATCAGCAGTTAAAAGAAGCAAATACAGTCGTAACACGTAA
>g4691.t1 Gene=g4691 Length=715
MNTVEVRNAVKYYGSGNDPFMILNKLNMTVPPGSIYALLGASGCGKTTLLSCILGMIPLD
DGEISVFGNVTTKYATKVNGSRIGYMPQEMALVGELTVKETIYYFGKIFLMDIDKLRDRY
DMLHKLLELPRGDQRIETCSGGQKRRVSFAAAMIHEPDLLILDEPTVGLDPLLREKIWSF
MLDVTSTSKLSIIITTHYIEEARQAKCVGLMRNGVLLAEDKPMNIVNQNNVENLEEAFLA
LCLKRGVSEYAGALTYIETNGTNNNIYNTNNLEMNANRKHTSKYKNKNVFASVSTESRSN
NLRWPIVKTLFIKVWTQLKRQPAALVLITFLPIIQLFFFYHACGGNPKGLQLAIVNNEID
DYETTCNRSTLISTYPHDYTCDLHLISCRFLDELTDETAIKVFFSSFDEAWKAAKRGEYI
GIIEISRNFTEALEIVRKRPEEATEGIIQSSKIKVYLDQADLQLTFFLQRKIYEVYTNYT
QNVLRDCKMPIKLDNIPMDFSESLFGSIDSDFKHTMMPAFTMLVVFVLSSGLTLSGIILE
RKEGFWNRTLLAGVSTIEILSAYIIINFIIVIMQLFEVLFLLTFIYGTYYHGSYMIVMMM
LAILGCSGINFGLWISCLCSELMQANLLMSGITQPLTVLSGMIWPVEGMPIVLRIISYAM
PTTIPSRAMREVIEKKYTLTHPNVLLAFGNLFAWFFITLYLGISAVKRSKYSRNT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 20 | g4691.t1 | CDD | cd03230 | ABC_DR_subfamily_A | 4 | 216 | 2.68128E-56 |
| 6 | g4691.t1 | Gene3D | G3DSA:3.40.50.300 | - | 1 | 287 | 2.7E-56 |
| 3 | g4691.t1 | PANTHER | PTHR43038 | ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1 | 1 | 708 | 5.2E-230 |
| 4 | g4691.t1 | PANTHER | PTHR43038:SF2 | RH61964P | 1 | 708 | 5.2E-230 |
| 2 | g4691.t1 | Pfam | PF00005 | ABC transporter | 23 | 166 | 2.6E-28 |
| 1 | g4691.t1 | Pfam | PF12698 | ABC-2 family transporter protein | 325 | 701 | 3.6E-25 |
| 10 | g4691.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 322 | - |
| 17 | g4691.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 323 | 342 | - |
| 11 | g4691.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 343 | 515 | - |
| 19 | g4691.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 516 | 539 | - |
| 8 | g4691.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 540 | 559 | - |
| 15 | g4691.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 560 | 586 | - |
| 13 | g4691.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 587 | 591 | - |
| 16 | g4691.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 592 | 615 | - |
| 9 | g4691.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 616 | 626 | - |
| 14 | g4691.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 627 | 644 | - |
| 12 | g4691.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 645 | 683 | - |
| 18 | g4691.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 684 | 703 | - |
| 7 | g4691.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 704 | 715 | - |
| 26 | g4691.t1 | ProSitePatterns | PS00211 | ABC transporters family signature. | 139 | 153 | - |
| 29 | g4691.t1 | ProSiteProfiles | PS50893 | ATP-binding cassette, ABC transporter-type domain profile. | 4 | 238 | 19.521 |
| 28 | g4691.t1 | ProSiteProfiles | PS51012 | ABC transporter integral membrane type-2 domain profile. | 481 | 709 | 11.276 |
| 27 | g4691.t1 | SMART | SM00382 | AAA_5 | 32 | 222 | 2.3E-11 |
| 5 | g4691.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 4 | 230 | 7.67E-53 |
| 25 | g4691.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 517 | 539 | - |
| 24 | g4691.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 559 | 581 | - |
| 23 | g4691.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 596 | 618 | - |
| 22 | g4691.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 625 | 644 | - |
| 21 | g4691.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 684 | 706 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055085 | transmembrane transport | BP |
| GO:0005524 | ATP binding | MF |
| GO:0016021 | integral component of membrane | CC |
| GO:0043190 | ATP-binding cassette (ABC) transporter complex | CC |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
- This transcript has been annotated with K13926 (ribosome-dependent ATPase)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed