General information for g4726.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Inactive hydroxysteroid dehydrogenase-like protein 1.
Parent gene
- The parent gene g4726 is located on chr_2: 4395932..4397107 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4726 | g4726.t1 | isoform | g4726.t1 | 4395932 | 4397107 |
| chr_2 | g4726 | g4726.t1 | exon | g4726.t1.exon1 | 4395932 | 4396091 |
| chr_2 | g4726 | g4726.t1 | cds | g4726.t1.CDS1 | 4395932 | 4396091 |
| chr_2 | g4726 | g4726.t1 | exon | g4726.t1.exon2 | 4396141 | 4396263 |
| chr_2 | g4726 | g4726.t1 | cds | g4726.t1.CDS2 | 4396141 | 4396263 |
| chr_2 | g4726 | g4726.t1 | exon | g4726.t1.exon3 | 4396317 | 4396673 |
| chr_2 | g4726 | g4726.t1 | cds | g4726.t1.CDS3 | 4396317 | 4396673 |
| chr_2 | g4726 | g4726.t1 | exon | g4726.t1.exon4 | 4396732 | 4396937 |
| chr_2 | g4726 | g4726.t1 | cds | g4726.t1.CDS4 | 4396732 | 4396937 |
| chr_2 | g4726 | g4726.t1 | exon | g4726.t1.exon5 | 4397003 | 4397107 |
| chr_2 | g4726 | g4726.t1 | cds | g4726.t1.CDS5 | 4397003 | 4397107 |
| chr_2 | g4726 | g4726.t1 | TSS | g4726.t1 | NA | NA |
| chr_2 | g4726 | g4726.t1 | TTS | g4726.t1 | NA | NA |
Sequences
>g4726.t1 Gene=g4726 Length=951
ATGCTCTCAACATTTCTGCAATTTATTGGTGCTTACGCATTAATTTTATACTTAATTGAC
AATTTTAAATCGCCATTTAAAATTTTTCTTTGTAATTTGTGTGAATTTTTGAAGATTACT
AAGAAAAAAAGTTTAAGTGAGAATTTTGGAGAATGGGCCGTTGTAACTGGATCAACAGAT
GGAATTGGAAGACAATATGCAAAAGAATTAGCAAAAAATGGCATGAACATCATTTTAATA
TCAAGATCAGAATCAAAATTGATTGAAGTAGCAAAGGAAATTGAATCAACATATTCAGTA
AAAACAAAATACATTGTAGCAGATTTTGGCATAGGCAGAGAAATTTATGGCAAAATAAAA
CAAGAACTTTCATCATTTGATATTGGAATTTTAGTCAATAATGTTGGAACTTTTCATGAT
TATCCCGAATATTTTGATAAAGTTTCTGATGATGTTTTATGGAAAATAATCAATGTAAAT
GTTGCAGCAATGACAATATTAACGAGATTTATTGTTCCACAAATGAAAAAGAATAAACGT
GGAATAATTGTGAACGTTAGCTCAGGTGCAGAACATCAACCAACTCCATTAGGTTCAATT
TATTGTGCTAGCAAAGTTTATGTGAAATTTTTCACTTTAGCAATGCAACATGAACTCAAA
GAATTTAATGTCCACTGCCAACTTCTTGCTCCTATGTTTGTAAAAACTCAATTAAACAAA
TATTCTGATTATTTATCAAAAGAAGAAAACCTTTTTGTCATTGGTGTTGAATCTTATGCT
CAACAATCAGTTGCAACCTTGGGAAAAAGTTTAAGAACGACTGGCTGTTGGAAGCATGGA
ATACAAGTTGCTATTGGAAATATCATGCCGCAATTTATCAGAACATTTTTCGTGTTTAAA
CTTGCTAAGAAATTTCGTAATGATTATATTCAAAAGCATAAATTAGAATAA
>g4726.t1 Gene=g4726 Length=316
MLSTFLQFIGAYALILYLIDNFKSPFKIFLCNLCEFLKITKKKSLSENFGEWAVVTGSTD
GIGRQYAKELAKNGMNIILISRSESKLIEVAKEIESTYSVKTKYIVADFGIGREIYGKIK
QELSSFDIGILVNNVGTFHDYPEYFDKVSDDVLWKIINVNVAAMTILTRFIVPQMKKNKR
GIIVNVSSGAEHQPTPLGSIYCASKVYVKFFTLAMQHELKEFNVHCQLLAPMFVKTQLNK
YSDYLSKEENLFVIGVESYAQQSVATLGKSLRTTGCWKHGIQVAIGNIMPQFIRTFFVFK
LAKKFRNDYIQKHKLE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 22 | g4726.t1 | CDD | cd05356 | 17beta-HSD1_like_SDR_c | 50 | 293 | 3.50583E-110 |
| 13 | g4726.t1 | Gene3D | G3DSA:3.40.50.720 | - | 45 | 277 | 1.3E-49 |
| 2 | g4726.t1 | PANTHER | PTHR43899:SF9 | MIP25013P-RELATED | 2 | 314 | 1.1E-118 |
| 3 | g4726.t1 | PANTHER | PTHR43899 | RH59310P | 2 | 314 | 1.1E-118 |
| 21 | g4726.t1 | PIRSF | PIRSF000126 | 11-beta-HSD1 | 3 | 312 | 3.1E-97 |
| 10 | g4726.t1 | PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 52 | 69 | 3.1E-14 |
| 6 | g4726.t1 | PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 126 | 137 | 3.3E-5 |
| 11 | g4726.t1 | PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 126 | 137 | 3.1E-14 |
| 9 | g4726.t1 | PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 175 | 191 | 3.1E-14 |
| 4 | g4726.t1 | PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 181 | 189 | 3.3E-5 |
| 5 | g4726.t1 | PRINTS | PR00080 | Short-chain dehydrogenase/reductase (SDR) superfamily signature | 201 | 220 | 3.3E-5 |
| 8 | g4726.t1 | PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 201 | 220 | 3.1E-14 |
| 7 | g4726.t1 | PRINTS | PR00081 | Glucose/ribitol dehydrogenase family signature | 222 | 239 | 3.1E-14 |
| 1 | g4726.t1 | Pfam | PF00106 | short chain dehydrogenase | 52 | 241 | 7.2E-42 |
| 16 | g4726.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 13 | - |
| 17 | g4726.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 1 | - |
| 18 | g4726.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 2 | 9 | - |
| 20 | g4726.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 10 | 13 | - |
| 15 | g4726.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 14 | 151 | - |
| 19 | g4726.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 152 | 172 | - |
| 14 | g4726.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 173 | 316 | - |
| 23 | g4726.t1 | ProSitePatterns | PS00061 | Short-chain dehydrogenases/reductases family signature. | 188 | 216 | - |
| 12 | g4726.t1 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 50 | 306 | 3.02E-48 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055114 | NA | NA |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed