General information for g4791.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Kelch-like protein 17.
Parent gene
- The parent gene g4791 is located on chr_2: 4991936..4992659 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4791 | g4791.t4 | isoform | g4791.t4 | 4989116 | 4990917 |
| chr_2 | g4791 | g4791.t4 | exon | g4791.t4.exon1 | 4989116 | 4990512 |
| chr_2 | g4791 | g4791.t4 | cds | g4791.t4.CDS1 | 4989996 | 4990512 |
| chr_2 | g4791 | g4791.t4 | exon | g4791.t4.exon2 | 4990775 | 4990917 |
| chr_2 | g4791 | g4791.t4 | cds | g4791.t4.CDS2 | 4990775 | 4990863 |
| chr_2 | g4791 | g4791.t4 | TSS | g4791.t4 | NA | NA |
| chr_2 | g4791 | g4791.t4 | TTS | g4791.t4 | NA | NA |
Sequences
>g4791.t4 Gene=g4791 Length=1540
AGTAATTAAATTTATGAAGAAGAAGAAGAAGCACTTTCTTATGTATCCAGACACACACGC
AACATATTCTAATTATTTATAAAAAAACAGAAATGAAGTCCAGAATATTACGAATACACA
CACACAACACACACCTACATACAAGTAGAACTTATCTATTAATTCAAGCAACATGTTATA
AATAATCAAAAAAAAATAATATGACGATTAAAGAGAAGCAGAGGTTTCTTTGAAATTATT
ATTCTATTAAAATGAAATTTAGCCGATAATAAAATGAAATATTGTACGAGATTTTTCTTT
ATAGATACAATTACAATAAACAAATTTAAATTAAAATTTTATTTTTGAGTGGTTTTATTT
TCACTTGAGTTGTTGGCATCCTTTAAGCATTTTTCGAGGTACAACTTTAGTTTTTGTTGA
TTGAAGAAAATTTTTGATAAAAAAAAAACAATTTTTTTTATTTTAATCACTTGCGATTTG
ATAATTTGTCTAGTATTATTGATAAAACAGTATTTAAAGTGAACAACTCTAATATGATAT
AATTAAAACATGACATAAAAACCAAAAAGTGATGATAAATGATATTGAGAAAAAGTGGGG
AGTTGTCTGTATAGAAAATATTTTCATTGTGCAAAATTAAAAATTAAAAGAAATGCCACA
AAACGAGTAGAATACAAATACTATTGTTTCAACACCAGAATCGCCTCTCATCAGTCTATC
AAATAGTTATTACACAAATTTTTTTAAAAATCTCAAACTCATTTATGATGATGAGCGATT
TTTTGATGTTGAATTGCATTGTGAAAGTAATGGAAAAGAGCAAAATATCATAAAAGCACA
TAGAATAGTATTATCAGCCTCAAGCCGCTATTTTGATGCAATGTTTGGAAATGATTTCAA
TGAAAATAAGAATAAAATTGTTAAATTTCACTCTATAAGTTATTCGATATTGAAAGAATT
AATTGGATTCATTTATACTGGAAAAATTGAAATAAATCAAGTAAATGTGCAAGAATTATT
AGCAGCAGCTGATATGCTTCAATTGACAGAAGTAGTCGATGGCTGTTCAATGTATTTATG
TCGTGAATTGCATCCTTCTAATGCTTTAGGAATTCTGAGATTTGCTGAGGCACATAATTG
TAAAGAGCTTGCTGAATCTGCACTTTCATTTATTAATTCACATTTTCCTGAAGTCGCAGA
ACAAGATGAAATATTAGAAATCTCATCACAAATGTTTTCACGTCTTATATCATCAGAAAT
GATAAGAGTTGACAGCGAATACCAAGTATTTTCTGCAGCAATGCGTTGGGTCAAGCATGA
AATCAGTAACCGAAAGAGATTTGTTTTTGATATTTTGGCAAATGTTCGCCTGTCTCTCGT
TTCCATGCGATTGATTGAATTTTACCTGGTATACAATAGAATACTCTTCTTAATCATCTT
CATTACGCTTATTTTCCTTTTTCTTTTCAAGGTGTTACTGTATTAAATTCTAAAATTTTT
GTTGTTGGTGGCGAAAGAGGCTCTCAAATATTTGCAAATG
>g4791.t4 Gene=g4791 Length=201
MFGNDFNENKNKIVKFHSISYSILKELIGFIYTGKIEINQVNVQELLAAADMLQLTEVVD
GCSMYLCRELHPSNALGILRFAEAHNCKELAESALSFINSHFPEVAEQDEILEISSQMFS
RLISSEMIRVDSEYQVFSAAMRWVKHEISNRKRFVFDILANVRLSLVSMRLIEFYLVYNR
ILFLIIFITLIFLFLFKVLLY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g4791.t4 | Gene3D | G3DSA:3.30.710.10 | Potassium Channel Kv1.1; Chain A | 1 | 71 | 5.5E-20 |
| 6 | g4791.t4 | Gene3D | G3DSA:1.25.40.420 | - | 72 | 182 | 1.2E-31 |
| 3 | g4791.t4 | PANTHER | PTHR24412 | KELCH PROTEIN | 1 | 167 | 1.6E-46 |
| 4 | g4791.t4 | PANTHER | PTHR24412:SF401 | FI11917P | 1 | 167 | 1.6E-46 |
| 2 | g4791.t4 | Pfam | PF00651 | BTB/POZ domain | 1 | 69 | 7.3E-13 |
| 1 | g4791.t4 | Pfam | PF07707 | BTB And C-terminal Kelch | 76 | 172 | 1.2E-28 |
| 8 | g4791.t4 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 153 | - |
| 11 | g4791.t4 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 154 | 175 | - |
| 10 | g4791.t4 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 176 | 180 | - |
| 12 | g4791.t4 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 181 | 200 | - |
| 9 | g4791.t4 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 201 | 201 | - |
| 15 | g4791.t4 | ProSiteProfiles | PS50097 | BTB domain profile. | 1 | 40 | 9.889 |
| 14 | g4791.t4 | SMART | SM00875 | BACK_2 | 75 | 177 | 8.1E-27 |
| 5 | g4791.t4 | SUPERFAMILY | SSF54695 | POZ domain | 1 | 68 | 1.96E-15 |
| 13 | g4791.t4 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 174 | 196 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
