General information for g48.t10
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Probable cytochrome P450 6a13.
Parent gene
- The parent gene g48 is located on chr_3: 411950..414671 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g48 | g48.t10 | TSS | g48.t10 | 410853 | 410853 |
| chr_3 | g48 | g48.t10 | isoform | g48.t10 | 410889 | 412637 |
| chr_3 | g48 | g48.t10 | exon | g48.t10.exon1 | 410889 | 411239 |
| chr_3 | g48 | g48.t10 | exon | g48.t10.exon2 | 411301 | 411525 |
| chr_3 | g48 | g48.t10 | cds | g48.t10.CDS1 | 411372 | 411525 |
| chr_3 | g48 | g48.t10 | exon | g48.t10.exon3 | 411582 | 411882 |
| chr_3 | g48 | g48.t10 | cds | g48.t10.CDS2 | 411582 | 411882 |
| chr_3 | g48 | g48.t10 | exon | g48.t10.exon4 | 411941 | 412365 |
| chr_3 | g48 | g48.t10 | cds | g48.t10.CDS3 | 411941 | 412365 |
| chr_3 | g48 | g48.t10 | exon | g48.t10.exon5 | 412477 | 412637 |
| chr_3 | g48 | g48.t10 | cds | g48.t10.CDS4 | 412477 | 412544 |
| chr_3 | g48 | g48.t10 | TTS | g48.t10 | 412694 | 412694 |
Sequences
>g48.t10 Gene=g48 Length=1463
ATGGGTTTTGTTTTGACATTAATAATTATTTTAGTAATTTCATTTTATTTTTGGATGAAA
AAACATTTTAATTATTGGAAAAATCGAGGTTTTCTGCAAGTTGATGGATCATTTCCATTA
GGCTCACTTAGTGGTGTTGGAACAAAAATATGTTCGACTGAAAAATATGACTTGATTTAT
AAAGGTTTCAAGGGAAAAGCGTCGGTTGTTGGATTTTATAATTTTTTATCACCAGCAGTT
TTGCCAATTGAACCTGAATTGATTAAAAATATTTTGGTATTAAATTTTGCATCATTTCAT
GATCGTGGTCTTTATTATAATAAGAAAGATGATCCAATGAGTGCTAAGTAACTTTAGAAG
GTCAAGAATGGAAAGAACGTCGTACAAAAATCACCCCATTATTTTCATCAGGAAAGATTA
AAATGATGTTTGAAATAGTCACTGAAATTGGTGATAAATTAGTAAATGCTATAAAAAGAG
AATTGAATGAGTCAACTGAACAAGATATGAGAGTTTGGGCACAAAAATATACAAATGATA
CAATTAGCAATATCGCATTTGGACTCTCTCTTTCTTGTCTTGATGGTGAAAATTTGGAAT
TTTTAAAAAATGGAAAGAGACTTTTTGAGCTTAAACCATGGGAAGTTTTGAAAATTCTTT
TTACATCTGAAATGCCAAAACTTAGTAGATTTCTTCGTTTGAAATTCACTGCTGGAAATA
CTGGAGAATTTTTTCATAAAACTTTTCTTGAAACTTTTAATTATCGTCAAAATAATTCAA
TTGAACGCAATGATTTAGTGTCGTTGTTGTTAAAACTGAAAGATGTTTATACTCTGACAG
AACTTGCAGCTGAAGCATTTTTAGTATACACTGGCGGATTTGAGACAAGTTCAACTTTAA
TAACTTTTGCTCTCTATGAATTTTCATTAAATCAACAAATTCAAGAAAGATTGCGTGATG
AAATAAATTCGGGAATTGAAAATAATGATGGAAAATTGACTTATGAATTATTAAACAGTT
TTAAATATTTAGAAATGGTTATTAATGAAACTCTAAGGAAATATCCACCGCTTTCTAACA
TTTTTCGTAAAACTACCAAAGATTATAAAATTCCTGATGAAGATTTATTGATTTGTAAAG
GAACAGCAGTTATAATTAATACTTATTCATTACATCATGATCCTCAATACTTTTCAAAAC
CTGACAAATTTGATCCGGAAAGGTTTAATGAAGAAAACATTGGAAGTATTAAACCTTATA
CATTTTTGCCATTTGGTAAATATTTAAAAATAAAATATTTGAGGAATGCGATTTGGAATG
ATGCAAACAAAAATAGCAATCACGAAATTGATTTCAAATTTTTCTTTTAAGCCATGTTCA
AAAACAACAATTCCAATGAAATTTAAACCTTCTTCACCATTCATTTGTCCTGTTGATGGA
ATGTTTTTGAGTGTGGAATCATT
>g48.t10 Gene=g48 Length=315
MMFEIVTEIGDKLVNAIKRELNESTEQDMRVWAQKYTNDTISNIAFGLSLSCLDGENLEF
LKNGKRLFELKPWEVLKILFTSEMPKLSRFLRLKFTAGNTGEFFHKTFLETFNYRQNNSI
ERNDLVSLLLKLKDVYTLTELAAEAFLVYTGGFETSSTLITFALYEFSLNQQIQERLRDE
INSGIENNDGKLTYELLNSFKYLEMVINETLRKYPPLSNIFRKTTKDYKIPDEDLLICKG
TAVIINTYSLHHDPQYFSKPDKFDPERFNEENIGSIKPYTFLPFGKYLKIKYLRNAIWND
ANKNSNHEIDFKFFF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g48.t10 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 1 | 286 | 0 |
| 2 | g48.t10 | PANTHER | PTHR24292 | CYTOCHROME P450 | 1 | 286 | 0 |
| 3 | g48.t10 | PANTHER | PTHR24292:SF95 | CYP6A16, ISOFORM B-RELATED | 1 | 286 | 0 |
| 5 | g48.t10 | PRINTS | PR00463 | E-class P450 group I signature | 140 | 157 | 0 |
| 6 | g48.t10 | PRINTS | PR00463 | E-class P450 group I signature | 160 | 186 | 0 |
| 4 | g48.t10 | PRINTS | PR00463 | E-class P450 group I signature | 246 | 270 | 0 |
| 1 | g48.t10 | Pfam | PF00067 | Cytochrome P450 | 2 | 285 | 0 |
| 7 | g48.t10 | SUPERFAMILY | SSF48264 | Cytochrome P450 | 2 | 285 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0020037 | heme binding | MF |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | MF |
| GO:0005506 | iron ion binding | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
