General information for g4841.t22
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Serine–tRNA ligase, cytoplasmic.
Parent gene
- The parent gene g4841 is located on chr_2: 5203985..5205147 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4841 | g4841.t22 | TSS | g4841.t22 | 5203197 | 5203197 |
| chr_2 | g4841 | g4841.t22 | isoform | g4841.t22 | 5203286 | 5204882 |
| chr_2 | g4841 | g4841.t22 | exon | g4841.t22.exon1 | 5203286 | 5203403 |
| chr_2 | g4841 | g4841.t22 | exon | g4841.t22.exon2 | 5203466 | 5203860 |
| chr_2 | g4841 | g4841.t22 | exon | g4841.t22.exon3 | 5203917 | 5204697 |
| chr_2 | g4841 | g4841.t22 | cds | g4841.t22.CDS1 | 5204362 | 5204697 |
| chr_2 | g4841 | g4841.t22 | exon | g4841.t22.exon4 | 5204757 | 5204882 |
| chr_2 | g4841 | g4841.t22 | cds | g4841.t22.CDS2 | 5204757 | 5204882 |
| chr_2 | g4841 | g4841.t22 | TTS | g4841.t22 | 5205040 | 5205040 |
Sequences
>g4841.t22 Gene=g4841 Length=1420
ATGGTTTTGGATATTGAGTTCTTCCGTGGTGATAAGGGAAATGACGTGAATAAAGTCCGA
ACTAATCAGGAAAAGAGATTTAAAGATCTGAAGTTAGTAGAAACAGTGATTGAACAAGAT
GCGGAATGGAGACAACGAAGATTTAAAGGCGATCTCTTCAATAAATTGAAAAATTTATGT
AGCAAAGAAATTGGAGAACGTATGAAAAAGAAAGAAGCCGCTGGTAATGAAGATGATCCA
GTTTCAGACGAATTAGTAGCAAAACTTGAAGAACTCAAGATTGATGACTTAAAACCCTTA
ACAATCGCTCAAATTAAAAAAGTACGTACTTTTATCGATGAAGCAATTGTCGAAAATGAG
AAGAAAATACTCGAGACTGAGTCGACTCGAAATAATGCTTTAAGAGAAGTCGGTAATTGG
CTCCACGAGTCTGTTCCTGTTAGCAATGACGAAGATGAGAACGGAATTGAAAGAACATGG
GGTGATTGTGAAATAAAGAAGAAATATTCTCATTGGAAATCGTGGATATTTTTTAACCGG
AGCAGCCGTTTTTCTCGAGCAAGCACTTATTCAGCATGCACTTCATATTCTTTTCAACAA
AGGCTATACACCACTTTACACTCCATTCTTTATGCGAAAGGATGTTATGCAGGAAGTAGC
ACAATTGTCTCAATTTGATGAAGAATTATACAAGGTTGTTGGAAAAAATCAAGACAAAGC
TGATGAAAATGATGAGAAATATTTAATTGCAACTTCAGAACAGCCAATTGCAGCTTATCA
TCGTGATGAATGGATTCCAGAAGCTTCATTGCCCATAAAATATGCTGGCTTATCAACTTG
TTTTCGTCAAGAAGTTGGAAGTCACGGTCGCGATACACGTGGCATCTTTCGTGTACATCA
GTTTGAAAAGATTGAACAATTTGTGCTGACATCACCTCACGACAACAAATCATGGGAAAT
GATGGATGAAATGATTGGAAACGCTGAGGAGTTTTGTCAATCATTAGGAATTCCTTATCG
CATTGTCAACATTGTTTCAGGCGCACTTAATCATGCAGCGTCAAAGAAACTTGATTTAGA
AGCTTGGTTCTGTGGATCAGGCGCTTTTAGAGAACTCGTTTCATGCAGCAATTGTCTCGA
TTATCAAGCTCGTCGTCTTCTCGTTCGTTATGGAATGACAAAGAAGATGAATGCAAATAT
TGATTATGTGCATATGCTAAATGCAACTATGTGTGCAACTACAAGAGTTATTTGCGCAAT
TCTTGAAACTCATCAAACTGAGACTGGTATTAAGGTTCCAGAAGTATTGCAGAAATACAT
GCCTGAAAAATATAAACTTGAAATTCCATTTGTTAAACCAGCTCCAATTGAAGAAGAAGA
AAAGAAAAAGGCAAAGAAGGGCAAAAAAGAAGCAGCATAA
>g4841.t22 Gene=g4841 Length=153
MMDEMIGNAEEFCQSLGIPYRIVNIVSGALNHAASKKLDLEAWFCGSGAFRELVSCSNCL
DYQARRLLVRYGMTKKMNANIDYVHMLNATMCATTRVICAILETHQTETGIKVPEVLQKY
MPEKYKLEIPFVKPAPIEEEEKKKAKKGKKEAA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g4841.t22 | Gene3D | G3DSA:3.30.930.10 | Bira Bifunctional Protein; Domain 2 | 1 | 137 | 0 |
| 2 | g4841.t22 | PANTHER | PTHR11778 | SERYL-TRNA SYNTHETASE | 1 | 132 | 0 |
| 3 | g4841.t22 | PANTHER | PTHR11778:SF7 | SERINE–TRNA LIGASE, CYTOPLASMIC-RELATED | 1 | 132 | 0 |
| 5 | g4841.t22 | PRINTS | PR00981 | Seryl-tRNA synthetase signature | 19 | 32 | 0 |
| 4 | g4841.t22 | PRINTS | PR00981 | Seryl-tRNA synthetase signature | 36 | 52 | 0 |
| 6 | g4841.t22 | PRINTS | PR00981 | Seryl-tRNA synthetase signature | 54 | 70 | 0 |
| 1 | g4841.t22 | Pfam | PF00587 | tRNA synthetase class II core domain (G, H, P, S and T) | 2 | 104 | 0 |
| 7 | g4841.t22 | SUPERFAMILY | SSF55681 | Class II aaRS and biotin synthetases | 2 | 122 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004828 | serine-tRNA ligase activity | MF |
| GO:0006418 | tRNA aminoacylation for protein translation | BP |
| GO:0000166 | nucleotide binding | MF |
| GO:0004812 | aminoacyl-tRNA ligase activity | MF |
| GO:0006434 | seryl-tRNA aminoacylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed