Gene loci information

Transcript annotation

  • This transcript has been annotated as Voltage-dependent anion-selective channel.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g4858 g4858.t80 TSS g4858.t80 5440498 5440498
chr_2 g4858 g4858.t80 isoform g4858.t80 5440540 5443261
chr_2 g4858 g4858.t80 exon g4858.t80.exon1 5440540 5440590
chr_2 g4858 g4858.t80 exon g4858.t80.exon2 5441973 5442293
chr_2 g4858 g4858.t80 cds g4858.t80.CDS1 5441974 5442293
chr_2 g4858 g4858.t80 exon g4858.t80.exon3 5442533 5442760
chr_2 g4858 g4858.t80 cds g4858.t80.CDS2 5442533 5442760
chr_2 g4858 g4858.t80 exon g4858.t80.exon4 5442906 5443106
chr_2 g4858 g4858.t80 cds g4858.t80.CDS3 5442906 5442912
chr_2 g4858 g4858.t80 exon g4858.t80.exon5 5443167 5443261
chr_2 g4858 g4858.t80 TTS g4858.t80 5443364 5443364

Sequences

>g4858.t80 Gene=g4858 Length=896
ATATCGTTTCCGTAATTCGCTCAGTCAGTAATTAATTAAAACTAATCCAAAAATGTCTCC
ACCAGCATATTCAGATTTGGGCAAAAACGCTCGCGATGTTTTCGGCAAGGGTTACCACTT
TGGTTTGTGGAAATTGGATGTTAAGACAAGAACAAACAGTGGCGTTGAATTCACCAGTGC
AGGACATTCAAATCAAGATACTGGAAAAGTTTTTGGTTCATTGGAGACCAAATACAAGTT
GAAGGAATACGGACTTACTTTCTCAGAAAAGTGGAACACAGATAACACTTTAACATCAGA
AGTTTCCGTTGAAGACCAACTCGTTAAGGGTCTCAAATTGAGTTTTGATGGCTCATTTGC
ACCACAAACAGGAAGCAAAACAGGGCGCTTCAAGACTGCATACTCGCATGAGCGTGTTCG
ATTGGATGGCGATTTCAACCTCGATTTGGGTGGTCCAATTCTTAACGCTTCAGCTGTCGT
AGACTATCAAGGATGGCTCGCTGGCTATCAATTGGCATTTGACACACAAAAGAACAAGCT
TACTGGCAACAACTTTGCACTCGGCTACAGAACTGGCGATTTCGTTTTGCATACAAATGT
GTCGTGAATTTGGAGGAAGCATTTATCAACGCTGCAGCGATCGCCTCGAAACTGGTGTAC
AATTGTCATGGGCATCAGGATCGAACGCAACTAAGTTCGGTATTGCAGCCAAGTACGATT
TGGATCGAGAGACATCTGTTCGCGCTAAAGTAAATAATGCTAGTCAAATTGGCTTGGCAT
TCCAACAAAGATTGCGCGAAGGTATCGTATTGTCATTGTCAACATTAATCGATGGCAAGA
ATTTCAATGCTGGTGGACACAAAATTGGTGTTGCTCTTGAACTCGAAGCTTTTTAA

>g4858.t80 Gene=g4858 Length=184
MSPPAYSDLGKNARDVFGKGYHFGLWKLDVKTRTNSGVEFTSAGHSNQDTGKVFGSLETK
YKLKEYGLTFSEKWNTDNTLTSEVSVEDQLVKGLKLSFDGSFAPQTGSKTGRFKTAYSHE
RVRLDGDFNLDLGGPILNASAVVDYQGWLAGYQLAFDTQKNKLTGNNFALGYRTGDFVLH
TNVS

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g4858.t80 CDD cd07306 Porin3_VDAC 3 183 0
7 g4858.t80 Gene3D G3DSA:2.40.160.10 Porin 1 184 0
2 g4858.t80 PANTHER PTHR11743:SF12 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL PROTEIN 2 3 183 0
3 g4858.t80 PANTHER PTHR11743 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL 3 183 0
5 g4858.t80 PRINTS PR00185 Eukaryotic porin signature 4 19 0
4 g4858.t80 PRINTS PR00185 Eukaryotic porin signature 67 82 0
6 g4858.t80 PRINTS PR00185 Eukaryotic porin signature 146 157 0
1 g4858.t80 Pfam PF01459 Eukaryotic porin 3 183 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0055085 transmembrane transport BP
GO:0008308 voltage-gated anion channel activity MF
GO:0005741 mitochondrial outer membrane CC
GO:0098656 anion transmembrane transport BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed