General information for g4885.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Pleckstrin homology domain-containing family G member 5.
Parent gene
- The parent gene g4885 is located on chr_2: 5783974..5796114 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g4885 | g4885.t1 | isoform | g4885.t1 | 5783974 | 5796114 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon1 | 5783974 | 5785119 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS1 | 5783974 | 5785119 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon2 | 5786645 | 5786722 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS2 | 5786645 | 5786722 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon3 | 5787677 | 5787988 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS3 | 5787677 | 5787988 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon4 | 5789229 | 5789329 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS4 | 5789229 | 5789329 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon5 | 5789555 | 5789646 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS5 | 5789555 | 5789646 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon6 | 5789720 | 5789991 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS6 | 5789720 | 5789991 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon7 | 5790056 | 5790310 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS7 | 5790056 | 5790310 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon8 | 5791654 | 5791788 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS8 | 5791654 | 5791788 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon9 | 5792049 | 5792254 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS9 | 5792049 | 5792254 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon10 | 5792436 | 5792556 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS10 | 5792436 | 5792556 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon11 | 5793845 | 5793955 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS11 | 5793845 | 5793955 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon12 | 5794025 | 5794171 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS12 | 5794025 | 5794171 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon13 | 5794256 | 5794336 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS13 | 5794256 | 5794336 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon14 | 5794462 | 5794774 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS14 | 5794462 | 5794774 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon15 | 5795030 | 5795399 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS15 | 5795030 | 5795399 |
| chr_2 | g4885 | g4885.t1 | exon | g4885.t1.exon16 | 5795781 | 5796114 |
| chr_2 | g4885 | g4885.t1 | cds | g4885.t1.CDS16 | 5795781 | 5796114 |
| chr_2 | g4885 | g4885.t1 | TSS | g4885.t1 | NA | NA |
| chr_2 | g4885 | g4885.t1 | TTS | g4885.t1 | NA | NA |
Sequences
>g4885.t1 Gene=g4885 Length=4074
ATGAGCGATAAAAACTTGCAACAGCGCAATGAAAAAAAGCATCGTAAACTTGTGAGAAGT
CCTGAGAAGCTATCGCCATGTGATTTCGATCCATTTCAAAATCCACTTCTTTTGTCGGCC
TCTTCGAATGTCTTTATCGCAACAGCAAACAACAATGTTCAACAAAATTCTTCACCAACC
AAGAGTCAACAACAAAATCTTCGTTCATCGCCTACAAAGTGCTGCTATAATGATCAGTTT
CCACCACAACAACAGCAGCAACAGCAATTATGGCGAAATAGCTATGAATCATCACCACAA
CATCAGCATCATTCAAATACAACCCTTCCACCATCATCTTCATCCCCATCGATAGCACGT
AAACCGAGCATTACGATAAAATACAGCAAAGACGATGATTTGCATCACGAGTCATCGACA
CCATCATCGCTTGCGCGTCGCCAACAAATTTCAAAGTCAATTGACTCGAATCATCCTTTT
ATTGCGACCTCCAACTCCTACACAATATCAAACGAAATGAAGGACCAAATGAGCAATAAT
TTTCTTATCAATTTTCCCAGTTTATACAATCCAAACTCATCGCATTACTTGTCATCATCT
AATAATCAGCAACAGAATACAATTGAGAAGAATTTATCGCCATTCAATTATAACAATGAT
GAATTTACTAGTGGCATAAATGTTTATAATAATGTGACATCAACAACATCTTGTGACATT
TATCATCAATCATTATCATCCGCGCATAACTCACAATCATCACTTAACCTCAATCTAGTT
AATCAACAGCAGTTTTCACAATATACTGATGGATCAATGGTAGTAACTGGAATTCCAACA
GTACCAGTATTTAACAGCAATAATCCATTTCTAAATGACAATTTTGATGCAATTCCAAAT
GATCTTGAGGGAAAATTAAATAATTTCTTCAATATTGATCAAGATGAGCTTCTTTTTATG
CCAGAAGATGAAATAACAACTACAACAAATACAACCACATTGTCAACGGCAATGATGAAG
GAAAATCATCGTGAAGATTCACAAGAGGAAGCGCAGCTGCTAAAGAATAAGCGAGAAAAA
TTTTCAAATGCTTCGACAATGAAAATTTGCTTGGTCGTCTCACCGCCCACAAATAAAGTG
TTTCATCTTAAATCAAAAAGCTTAACTCATCTGGATCGCATTCAACCGCAAATAAATATT
TCATCAAACGATAGCAATGAAAAGAATATTAATGGCGACCACGAAAATGGAATGTCTACA
ACTACCGTTAATGCGCAGACTACAAGTCAAAATGCAAAATTTACGACCGCATTAAATTGC
CTACAGAACGATTTGAGTAACAGCAATTGTATTGTAAGTGATGCAACAGTATCACATCAT
AATAGTACAATTACTTCGAATCTTACGACCATTAATTCAACAACGCATAATGATAGTCCA
ATCAAAACATCATCATCATCGACAAATATCAAAAAGAAATCGTCTTCATTCTTACATCGT
GACTACAATCGCAAGCCGATTCTTGCGAGGAGTCAAGTGTCAAGTTCAGAGTATTTTTCC
GTATGTTTTGATACAGAGAATGGATTCAAAGATAAGGATGAAATATTTATAGCGGCAACT
AAAGGCATAGCTCTCGGAGACTCACTGCGTCAGGCGATGCTTCAGAGAAGTCTAAGCTTC
TCACGAATAAGTGTGATAGATTATGGCATGAATAATTCAAATGAATTAGGCATACCACAA
TATTTTGGTCCATTGCATCTGAATACCGACATCAGTATCTTAGCCGGCCATTCACTGCTT
GTGACAGAAAAAGAAAATGTACAAAAAAAGTCTGGTCACTATGTGCTGAAGAAAGCAAAT
TCTGTTGGGTATCGAACAACAACAAGACTTTTTAGCTCGGCATCGACAGAAGAATCAACA
GGATTGGAAACAAATGATACCACAAAAGTCACAAAACAAACCAAACAACGACTTTGGTCA
CTTCAACTTTTTGGTCTTAAAAACCCACAACAAAATCAACTTTGTGAGCTACTCAATACA
TTCACAAAAAATGGCGTGCCGAAATCAAAGTCTTCCTACATCAATACAGAATACTCTGAA
GAGGCGTTGGATGCACTATATGATTTGCCATCATCATGGCATAATTTTGTCAATGCATGT
GATATTAGTGAAACCGATACGAAAATTCAATCCGCCATTTGGGAGCTCGTGACAACTGAA
GTCGATTATATTCATGCAATTCAAACTGTCACTGATTTATTTCTATCGTGCTTGGAAGGA
ATTCAATCTGAAAATCTGCTTAAGGATATCGATCAGAATAAGCTTTTCTCCAACATTCGT
GATATTGTCGATGCGAATCTGAAACTGTGGTCGCTTTATTTGTATCCAATGGTCAAACAT
AGTTTGCTTACCGGACACTTAATGTGCATCGATTATTTTCAACAAGGCTTCACCAACTTT
GCCTGCATATTTGAACCATATACAAAGTATTGTGCTGAACAAGTGCTGTGTCAGAATTAT
TGTAAGGAACTTAATCGCAACAATGCGCTATTTACCTCATATTTAGCATGGTGTGAATCG
CAGAAAGAATGTAATAGACTTCGACTTGCTGATATCCTTGTCCGCCCGATGCAACGACTG
ACCAAATATAATTTACTTTTGTCTGCCATACGAAAGCATTTAACGGAAGAGACTGAAGCG
GAAATAATGGATAACATGATTCATTCAGTGGATGAGTTTGTTTGTAGTGTCAATTCACAT
TTGACAACGAGGCAAGAAAATGAGCGACTTAAAGGAATCATGGCCCGAATTGAAAGTTAT
GATGTTGTGGATTCAAATAACGAAGGCCTAGAGAAATTGATAAAGCAATATAGTCAAATG
TTTGACTTGTGCTCACCAATGAAGGCTTGTATCGTGAATCAAGGTCGTTATTTATTCCTC
GAGGGTGATATGAAGTACAAAGATAATGTTACTAAGATGGATGTGCACTGTTTTCTATTG
ACCGATATGCTACTAATTTGTAAACAAACAGCAAAAAAGGGTCATGGTAACTTGAAGGTT
ATACGCCAACCATTTATGACCGATAGATTGGTTATTAAACTTAGGGAGAAAGAGAATGCA
CTGCATTGTGTGTACCTGAATGATTTTAACATGGTCATTGCTGCTTTCATTTTGCAATGC
AATGAAGCAAAAAATTGGTATGATGGTATCACAAAGGCACGTCACATCTATATCAAGTTG
AAGCAGGGCACATTTGTTGACGCACAAGGACACTCGGTGAAAATTCCACAACAGCAGCAT
ATGCTCTTAAACAATTATAGCATTACGGATAGTATTAGCATCAGAAAATCCCCTGTAGGA
AGTTCAATAGTTTCATCGTTAAATAACAGTCATAGTGGATCTGTCGAGCTCAATGAGTCA
AAGACCGTTTCAGTGGACTTTGATAAAACAAACTCAATATCAAGCGATGAGGGCTCGTAC
AATCTTCATAAAGCACACTCATCAGCAAGCAATAGAAAACTAAGGCAGACATCATCAAAT
TCGCTGACTGTGCAAGCATTCAACACGCATCTAAATCAATCCATGCCCAATCTTACAAGT
GGTCCTTATCATATAAACTCACACAATACATTACTTGTGCCAGGCGCTACAAAAAGTCAT
TCCGCACACTCTAGTCACTCGGGTAATTTGTTATCACCGAGTCAACGAGGAATTTCATAT
CCGCCACCAAGCCCGACTCGAGCAACCCTTAGACGTGGATTTGCATTTTCTTCATCAATT
AACAACAAAAATCCACCACTTATCAAATCTCGCAATGTTACATCACAGCATAGTTTCAAT
TTAACGCAACAGCAAAGTACACCAGCAGCTTCAGCAACCCAATTACAACAGCAGCAACAA
CAAATGCTTTCAATGGCAGCTGGAACTGCATCGTCATCAACATTGCAAGCACAATCGAGT
CAAATTCAAGTCGTATACGAACCAGTTGAACAATCAAATACAAAATCTCCAGTAGCAACT
ACTGCAGATGCATCAAATCGATTAGAAACTGATACAACGAGAAACGAAACATAA
>g4885.t1 Gene=g4885 Length=1357
MSDKNLQQRNEKKHRKLVRSPEKLSPCDFDPFQNPLLLSASSNVFIATANNNVQQNSSPT
KSQQQNLRSSPTKCCYNDQFPPQQQQQQQLWRNSYESSPQHQHHSNTTLPPSSSSPSIAR
KPSITIKYSKDDDLHHESSTPSSLARRQQISKSIDSNHPFIATSNSYTISNEMKDQMSNN
FLINFPSLYNPNSSHYLSSSNNQQQNTIEKNLSPFNYNNDEFTSGINVYNNVTSTTSCDI
YHQSLSSAHNSQSSLNLNLVNQQQFSQYTDGSMVVTGIPTVPVFNSNNPFLNDNFDAIPN
DLEGKLNNFFNIDQDELLFMPEDEITTTTNTTTLSTAMMKENHREDSQEEAQLLKNKREK
FSNASTMKICLVVSPPTNKVFHLKSKSLTHLDRIQPQINISSNDSNEKNINGDHENGMST
TTVNAQTTSQNAKFTTALNCLQNDLSNSNCIVSDATVSHHNSTITSNLTTINSTTHNDSP
IKTSSSSTNIKKKSSSFLHRDYNRKPILARSQVSSSEYFSVCFDTENGFKDKDEIFIAAT
KGIALGDSLRQAMLQRSLSFSRISVIDYGMNNSNELGIPQYFGPLHLNTDISILAGHSLL
VTEKENVQKKSGHYVLKKANSVGYRTTTRLFSSASTEESTGLETNDTTKVTKQTKQRLWS
LQLFGLKNPQQNQLCELLNTFTKNGVPKSKSSYINTEYSEEALDALYDLPSSWHNFVNAC
DISETDTKIQSAIWELVTTEVDYIHAIQTVTDLFLSCLEGIQSENLLKDIDQNKLFSNIR
DIVDANLKLWSLYLYPMVKHSLLTGHLMCIDYFQQGFTNFACIFEPYTKYCAEQVLCQNY
CKELNRNNALFTSYLAWCESQKECNRLRLADILVRPMQRLTKYNLLLSAIRKHLTEETEA
EIMDNMIHSVDEFVCSVNSHLTTRQENERLKGIMARIESYDVVDSNNEGLEKLIKQYSQM
FDLCSPMKACIVNQGRYLFLEGDMKYKDNVTKMDVHCFLLTDMLLICKQTAKKGHGNLKV
IRQPFMTDRLVIKLREKENALHCVYLNDFNMVIAAFILQCNEAKNWYDGITKARHIYIKL
KQGTFVDAQGHSVKIPQQQHMLLNNYSITDSISIRKSPVGSSIVSSLNNSHSGSVELNES
KTVSVDFDKTNSISSDEGSYNLHKAHSSASNRKLRQTSSNSLTVQAFNTHLNQSMPNLTS
GPYHINSHNTLLVPGATKSHSAHSSHSGNLLSPSQRGISYPPPSPTRATLRRGFAFSSSI
NNKNPPLIKSRNVTSQHSFNLTQQQSTPAASATQLQQQQQQMLSMAAGTASSSTLQAQSS
QIQVVYEPVEQSNTKSPVATTADASNRLETDTTRNET
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g4885.t1 | CDD | cd00160 | RhoGEF | 730 | 918 | 9.28087E-25 |
| 10 | g4885.t1 | CDD | cd13244 | PH_PLEKHG5_G6 | 976 | 1072 | 5.12487E-39 |
| 8 | g4885.t1 | Coils | Coil | Coil | 340 | 364 | - |
| 7 | g4885.t1 | Gene3D | G3DSA:1.20.900.10 | - | 709 | 938 | 6.1E-48 |
| 6 | g4885.t1 | Gene3D | G3DSA:2.30.29.30 | - | 939 | 1082 | 8.6E-9 |
| 19 | g4885.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 26 | - |
| 23 | g4885.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 23 | - |
| 13 | g4885.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 81 | 122 | - |
| 16 | g4885.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 81 | 157 | - |
| 18 | g4885.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 125 | 140 | - |
| 12 | g4885.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 141 | 157 | - |
| 21 | g4885.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1158 | 1179 | - |
| 15 | g4885.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1216 | 1237 | - |
| 20 | g4885.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1216 | 1245 | - |
| 17 | g4885.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1277 | 1296 | - |
| 14 | g4885.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1328 | 1348 | - |
| 22 | g4885.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1328 | 1357 | - |
| 2 | g4885.t1 | PANTHER | PTHR13217:SF11 | PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 5 | 473 | 1352 | 4.9E-205 |
| 3 | g4885.t1 | PANTHER | PTHR13217 | PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 | 473 | 1352 | 4.9E-205 |
| 1 | g4885.t1 | Pfam | PF00621 | RhoGEF domain | 733 | 918 | 4.7E-30 |
| 24 | g4885.t1 | ProSiteProfiles | PS50010 | Dbl homology (DH) domain profile. | 728 | 920 | 25.568 |
| 11 | g4885.t1 | SMART | SM00325 | RhoGEF_3 | 732 | 919 | 2.0E-21 |
| 5 | g4885.t1 | SUPERFAMILY | SSF48065 | DBL homology domain (DH-domain) | 709 | 940 | 6.02E-44 |
| 4 | g4885.t1 | SUPERFAMILY | SSF50729 | PH domain-like | 960 | 1075 | 4.06E-14 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K19464 (pleckstrin homology domain-containing family G member 5)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
