General information for g5573.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Proteasome subunit alpha type-5.
Parent gene
- The parent gene g5573 is located on chr_2: 10348952..10349687 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g5573 | g5573.t8 | TTS | g5573.t8 | 10347276 | 10347276 |
| chr_2 | g5573 | g5573.t8 | isoform | g5573.t8 | 10347358 | 10348313 |
| chr_2 | g5573 | g5573.t8 | exon | g5573.t8.exon1 | 10347358 | 10347962 |
| chr_2 | g5573 | g5573.t8 | cds | g5573.t8.CDS1 | 10347358 | 10347962 |
| chr_2 | g5573 | g5573.t8 | exon | g5573.t8.exon2 | 10348023 | 10348142 |
| chr_2 | g5573 | g5573.t8 | cds | g5573.t8.CDS2 | 10348023 | 10348142 |
| chr_2 | g5573 | g5573.t8 | exon | g5573.t8.exon3 | 10348307 | 10348313 |
| chr_2 | g5573 | g5573.t8 | cds | g5573.t8.CDS3 | 10348307 | 10348307 |
| chr_2 | g5573 | g5573.t8 | TSS | g5573.t8 | 10348395 | 10348395 |
Sequences
>g5573.t8 Gene=g5573 Length=732
TACAAAATGTTCCTTACACGTTCAGAATATGATAGAGGTGTCAACACTTACTCACCAGAA
GGAAGATTACTACAAGTTGAATATGCTATTGAAGCCATTAAATTGGGTAGCACTGCTATC
GGTATCAATTTTATAGGTGTAGTTATGGTTGTTGAAAAGCGTATTACATCACCATTGATG
GAACCTTCTAAAGTTGAGAAAATATTTGAAGTAGATCGTCATATTGGCTGTGCTACATCT
GGATTGATGGCTGATTCAAGAACTCTTTTGGAACGCGCAAGAGTTGAAGCTCAAAATCAT
TGGTTTGTTTATAATGAACCAATGTATGTTGAGTCATGTGCTAGAGCAGTTTCAAATTTA
GCTATTCAATTTGGAGATTCATCAGATGACAGCGGTTCGGCAATGAGTCGACCTTTCGGT
GTGGCAATTTTATTTGCTGGAGTTGATAATAATGTTCCACAATTATATCATATGGATCCA
TCTGGCACTTTGTTGAGATATGATGCGAAAGCAATTGGATCGGGTAGTGAAGGAGCTCAG
CAGCATTTGCAGGAAATTTACTCAAGCTCATTAACATTGAAAGAGGCCGTCTCAAAAGCA
CTAGAAACTCTTAAGCAAGTAATGGAAGAAAAATTGAGTTCAACAAATGTAGAAGTTATG
ACAATGACTCCAAAAGATCTCTTCTACATGTATACAAAAGAAGAGGTTGAAGCTGTAATT
GCTGATTTATAA
>g5573.t8 Gene=g5573 Length=241
MFLTRSEYDRGVNTYSPEGRLLQVEYAIEAIKLGSTAIGINFIGVVMVVEKRITSPLMEP
SKVEKIFEVDRHIGCATSGLMADSRTLLERARVEAQNHWFVYNEPMYVESCARAVSNLAI
QFGDSSDDSGSAMSRPFGVAILFAGVDNNVPQLYHMDPSGTLLRYDAKAIGSGSEGAQQH
LQEIYSSSLTLKEAVSKALETLKQVMEEKLSSTNVEVMTMTPKDLFYMYTKEEVEAVIAD
L
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g5573.t8 | CDD | cd03753 | proteasome_alpha_type_5 | 8 | 220 | 2.04511E-136 |
| 6 | g5573.t8 | Gene3D | G3DSA:3.60.20.10 | Glutamine Phosphoribosylpyrophosphate | 1 | 241 | 6.7E-84 |
| 3 | g5573.t8 | PANTHER | PTHR11599:SF14 | PROTEASOME SUBUNIT ALPHA TYPE-5 | 1 | 239 | 2.8E-100 |
| 4 | g5573.t8 | PANTHER | PTHR11599 | PROTEASOME SUBUNIT ALPHA/BETA | 1 | 239 | 2.8E-100 |
| 2 | g5573.t8 | Pfam | PF10584 | Proteasome subunit A N-terminal signature | 8 | 30 | 1.7E-12 |
| 1 | g5573.t8 | Pfam | PF00227 | Proteasome subunit | 31 | 219 | 2.8E-50 |
| 8 | g5573.t8 | ProSitePatterns | PS00388 | Proteasome alpha-type subunits signature. | 8 | 30 | - |
| 10 | g5573.t8 | ProSiteProfiles | PS51475 | Proteasome alpha-type subunit profile. | 23 | 238 | 67.434 |
| 9 | g5573.t8 | SMART | SM00948 | Proteasome_A_N_2 | 8 | 30 | 1.5E-9 |
| 5 | g5573.t8 | SUPERFAMILY | SSF56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 7 | 238 | 4.48E-71 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
Data is missing for g5573/g5573.t8; file /home/yuki.yoshida/nias/analysis/reanalysis/18_revice/midgebase/iupred3/g5573.t8.fa.iupred3.txt does not exist
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0019773 | proteasome core complex, alpha-subunit complex | CC |
| GO:0051603 | proteolysis involved in cellular protein catabolic process | BP |
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | BP |
| GO:0006511 | ubiquitin-dependent protein catabolic process | BP |
| GO:0005839 | proteasome core complex | CC |
KEGG
Orthology
- This transcript has been annotated with K02729 (20S proteasome subunit alpha 5)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
