Gene loci information

Transcript annotation

  • This transcript has been annotated as Protein disulfide-isomerase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g5788 g5788.t49 TTS g5788.t49 11940782 11940782
chr_2 g5788 g5788.t49 isoform g5788.t49 11941239 11941773
chr_2 g5788 g5788.t49 exon g5788.t49.exon1 11941239 11941773
chr_2 g5788 g5788.t49 cds g5788.t49.CDS1 11941240 11941749
chr_2 g5788 g5788.t49 TSS g5788.t49 NA NA

Sequences

>g5788.t49 Gene=g5788 Length=535
AACCGTATTTTGGAATTCTTCGGTATGAAGAAAGACGAAGTTCCATCAATGAGAATCATT
CAATTGCAAGAAGATATGGCTAAATTCAAGCCAGAAAAAGCCGATTTGAGCGCTGATGCT
ATTAAAGACTTTGTTCAAAAGTTCTTGGATGGAAAATTGAAGCAACACTTGCTTAGTCAA
GAATTACCAGAAGATTGGGATAAGAATCCAGTTAAAGTTTTGGTTTCAACCAATTTCGAT
GAAGTGGCCTTCGATAAGACAAAGGATGTTCTAGTTGAATTCTATGCTCCCTGGTGCTCG
CATTGCAAGCAACTTGCTCCAATCTACGATCAATTGGCCGAGAAATTCAAGGATAATGAT
GCTATTGTTATTGCCAAGATGGATGCTACTGTAAATGAGCTAGAACATACAAAGATTCAA
TCCTTCCCAACACTCAAATTGTACAAAAAGGGTGATAACTCAGTTGTAGATTTTAATGGT
GAACGCACACTTGAAGGATTATCGAAATTCCTTGAATCAGGTGGCTTAGAAGATG

>g5788.t49 Gene=g5788 Length=170
MKKDEVPSMRIIQLQEDMAKFKPEKADLSADAIKDFVQKFLDGKLKQHLLSQELPEDWDK
NPVKVLVSTNFDEVAFDKTKDVLVEFYAPWCSHCKQLAPIYDQLAEKFKDNDAIVIAKMD
ATVNELEHTKIQSFPTLKLYKKGDNSVVDFNGERTLEGLSKFLESGGLED

Protein features from InterProScan

Transcript Database ID Name Start End E.value
11 g5788.t49 CDD cd02995 PDI_a_PDI_a’_C 62 163 0.0000000
10 g5788.t49 Gene3D G3DSA:3.40.30.10 Glutaredoxin 1 55 0.0000000
9 g5788.t49 Gene3D G3DSA:3.40.30.10 Glutaredoxin 56 167 0.0000000
2 g5788.t49 PANTHER PTHR18929:SF101 PROTEIN DISULFIDE-ISOMERASE 1 168 0.0000000
3 g5788.t49 PANTHER PTHR18929 PROTEIN DISULFIDE ISOMERASE 1 168 0.0000000
6 g5788.t49 PRINTS PR00421 Thioredoxin family signature 82 90 0.0000001
5 g5788.t49 PRINTS PR00421 Thioredoxin family signature 90 99 0.0000001
4 g5788.t49 PRINTS PR00421 Thioredoxin family signature 130 141 0.0000001
1 g5788.t49 Pfam PF00085 Thioredoxin 63 164 0.0000000
12 g5788.t49 ProSiteProfiles PS51352 Thioredoxin domain profile. 27 168 15.5730000
8 g5788.t49 SUPERFAMILY SSF52833 Thioredoxin-like 4 59 0.0000000
7 g5788.t49 SUPERFAMILY SSF52833 Thioredoxin-like 61 165 0.0000000
13 g5788.t49 TIGRFAM TIGR01126 pdi_dom: protein disulfide-isomerase domain 66 164 0.0000000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

Data is missing for g5788/g5788.t49; file /home/yuki.yoshida/nias/analysis/reanalysis/18_revice/midgebase/iupred3/g5788.t49.fa.iupred3.txt does not exist

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0003756 protein disulfide isomerase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values