General information for g6058.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as N-acetylglucosamine-6-phosphate deacetylase.
Parent gene
- The parent gene g6058 is located on chr_2: 13952234..13954090 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6058 | g6058.t1 | TTS | g6058.t1 | 13952087 | 13952087 |
| chr_2 | g6058 | g6058.t1 | isoform | g6058.t1 | 13952234 | 13954090 |
| chr_2 | g6058 | g6058.t1 | exon | g6058.t1.exon1 | 13952234 | 13952782 |
| chr_2 | g6058 | g6058.t1 | cds | g6058.t1.CDS1 | 13952234 | 13952782 |
| chr_2 | g6058 | g6058.t1 | exon | g6058.t1.exon2 | 13952886 | 13953379 |
| chr_2 | g6058 | g6058.t1 | cds | g6058.t1.CDS2 | 13952886 | 13953379 |
| chr_2 | g6058 | g6058.t1 | exon | g6058.t1.exon3 | 13953778 | 13953835 |
| chr_2 | g6058 | g6058.t1 | cds | g6058.t1.CDS3 | 13953778 | 13953835 |
| chr_2 | g6058 | g6058.t1 | exon | g6058.t1.exon4 | 13953920 | 13954090 |
| chr_2 | g6058 | g6058.t1 | cds | g6058.t1.CDS4 | 13953920 | 13954090 |
| chr_2 | g6058 | g6058.t1 | TSS | g6058.t1 | 13954460 | 13954460 |
Sequences
>g6058.t1 Gene=g6058 Length=1272
ATGTTATCGCAATCAGTTAAGCTGATTGAGCCGTCACAAAGGCTAATCAAATTCAAAAAT
TGTCGCATTTTGCGTGATCATCGAATTTTTCGCGAGGATCTATGGGTGCGAAATGGCAAA
ATAATTAATCCCGAGCGAGTGTTTTTTGATGAAAAACGGCAAGCACATTTGCAAATTGAT
TGTCATAATGCCATTATATCGCCAGGATTTATTGACTTGCAAATTAATGGCGGTTATGGT
GTAGATTTCTCATTTGATGTCAACACTGTTGAATCGGGTGTGGCAAAGGTGTCAAAGGGT
CTATTAGCTCATGGCGTTACAAGTTTTTGTCCTACTCTTGTAACATCACCCATTGAGACA
TATCATCAAGTATTACCGAAGATTAAGAGAAAAGCAGGCGGTAAACATGGCGCGACAATA
CTTGGAGTTCATGTAGAGGGACCATTTATATCAATCGAGAAGAAAGGCGCTCATCCAGAG
AATTGTATTCGTACATTCGAAAATGGCTTCGAGACATTTGAAAATGTTTATGGAGACATT
GAAAATATTAGTATTGTAACATTGGCGCCAGAAAAACCGAGAGTTCCAGAAGTAATTACA
GAACTCGCACGACGAGGTATTGTTGTATCAGTTGGCCATTCAATGGCTGACTTGATGCAT
GGTGAGACTGCTGTTAAACATGGAGCTACTTTGATAACACATCTTTTTAATGCCATGATG
CCATTTCATCATCGTGATCCTGGTTTAGTTGGTCTATTAGCATCAAATGAAATTCCAGAA
GGTAAAACAGTATATTTTGGCATAATAACTGATGGAATTCATACACATAATGCTGCATTA
AGAATTGCATATCGTACACATCCAAGTGGTTTAATAATTGTAACTGATGCAATATCTGCA
ATGGGATTAGAAGAAGGAACACATCGAATTGGACAATATACAATTGAAGTGAGAGATCAT
AAAGCTTTTATAGCAGGCACAAATACTCTTTGTGGTTCAATTGCACCAATGGATGAATGT
GTTAGAATTTTCAAAGCTGCAACAAATTGTCCACTTGAATTTGCACTTGAAGCGGCATCA
TTACATCCTGCCAAGTGCTTAGAAATCTCAGATCGTAAAGGAACTCTTAATTATGGTGCT
GATGCTGATTTTATTTTGATGGATGATAATTTGGTCATTCATTCAACATGGATTGCTGGC
GAATGTGTATTTGAATCTGAAAGCCATGCGCTGCCACCTGTAGTTAGCCAATGGTTCGAG
GATGATGATTAA
>g6058.t1 Gene=g6058 Length=423
MLSQSVKLIEPSQRLIKFKNCRILRDHRIFREDLWVRNGKIINPERVFFDEKRQAHLQID
CHNAIISPGFIDLQINGGYGVDFSFDVNTVESGVAKVSKGLLAHGVTSFCPTLVTSPIET
YHQVLPKIKRKAGGKHGATILGVHVEGPFISIEKKGAHPENCIRTFENGFETFENVYGDI
ENISIVTLAPEKPRVPEVITELARRGIVVSVGHSMADLMHGETAVKHGATLITHLFNAMM
PFHHRDPGLVGLLASNEIPEGKTVYFGIITDGIHTHNAALRIAYRTHPSGLIIVTDAISA
MGLEEGTHRIGQYTIEVRDHKAFIAGTNTLCGSIAPMDECVRIFKAATNCPLEFALEAAS
LHPAKCLEISDRKGTLNYGADADFILMDDNLVIHSTWIAGECVFESESHALPPVVSQWFE
DDD
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g6058.t1 | CDD | cd00854 | NagA | 16 | 400 | 0 |
| 6 | g6058.t1 | Gene3D | G3DSA:2.30.40.10 | Urease | 20 | 400 | 0 |
| 7 | g6058.t1 | Gene3D | G3DSA:3.20.20.140 | - | 70 | 368 | 0 |
| 2 | g6058.t1 | PANTHER | PTHR11113 | N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE | 13 | 407 | 0 |
| 3 | g6058.t1 | PANTHER | PTHR11113:SF14 | N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE | 13 | 407 | 0 |
| 9 | g6058.t1 | PIRSF | PIRSF038994 | NagA | 13 | 407 | 0 |
| 1 | g6058.t1 | Pfam | PF01979 | Amidohydrolase family | 65 | 402 | 0 |
| 5 | g6058.t1 | SUPERFAMILY | SSF51338 | Composite domain of metallo-dependent hydrolases | 17 | 407 | 0 |
| 4 | g6058.t1 | SUPERFAMILY | SSF51556 | Metallo-dependent hydrolases | 69 | 374 | 0 |
| 8 | g6058.t1 | TIGRFAM | TIGR00221 | nagA: N-acetylglucosamine-6-phosphate deacetylase | 16 | 400 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016787 | hydrolase activity | MF |
| GO:0008448 | N-acetylglucosamine-6-phosphate deacetylase activity | MF |
| GO:0006044 | N-acetylglucosamine metabolic process | BP |
| GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | MF |
KEGG
Orthology
- This transcript has been annotated with K01443 (N-acetylglucosamine-6-phosphate deacetylase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
