General information for g6062.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative TGF-beta-activated kinase 1 and MAP3K7-binding protein 1.
Parent gene
- The parent gene g6062 is located on chr_2: 13969713..13971461 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6062 | g6062.t3 | TSS | g6062.t3 | 13968127 | 13968127 |
| chr_2 | g6062 | g6062.t3 | isoform | g6062.t3 | 13968543 | 13969764 |
| chr_2 | g6062 | g6062.t3 | exon | g6062.t3.exon1 | 13968543 | 13969764 |
| chr_2 | g6062 | g6062.t3 | cds | g6062.t3.CDS1 | 13968607 | 13969713 |
| chr_2 | g6062 | g6062.t3 | TTS | g6062.t3 | NA | NA |
Sequences
>g6062.t3 Gene=g6062 Length=1222
TTTTCTTTACTCAATATGTTCGGGTTTTAAAGGATCGTCGATAAGTGACTTTGCACTTTC
AAGAATGACAGCCGATATACTTTTAGGTGGTCAATTAAATCAATCAGACAAATCTGATGA
GTACATTAAGGAATTGCTCAAACAAACATACATATCTGCTGAAAAAGGCTATAACACTTC
CATTGATAATTTGATTGCTACAAAACAACAACTTCAATTTCAAATTCTCGATTTGAACCA
ATCAATCAACGAAATTTCACAACGACATCAAGATGTGCTCAATAGACTCAACACTATAAA
TCGAGAGCTATCAATAGGTTCATCTGTGCTTATTGCATTAATTACAAACAAAAAATTATT
TATCGCAAATCTCGGCATTTGTCGTGCACTTTTAGTTAAAAATGACATGAGAAATGATGT
GCTTCGAGTGATTCAAGTTACAGTCGATCATAATTTACAAAATGAAGATGAATTTGTGCG
TTTATATAATTTAGGACTTGATGTACAATCATTACAATCATTAAGTAGCACAAGAATGAT
TGGAAATTATATGGGTAAAGGAGGATATAAAGATTCTGCACTCTTTTCACAATCGGTTGG
TGAACCTATATTAAGCACTCCTGAAATATGCGGTCCAATTTCACTTGATGAAGATGTACG
ATTTTTACTTTTACTTAGTGGCGGACTTTGTAAAGTTCTTTCACAATTATTTTCAAGTGA
TTTAACTATAGTCAATAAGGAATTAGTACAAATTGTTGTACAACAATTTAACAAGCAAAG
TACACTTGTAGGTGTGGCTCAAAGTGTTGTTAACATTTTAGCTCAACTACATCATGATCT
TTATATGAAATCAAAAGTCAGTGGAATAGAAAGTAATTTCGAATCACGTGAAGATATGAC
TTTATTAATAAGAAATTTTTCATTTCCAATGCCTAATAGCATTGAAAAAAGTTCAAAAAG
TTCAACAGCATCTTCAACAATTTCTGGAAGTCAGAATCAAATTGACACAATAACTTCATA
TTCTTCAACTAATACAAGTGTCAATTATACACCAGATAGAAAAACTAAACCATATGTGTC
TTTTAAAGAATATTTTGCCAATGTTGAACTAGCTAGAAAAGAGAATCGACTTCCAAAAGG
AATAGATTTTGATGATGAACCATTAGAATAGTTCAAATAATTTGTCAGTGTAAAAAAAAT
TTATTAATAAAAATAAAGAAAT
>g6062.t3 Gene=g6062 Length=368
MTADILLGGQLNQSDKSDEYIKELLKQTYISAEKGYNTSIDNLIATKQQLQFQILDLNQS
INEISQRHQDVLNRLNTINRELSIGSSVLIALITNKKLFIANLGICRALLVKNDMRNDVL
RVIQVTVDHNLQNEDEFVRLYNLGLDVQSLQSLSSTRMIGNYMGKGGYKDSALFSQSVGE
PILSTPEICGPISLDEDVRFLLLLSGGLCKVLSQLFSSDLTIVNKELVQIVVQQFNKQST
LVGVAQSVVNILAQLHHDLYMKSKVSGIESNFESREDMTLLIRNFSFPMPNSIEKSSKSS
TASSTISGSQNQIDTITSYSSTNTSVNYTPDRKTKPYVSFKEYFANVELARKENRLPKGI
DFDDEPLE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g6062.t3 | CDD | cd00143 | PP2Cc | 19 | 258 | 1.77846E-24 |
| 6 | g6062.t3 | Coils | Coil | Coil | 47 | 81 | - |
| 5 | g6062.t3 | Gene3D | G3DSA:3.60.40.10 | Phosphatase 2c; Domain 1 | 2 | 288 | 3.3E-58 |
| 2 | g6062.t3 | PANTHER | PTHR13832:SF780 | TGF-BETA-ACTIVATED KINASE 1 AND MAP3K7-BINDING PROTEIN 1-LIKE PROTEIN | 1 | 318 | 8.7E-71 |
| 3 | g6062.t3 | PANTHER | PTHR13832 | PROTEIN PHOSPHATASE 2C | 1 | 318 | 8.7E-71 |
| 1 | g6062.t3 | Pfam | PF00481 | Protein phosphatase 2C | 12 | 248 | 1.1E-21 |
| 9 | g6062.t3 | ProSiteProfiles | PS51746 | PPM-type phosphatase domain profile. | 1 | 285 | 16.25 |
| 8 | g6062.t3 | SMART | SM00332 | PP2C_4 | 15 | 283 | 1.7E-4 |
| 4 | g6062.t3 | SUPERFAMILY | SSF81606 | PP2C-like | 39 | 282 | 1.57E-21 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006470 | protein dephosphorylation | BP |
| GO:0016791 | phosphatase activity | MF |
| GO:0004722 | protein serine/threonine phosphatase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
