General information for g6064.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Serine/threonine-protein phosphatase 2A activator.
Parent gene
- The parent gene g6064 is located on chr_2: 13972155..13972894 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6064 | g6064.t1 | TSS | g6064.t1 | 13971655 | 13971655 |
| chr_2 | g6064 | g6064.t1 | isoform | g6064.t1 | 13971735 | 13972821 |
| chr_2 | g6064 | g6064.t1 | exon | g6064.t1.exon1 | 13971735 | 13972027 |
| chr_2 | g6064 | g6064.t1 | cds | g6064.t1.CDS1 | 13971735 | 13972027 |
| chr_2 | g6064 | g6064.t1 | exon | g6064.t1.exon2 | 13972095 | 13972821 |
| chr_2 | g6064 | g6064.t1 | cds | g6064.t1.CDS2 | 13972095 | 13972821 |
| chr_2 | g6064 | g6064.t1 | TTS | g6064.t1 | 13972862 | 13972862 |
Sequences
>g6064.t1 Gene=g6064 Length=1020
ATGGCAGAAAATAAAGTCATAACACAAGAGCAATCAGCAATGCAGCCACCTCAACCACCG
AAAGCAAAATTCTCATTTGTTGAACCACAAAAAATGATTAAAAGTCCTATGGATATGACA
AATTGGGAAAAAAGTGAAGCGTATTATGATTTAATTGGATTTATTAGCTCTGTATGCATG
TGCATTCAAGGAAAAAGTTTACAACAGAAATGCAACATCTCACCACCTGTTCAAAAACTT
CTTGATATGCTTAATAAATTAGAAAAATTAGCAATCGAAACACCTCCAGTTGATCAACCA
AGTCGATTTGGCAATATTGCTTTTAGAACATGGTATCAAAAAATGAAAGATAATGTAGAA
TCACTTGTTAAAGATGTCTTGCCTGATGATTCCAAAGAAGCCGTTAAAGAATTGATTCCT
TATATTTTAGATTCATTTGGAAATTCTACAAGAATTGATTATGGAACTGGACATGAACTT
TCTTTCATCTTCTTTCTTATGGCACTTTTCAAAATTGGTGTTTTAGAGAAATCAGATGAA
TTGGCAGTAGCTATCAAAGTCTTTGATTTATATTTGAATTTTGTACGAAAATTACAAGTA
ACTTATAGATTAGAACCAGCTGGATCACAAGGTGTTTGGTCTTTAGACGACTTTCAATTT
CTACCGTTTATTTGGGGAAGTGCTCAACTCATCGGGACTTCAATTGAACCAGTAAAATTC
GTTGAACCTGAAACAATTGAAGAATATAGAAAAGAGTACATGTTTATATCATGCATTGAC
TACATTCAGCAAGTAAAGACAGGACATATTGCTGAGCATTCGAATCAATTATGGAGTATT
AGTGCAGTTCCATCATGGAGCAAAATTTGCACAGGTCTCATCAAAATGTATCAAAAGGAA
GTGCTTTCAAAATTTCCAGTTATTCAACATCTTCTTTTTGGTTCGATTTTCTCATTGGAT
CTAATAAAACCCGGTACAAGACTTCCACAGCCTAGACTTGGAATGGGTCCCCATAAATAA
>g6064.t1 Gene=g6064 Length=339
MAENKVITQEQSAMQPPQPPKAKFSFVEPQKMIKSPMDMTNWEKSEAYYDLIGFISSVCM
CIQGKSLQQKCNISPPVQKLLDMLNKLEKLAIETPPVDQPSRFGNIAFRTWYQKMKDNVE
SLVKDVLPDDSKEAVKELIPYILDSFGNSTRIDYGTGHELSFIFFLMALFKIGVLEKSDE
LAVAIKVFDLYLNFVRKLQVTYRLEPAGSQGVWSLDDFQFLPFIWGSAQLIGTSIEPVKF
VEPETIEEYRKEYMFISCIDYIQQVKTGHIAEHSNQLWSISAVPSWSKICTGLIKMYQKE
VLSKFPVIQHLLFGSIFSLDLIKPGTRLPQPRLGMGPHK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g6064.t1 | CDD | cd04087 | PTPA | 50 | 314 | 5.32676E-156 |
| 7 | g6064.t1 | Gene3D | G3DSA:1.20.120.1150 | - | 215 | 323 | 3.0E-44 |
| 5 | g6064.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 21 | - |
| 6 | g6064.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 18 | - |
| 2 | g6064.t1 | PANTHER | PTHR10012 | SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B | 9 | 319 | 5.1E-131 |
| 3 | g6064.t1 | PANTHER | PTHR10012:SF0 | SERINE/THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR | 9 | 319 | 5.1E-131 |
| 8 | g6064.t1 | PIRSF | PIRSF016325 | PTPA | 18 | 330 | 5.6E-128 |
| 1 | g6064.t1 | Pfam | PF03095 | Phosphotyrosyl phosphate activator (PTPA) protein | 29 | 318 | 4.2E-117 |
| 4 | g6064.t1 | SUPERFAMILY | SSF140984 | PTPA-like | 18 | 319 | 3.14E-119 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0019211 | phosphatase activator activity | MF |
KEGG
Orthology
- This transcript has been annotated with K17605 (serine/threonine-protein phosphatase 2A activator)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
