General information for g6087.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Plasma kallikrein.
Parent gene
- The parent gene g6087 is located on chr_2: 14060075..14061050 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6087 | g6087.t3 | TSS | g6087.t3 | 14059276 | 14059276 |
| chr_2 | g6087 | g6087.t3 | isoform | g6087.t3 | 14059324 | 14060386 |
| chr_2 | g6087 | g6087.t3 | exon | g6087.t3.exon1 | 14059324 | 14059369 |
| chr_2 | g6087 | g6087.t3 | cds | g6087.t3.CDS1 | 14059324 | 14059369 |
| chr_2 | g6087 | g6087.t3 | exon | g6087.t3.exon2 | 14059422 | 14059768 |
| chr_2 | g6087 | g6087.t3 | cds | g6087.t3.CDS2 | 14059422 | 14059768 |
| chr_2 | g6087 | g6087.t3 | exon | g6087.t3.exon3 | 14059829 | 14060386 |
| chr_2 | g6087 | g6087.t3 | cds | g6087.t3.CDS3 | 14059829 | 14060134 |
| chr_2 | g6087 | g6087.t3 | TTS | g6087.t3 | 14060418 | 14060418 |
Sequences
>g6087.t3 Gene=g6087 Length=951
ATGTTATGGATTACAAATTTAATACTTTTTGCATCGATTTTAAATTGTCATGGTTATGAA
AATATTGAGGGAAGAGTTGTGAATGGAGTGACAGCAAAGAATATTATACCATATCAAGCG
TCGATAAGAGTTTCTGTTAGAGATTATTTGCGCTTTGGACGAGGTCATACATGTGGAGGA
GTGTTGATATCTCGTCGAACTGTTACAACAGCTGCTCACTGTTTAACGGATGGTGCTAGA
ATGAGAACAGTCTTTGATATCCATGTTGTTTTTGGATCACTTAATCGCTACATTTTTACT
GACGAGACTGTGATAATGCATGCTGAAAAAATTATCATGCATCCCAAATATAGGAGATTT
GAAAGCTTGGAACATGACATTGGACTTGTTATTCTCAGACGAAATGTAGAGTTAAGTGAC
ATAATTCATCCGATTCCATTGATAGATTTTGCAATACCAACAGGCAATAGATGCCAAATA
AGTGGTTGGGGTGCAACACAATGGAGAGGTCTGATGCCTTTACAATTGCAAAAGGCAAAT
GTTTCAATTGTCGATAGAAATTTTTGTAATGCTTCATATTCGGAGCGTTTTGGCACTTCT
ATTACATATGGTATGGTATGTGCAAATGGTCAAACAGAATCTGGTAAAATCATTGATGCA
TGTCAAGGAGGTAAATTCAATTATGTTTTTATCATGTAGTCATTTTGTGACTTTTATTCT
TTAGATTCTGGTGGACCACTTCAGTGTGATGACAAACTTGTAGGACTTTCGTCATTTGGC
GTATCATGTGGTGCATCATTCGATATTCCTGGCGTTTATGTCGACATTTATTATTACCAC
AATTGGATTATGGAAAATTGGAAGAACAATGGTGTGATGCAAAAAAGTCACAAAACCTCA
ATTTTCATGTTCACACTTTTTGTAAATTTAATTTGGAATTTGAAGTCATAA
>g6087.t3 Gene=g6087 Length=232
MLWITNLILFASILNCHGYENIEGRVVNGVTAKNIIPYQASIRVSVRDYLRFGRGHTCGG
VLISRRTVTTAAHCLTDGARMRTVFDIHVVFGSLNRYIFTDETVIMHAEKIIMHPKYRRF
ESLEHDIGLVILRRNVELSDIIHPIPLIDFAIPTGNRCQISGWGATQWRGLMPLQLQKAN
VSIVDRNFCNASYSERFGTSITYGMVCANGQTESGKIIDACQGGKFNYVFIM
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g6087.t3 | CDD | cd00190 | Tryp_SPc | 26 | 223 | 1.06704E-45 |
| 5 | g6087.t3 | Gene3D | G3DSA:2.40.10.10 | - | 18 | 225 | 1.7E-41 |
| 2 | g6087.t3 | PANTHER | PTHR24264 | TRYPSIN-RELATED | 23 | 223 | 6.9E-36 |
| 1 | g6087.t3 | Pfam | PF00089 | Trypsin | 33 | 223 | 3.4E-33 |
| 7 | g6087.t3 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 18 | - |
| 8 | g6087.t3 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 6 | - |
| 9 | g6087.t3 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 7 | 14 | - |
| 10 | g6087.t3 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 15 | 18 | - |
| 6 | g6087.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 19 | 232 | - |
| 13 | g6087.t3 | ProSiteProfiles | PS50240 | Serine proteases, trypsin domain profile. | 26 | 232 | 20.162 |
| 12 | g6087.t3 | SMART | SM00020 | trypsin_2 | 25 | 231 | 3.8E-26 |
| 3 | g6087.t3 | SUPERFAMILY | SSF50494 | Trypsin-like serine proteases | 11 | 223 | 3.68E-48 |
| 4 | g6087.t3 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed