General information for g6087.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Plasma kallikrein.
Parent gene
- The parent gene g6087 is located on chr_2: 14060075..14061050 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6087 | g6087.t5 | TSS | g6087.t5 | 14059276 | 14059276 |
| chr_2 | g6087 | g6087.t5 | isoform | g6087.t5 | 14059422 | 14060386 |
| chr_2 | g6087 | g6087.t5 | exon | g6087.t5.exon1 | 14059422 | 14059768 |
| chr_2 | g6087 | g6087.t5 | cds | g6087.t5.CDS1 | 14059616 | 14059768 |
| chr_2 | g6087 | g6087.t5 | exon | g6087.t5.exon2 | 14059829 | 14060105 |
| chr_2 | g6087 | g6087.t5 | cds | g6087.t5.CDS2 | 14059829 | 14060105 |
| chr_2 | g6087 | g6087.t5 | exon | g6087.t5.exon3 | 14060160 | 14060386 |
| chr_2 | g6087 | g6087.t5 | cds | g6087.t5.CDS3 | 14060160 | 14060386 |
| chr_2 | g6087 | g6087.t5 | TTS | g6087.t5 | 14060418 | 14060418 |
Sequences
>g6087.t5 Gene=g6087 Length=851
GTCATGGTTATGAAAATATTGAGGGAAGAGTTGTGAATGGAGTGACAGCAAAGAATATTA
TACCATATCAAGCGTCGATAAGAGTTTCTGTTAGAGATTATTTGCGCTTTGGACGAGGTC
ATACATGTGGAGGAGTGTTGATATCTCGTCGAACTGTTACAACAGCTGCTCACTGTTTAA
CGGATGGTGCTAGAATGAGAACAGTCTTTGATATCCATGTTGTTTTTGGATCACTTAATC
GCTACATTTTTACTGACGAGACTGTGATAATGCATGCTGAAAAAATTATCATGCATCCCA
AATATAGGAGATTTGAAAGCTTGGAACATGACATTGGACTTGTTATTCTCAGACGAAATG
TAGAGTTAAGTGACATAATTCATCCGATTCCATTGATAGATTTTGCAATACCAACAGGCA
ATAGATGCCAAATAAGTGGTTGGGGTGCAACACAATGGAGAGGTCTGATGCCTTTACAAT
TGCAAAAGGCAAATGTTTCAATTGTCGATAGAAATTTTTGTAATGCTTCATATTCGGAGC
GTTTTGGCACTTCTATTACATATGGTATGGTATGTGCAAATGGTCAAACAGAATCTGGTA
AAATCATTGATGCATGTCAAGGAGATTCTGGTGGACCACTTCAGTGTGATGACAAACTTG
TAGGACTTTCGTCATTTGGCGTATCATGTGGTGCATCATTCGATATTCCTGGCGTTTATG
TCGACATTTATTATTACCACAATTGGATTATGGAAAATTGGAAGAACAATGGTGTGATGC
AAAAAAGTCACAAAACCTCAATTTTCATGTTCACACTTTTTGTAAATTTAATTTGGAATT
TGAAGTCATAA
>g6087.t5 Gene=g6087 Length=218
MRTVFDIHVVFGSLNRYIFTDETVIMHAEKIIMHPKYRRFESLEHDIGLVILRRNVELSD
IIHPIPLIDFAIPTGNRCQISGWGATQWRGLMPLQLQKANVSIVDRNFCNASYSERFGTS
ITYGMVCANGQTESGKIIDACQGDSGGPLQCDDKLVGLSSFGVSCGASFDIPGVYVDIYY
YHNWIMENWKNNGVMQKSHKTSIFMFTLFVNLIWNLKS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g6087.t5 | CDD | cd00190 | Tryp_SPc | 2 | 188 | 3.35276E-50 |
| 4 | g6087.t5 | Gene3D | G3DSA:2.40.10.10 | - | 2 | 191 | 4.7E-44 |
| 2 | g6087.t5 | PANTHER | PTHR24264 | TRYPSIN-RELATED | 6 | 190 | 2.8E-42 |
| 1 | g6087.t5 | Pfam | PF00089 | Trypsin | 7 | 185 | 1.6E-36 |
| 6 | g6087.t5 | ProSitePatterns | PS00135 | Serine proteases, trypsin family, serine active site. | 139 | 150 | - |
| 8 | g6087.t5 | ProSiteProfiles | PS50240 | Serine proteases, trypsin domain profile. | 1 | 190 | 20.321 |
| 7 | g6087.t5 | SMART | SM00020 | trypsin_2 | 2 | 185 | 8.2E-30 |
| 3 | g6087.t5 | SUPERFAMILY | SSF50494 | Trypsin-like serine proteases | 5 | 192 | 1.11E-51 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed