General information for g6124.t6
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Serine/threonine-protein kinase/endoribonuclease ire-1.
Parent gene
- The parent gene g6124 is located on chr_2: 14395494..14395869 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6124 | g6124.t6 | TTS | g6124.t6 | 14394334 | 14394334 |
| chr_2 | g6124 | g6124.t6 | isoform | g6124.t6 | 14394527 | 14395869 |
| chr_2 | g6124 | g6124.t6 | exon | g6124.t6.exon1 | 14394527 | 14394533 |
| chr_2 | g6124 | g6124.t6 | cds | g6124.t6.CDS1 | 14394527 | 14394533 |
| chr_2 | g6124 | g6124.t6 | exon | g6124.t6.exon2 | 14394603 | 14394950 |
| chr_2 | g6124 | g6124.t6 | cds | g6124.t6.CDS2 | 14394603 | 14394950 |
| chr_2 | g6124 | g6124.t6 | exon | g6124.t6.exon3 | 14395024 | 14395137 |
| chr_2 | g6124 | g6124.t6 | cds | g6124.t6.CDS3 | 14395024 | 14395137 |
| chr_2 | g6124 | g6124.t6 | exon | g6124.t6.exon4 | 14395208 | 14395459 |
| chr_2 | g6124 | g6124.t6 | cds | g6124.t6.CDS4 | 14395208 | 14395459 |
| chr_2 | g6124 | g6124.t6 | exon | g6124.t6.exon5 | 14395603 | 14395685 |
| chr_2 | g6124 | g6124.t6 | cds | g6124.t6.CDS5 | 14395603 | 14395685 |
| chr_2 | g6124 | g6124.t6 | exon | g6124.t6.exon6 | 14395795 | 14395869 |
| chr_2 | g6124 | g6124.t6 | cds | g6124.t6.CDS6 | 14395795 | 14395869 |
| chr_2 | g6124 | g6124.t6 | TSS | g6124.t6 | 14395958 | 14395958 |
Sequences
>g6124.t6 Gene=g6124 Length=879
ATGAAATTTAATTTTATAATTTTATGTACATTATTACATTTGATTGGATCAAATGGTGAA
CAGCCTAAAAAGCAGGATTGTACCGATGTACTGCGAACAGAAGAAAAGAATGAACCACTT
CTAGTGCTTTCGACGTTAAATGGAGATTTGTTAGCTATAGAACCTCAAAACGGGGAAGTG
AAATGGAAACAAGTTAATGAGCCTTCAGTTAAAACAGAAAATAATGATCAATTATCGAAC
TCTGTGTACTTTCCTGATCCTGTGAGTGGGAGTTTATATAAATTAAAAGTTCAAGATGAT
AAAAACAATGTGCTCAAAAAGTTGCCTTTCACAATACCAGAACTTGTCAATCGCTCACCA
TGCAAATCAAGTGATGGTATTTTATACTCTGGAAAAAAATCTGATAATTGGTTTATAATT
GATCCTAAAACCGGCAAACGTGAATTTATTATGGGTTTTGGGGCGAAGGCAGATTCGTCT
GATATTTTAGGATATGCAACTTCACGGTCGGTGTATCTCGGAAGAACACAATACACAGTT
TTGATGTACGACACAACTGAAACGAATAGCAAACCATGGAACATTTCTTTTTTCGATTAC
AATTCACATACTATGGCGCCCGAAATTTTAGAAAAATATGAATTCATTCATGTCACTTCT
TCTACAACTGGAAAAATTGTTACAATGAGCAAAAAGAACAATAATTTTCTATGGTCATTA
ACTGATGAAAATTATAAATCGCCAATCGTTGCAATTTTTATCCTTTCGAGTGAAGGCTTT
TTAAGTGTACCATTCACAACTGTATCAGAAAATGTTATAGAAAAAGTTCTTGATTATAGT
TTGAGTGAGACAAAAAGTGATTTCCAATTATATGAGACA
>g6124.t6 Gene=g6124 Length=293
MKFNFIILCTLLHLIGSNGEQPKKQDCTDVLRTEEKNEPLLVLSTLNGDLLAIEPQNGEV
KWKQVNEPSVKTENNDQLSNSVYFPDPVSGSLYKLKVQDDKNNVLKKLPFTIPELVNRSP
CKSSDGILYSGKKSDNWFIIDPKTGKREFIMGFGAKADSSDILGYATSRSVYLGRTQYTV
LMYDTTETNSKPWNISFFDYNSHTMAPEILEKYEFIHVTSSTTGKIVTMSKKNNNFLWSL
TDENYKSPIVAIFILSSEGFLSVPFTTVSENVIEKVLDYSLSETKSDFQLYET
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g6124.t6 | Gene3D | G3DSA:2.130.10.10 | - | 36 | 263 | 7.9E-9 |
| 1 | g6124.t6 | PANTHER | PTHR13954:SF15 | SERINE/THREONINE-PROTEIN KINASE/ENDORIBONUCLEASE IRE2 | 35 | 280 | 8.0E-52 |
| 2 | g6124.t6 | PANTHER | PTHR13954 | IRE1-RELATED | 35 | 280 | 8.0E-52 |
| 11 | g6124.t6 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 19 | - |
| 12 | g6124.t6 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 4 | - |
| 13 | g6124.t6 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 5 | 15 | - |
| 14 | g6124.t6 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 16 | 19 | - |
| 10 | g6124.t6 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 20 | 293 | - |
| 7 | g6124.t6 | SMART | SM00564 | ire1_9 | 33 | 65 | 47.0 |
| 5 | g6124.t6 | SMART | SM00564 | ire1_9 | 120 | 152 | 9.0 |
| 6 | g6124.t6 | SMART | SM00564 | ire1_9 | 164 | 196 | 62.0 |
| 4 | g6124.t6 | SMART | SM00564 | ire1_9 | 207 | 241 | 620.0 |
| 3 | g6124.t6 | SUPERFAMILY | SSF50998 | Quinoprotein alcohol dehydrogenase-like | 39 | 261 | 2.75E-9 |
| 8 | g6124.t6 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 19 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed