General information for g617.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative ETV5-related protein Ets96B.
Parent gene
- The parent gene g617 is located on chr_3: 4531142..4533851 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g617 | g617.t1 | isoform | g617.t1 | 4521862 | 4531142 |
| chr_3 | g617 | g617.t1 | exon | g617.t1.exon1 | 4521862 | 4522069 |
| chr_3 | g617 | g617.t1 | cds | g617.t1.CDS1 | 4521862 | 4522069 |
| chr_3 | g617 | g617.t1 | exon | g617.t1.exon2 | 4522145 | 4522225 |
| chr_3 | g617 | g617.t1 | cds | g617.t1.CDS2 | 4522145 | 4522225 |
| chr_3 | g617 | g617.t1 | exon | g617.t1.exon3 | 4522792 | 4522855 |
| chr_3 | g617 | g617.t1 | cds | g617.t1.CDS3 | 4522792 | 4522855 |
| chr_3 | g617 | g617.t1 | exon | g617.t1.exon4 | 4522919 | 4522983 |
| chr_3 | g617 | g617.t1 | cds | g617.t1.CDS4 | 4522919 | 4522983 |
| chr_3 | g617 | g617.t1 | exon | g617.t1.exon5 | 4530440 | 4530922 |
| chr_3 | g617 | g617.t1 | cds | g617.t1.CDS5 | 4530440 | 4530922 |
| chr_3 | g617 | g617.t1 | exon | g617.t1.exon6 | 4530979 | 4531142 |
| chr_3 | g617 | g617.t1 | cds | g617.t1.CDS6 | 4530979 | 4531142 |
| chr_3 | g617 | g617.t1 | TTS | g617.t1 | 4531186 | 4531186 |
| chr_3 | g617 | g617.t1 | TSS | g617.t1 | NA | NA |
Sequences
>g617.t1 Gene=g617 Length=1065
ATGTATGCACATTTATGTCATACCGAAGATTCACATGATATTGAAGAGAGAAGTAACTCG
AAGAGACTTTTGCAATATTATCCACAGCAATTTCATTCTAACATTACGACTGCTTCACGC
TCATCTTCACCTCCAAAAACGCCATTTACTTCATTACACTTTCCAGTTCAGCAAATTTAT
AATGGACATATGAGCAATTTAAATGATGAATATATAAGCAACGACTTTCGACTGAACAGA
GATATTTGGCCGCAGGAAACTGTTATTACTGAAGATCCAACTACATTAGGTAAAGATAAT
TTTCGAAGCGAACGTTCATCGTTTGTTGAATTTTCAAAGCAAGGATACTACAGATTGACT
AATTCTTCTTTATCACCGACATCACAATCAGCACTAGTAAAAAGAGAATTCAATGAAGTT
GGTTGGCATCATCATCCTCATTATAGTTTTCCTGAACATCAACTATATGCAACGGCAACA
CCAACAAATACTTCAATTTATCAACAACAACCTGATTCAACATCATCTCATCAAGTTGCA
AGTGAAATTGTGTATTATAATAATTCAGATTCCTCAGATTTTGTGACTACAACATCAAAT
TCAAATGTGACAACAACACCACCAGCTGCACATCAATTACAAAGCAATAGCTTAAATTCA
CCAATGAATTTTCAACAACGACGTGGATCATTACAATTGTGGCAGTTTCTCATAGCTCTT
TTAGACGATTCTAGTAGCAGCTCATGTATAACTTGGACAGGAAGAGGAATGGAATTTAAA
TTGATCGAACCTGAAGAAGTTGCAAGAAGATGGGGTATTCAAAAGAATAGACCTGCTATG
AATTATGATAAATTGAGTCGAAGTTTGCGTTATTATTATGAAAAAGGAATAATGCAAAAA
GTTGCTGGTGAAAGATACGTTTACAAATTTGTTTGCAGTCCTGAGGCTCTTTTTAATATG
GCTTATTCAAACGCTGCAAATAATACTTCCAATGGAGCAGAAAATGGACGCAATTCGGTC
GATAAAAATCAATATTTTAATCAAAATTATTCACAAACTTCTTAA
>g617.t1 Gene=g617 Length=354
MYAHLCHTEDSHDIEERSNSKRLLQYYPQQFHSNITTASRSSSPPKTPFTSLHFPVQQIY
NGHMSNLNDEYISNDFRLNRDIWPQETVITEDPTTLGKDNFRSERSSFVEFSKQGYYRLT
NSSLSPTSQSALVKREFNEVGWHHHPHYSFPEHQLYATATPTNTSIYQQQPDSTSSHQVA
SEIVYYNNSDSSDFVTTTSNSNVTTTPPAAHQLQSNSLNSPMNFQQRRGSLQLWQFLIAL
LDDSSSSSCITWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQK
VAGERYVYKFVCSPEALFNMAYSNAANNTSNGAENGRNSVDKNQYFNQNYSQTS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g617.t1 | Gene3D | G3DSA:1.10.10.10 | winged helix repressor DNA binding domain | 190 | 329 | 1.0E-49 |
| 12 | g617.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 332 | 354 | - |
| 2 | g617.t1 | PANTHER | PTHR11849:SF160 | ETS TRANSLOCATION VARIANT 5 | 205 | 324 | 2.3E-73 |
| 3 | g617.t1 | PANTHER | PTHR11849 | ETS | 205 | 324 | 2.3E-73 |
| 5 | g617.t1 | PRINTS | PR00454 | ETS domain signature | 231 | 244 | 1.6E-28 |
| 6 | g617.t1 | PRINTS | PR00454 | ETS domain signature | 255 | 273 | 1.6E-28 |
| 7 | g617.t1 | PRINTS | PR00454 | ETS domain signature | 274 | 292 | 1.6E-28 |
| 4 | g617.t1 | PRINTS | PR00454 | ETS domain signature | 293 | 311 | 1.6E-28 |
| 1 | g617.t1 | Pfam | PF00178 | Ets-domain | 232 | 311 | 7.7E-34 |
| 10 | g617.t1 | ProSitePatterns | PS00346 | Ets-domain signature 2. | 277 | 292 | - |
| 13 | g617.t1 | ProSiteProfiles | PS50061 | Ets-domain profile. | 231 | 311 | 39.977 |
| 11 | g617.t1 | SMART | SM00413 | etsneu2 | 230 | 315 | 8.2E-55 |
| 8 | g617.t1 | SUPERFAMILY | SSF46785 | Winged helix DNA-binding domain | 229 | 326 | 5.44E-46 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | BP |
| GO:0043565 | sequence-specific DNA binding | MF |
| GO:0003700 | DNA-binding transcription factor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K15593 (ets translocation variant 5)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
