General information for g619.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as histone-arginine N-methyltransferase.
Parent gene
- The parent gene g619 is located on chr_3: 4535171..4535914 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g619 | g619.t3 | TTS | g619.t3 | 4534214 | 4534214 |
| chr_3 | g619 | g619.t3 | isoform | g619.t3 | 4534564 | 4535914 |
| chr_3 | g619 | g619.t3 | exon | g619.t3.exon1 | 4534564 | 4535106 |
| chr_3 | g619 | g619.t3 | cds | g619.t3.CDS1 | 4534565 | 4535106 |
| chr_3 | g619 | g619.t3 | exon | g619.t3.exon2 | 4535166 | 4535607 |
| chr_3 | g619 | g619.t3 | cds | g619.t3.CDS2 | 4535166 | 4535607 |
| chr_3 | g619 | g619.t3 | exon | g619.t3.exon3 | 4535912 | 4535914 |
| chr_3 | g619 | g619.t3 | cds | g619.t3.CDS3 | 4535912 | 4535914 |
| chr_3 | g619 | g619.t3 | TSS | g619.t3 | 4536066 | 4536066 |
Sequences
>g619.t3 Gene=g619 Length=988
ATGAGTGACTCACAACCAATGGAAATTTCAAATGAAAATGGAACACACAATCAAAAAGAA
AAGGCATCAATCAAAAATCAATCACCTGAAGAAATGACAAGTCGCGACTATTACTTTGAT
AGTTATGCTCATTTTGGAATACATGAAGAAATGCTAAAAGACGAAGTCAGAACTATGACA
TACAGGAATGCAATGTATCACAATAAACATTTGTTCAAAGGCAAAACTGTGGTCGATGTA
GGTTGCGGCACTGGAATACTTTCAATGTTTGCAGCAAAAGCAGGAGCAGCACGAGTTTTT
GCCATCGAGTGCTCAAATATTGCAGATTATGCTACAAAAATTATTGCCGAAAATAAGCTT
GATCATATTATTACATTGGTCAAAGGCAAAGTTGAGGAAGTTGTTTTACCTGATGGCATT
GAAAAAGTCGATATTATCATCTCCGAATGGATGGGATATTGCTTGTTTTATGAATCTATG
CTTGATACGGTTCTTTTTGCTCGAGACAAATGGTTGGATAAACAAAATGGAATGATGTTT
CCTGACAAATGCACATTATATGTGACTTCGATTGAAGATCGTCAATATAAGGATGAGAAA
ATTAATTGGTGGGACGATGTTTACGGTTTTAATATGTCTCATATTCGAAAAGTTGCTATA
AGTGAACCACTTGTGGACGTAGTTGATCAGAAACAAGTTGTCACAAATTCTTATCTTGTA
AAAGAAATTGACTTGTATACCGTACAAAAAGAAGATCTTGCATTTACCAGTGACTTCCAT
TTAGTTGTTAAACGAAATGATTTTATTCAAGCATTAGTAACTTATTTCAATGTCGAGTTT
ACCAAGTGCCACAAACGACTCGGTTTCTCAACAAGTCCCGATGCTCCATATACTCACTGG
AAACAAACAGTATTTTACTTAGACGACTATATTACAGCTAAAAAGGGTGAAGAGATATTT
GGAACTTTTTCCATGCAACCAAATGAAA
>g619.t3 Gene=g619 Length=329
MSDSQPMEISNENGTHNQKEKASIKNQSPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTMT
YRNAMYHNKHLFKGKTVVDVGCGTGILSMFAAKAGAARVFAIECSNIADYATKIIAENKL
DHIITLVKGKVEEVVLPDGIEKVDIIISEWMGYCLFYESMLDTVLFARDKWLDKQNGMMF
PDKCTLYVTSIEDRQYKDEKINWWDDVYGFNMSHIRKVAISEPLVDVVDQKQVVTNSYLV
KEIDLYTVQKEDLAFTSDFHLVVKRNDFIQALVTYFNVEFTKCHKRLGFSTSPDAPYTHW
KQTVFYLDDYITAKKGEEIFGTFSMQPNE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g619.t3 | CDD | cd02440 | AdoMet_MTases | 76 | 148 | 1.90516E-11 |
| 7 | g619.t3 | Gene3D | G3DSA:3.40.50.150 | Vaccinia Virus protein VP39 | 26 | 181 | 1.6E-63 |
| 6 | g619.t3 | Gene3D | G3DSA:2.70.160.11 | - | 183 | 329 | 1.9E-58 |
| 5 | g619.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 30 | - |
| 2 | g619.t3 | PANTHER | PTHR11006 | PROTEIN ARGININE N-METHYLTRANSFERASE | 25 | 329 | 6.5E-165 |
| 3 | g619.t3 | PANTHER | PTHR11006:SF47 | PROTEIN ARGININE N-METHYLTRANSFERASE 8 | 25 | 329 | 6.5E-165 |
| 1 | g619.t3 | Pfam | PF06325 | Ribosomal protein L11 methyltransferase (PrmA) | 71 | 148 | 9.0E-10 |
| 8 | g619.t3 | ProSiteProfiles | PS51678 | SAM-dependent methyltransferase PRMT-type domain profile. | 35 | 329 | 92.829 |
| 4 | g619.t3 | SUPERFAMILY | SSF53335 | S-adenosyl-L-methionine-dependent methyltransferases | 41 | 328 | 3.22E-88 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016274 | protein-arginine N-methyltransferase activity | MF |
| GO:0018216 | peptidyl-arginine methylation | BP |
KEGG
Orthology
- This transcript has been annotated with K11434 (type I protein arginine methyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
