General information for g6191.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Hemicentin-1.
Parent gene
- The parent gene g6191 is located on chr_2: 15122666..15123342 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6191 | g6191.t1 | TTS | g6191.t1 | 15054032 | 15054032 |
| chr_2 | g6191 | g6191.t1 | isoform | g6191.t1 | 15054089 | 15123342 |
| chr_2 | g6191 | g6191.t1 | exon | g6191.t1.exon1 | 15054089 | 15054288 |
| chr_2 | g6191 | g6191.t1 | cds | g6191.t1.CDS1 | 15054089 | 15054288 |
| chr_2 | g6191 | g6191.t1 | exon | g6191.t1.exon2 | 15054361 | 15054744 |
| chr_2 | g6191 | g6191.t1 | cds | g6191.t1.CDS2 | 15054361 | 15054744 |
| chr_2 | g6191 | g6191.t1 | exon | g6191.t1.exon3 | 15057044 | 15057418 |
| chr_2 | g6191 | g6191.t1 | cds | g6191.t1.CDS3 | 15057044 | 15057418 |
| chr_2 | g6191 | g6191.t1 | exon | g6191.t1.exon4 | 15057875 | 15060028 |
| chr_2 | g6191 | g6191.t1 | cds | g6191.t1.CDS4 | 15057875 | 15060028 |
| chr_2 | g6191 | g6191.t1 | exon | g6191.t1.exon5 | 15097301 | 15097497 |
| chr_2 | g6191 | g6191.t1 | cds | g6191.t1.CDS5 | 15097301 | 15097497 |
| chr_2 | g6191 | g6191.t1 | exon | g6191.t1.exon6 | 15098247 | 15098507 |
| chr_2 | g6191 | g6191.t1 | cds | g6191.t1.CDS6 | 15098247 | 15098507 |
| chr_2 | g6191 | g6191.t1 | exon | g6191.t1.exon7 | 15098887 | 15099079 |
| chr_2 | g6191 | g6191.t1 | cds | g6191.t1.CDS7 | 15098887 | 15099079 |
| chr_2 | g6191 | g6191.t1 | exon | g6191.t1.exon8 | 15123297 | 15123342 |
| chr_2 | g6191 | g6191.t1 | cds | g6191.t1.CDS8 | 15123297 | 15123342 |
| chr_2 | g6191 | g6191.t1 | TSS | g6191.t1 | 15123974 | 15123974 |
Sequences
>g6191.t1 Gene=g6191 Length=3810
ATGGATTTACTCAAACGGATTAAATTTTTCTTTTTACTATCAATTGTGCTAATAGTGCTG
ACAAATGCAAATGGTGAAGATATTTCAATGGATACTCGAGACGGCGAAGATCTGATGCTT
CAATGTCGATTTAGTCCAGACTATTCAAGTAAAGATTTCATTTACTATTGGGCACGCAGT
TCACAACAGAAATTCGAAAATGTTGCTGTTGATCGCAATGCATTGAGTTCAACATACAAA
GTGGATTTCCGACCAGAAAAGGGTATTTATGATTTACGCATCACAAATGCATCATATAAT
CGAGATAATGGTCGATTTGAATGTCGCATCAAAGCACAAGGCACTGGTGATGATGTTCAT
CAGCAATATTACAATTTGACAGTTCTCACACCGCCACAGCCACCTCTTGTTGCACCAGGC
AATATTGTCGTTGCTACAGAAGAAAAGAAACAGGAATTGACATGCAGTAGTATTGGTGGC
TCTCCTGATCCAACTATCACATGGTATCGTGAAGGCACAAATGCGCCATTGCAGGCGATC
GTAAATCGTGGCGGTTCAAAGGATCATCAAACGACTAGCACATTGACCATTACACCCACA
AAGGATGATGATGGCGCACGCTATCGCTGTGTTGTATATAATCGTGCCATGAAGGAAGGC
GAAAAGTATGAGACGACCGTTACACTAAGTGTTAACTATTATCCACGTGTTGAAGTAGGT
CCCGAGAATCCATTACGTGTTGAACGTGATGGCACAGCAAAATTGGATTGTAATGTCGAT
GCGAAACCAAAAGTGACAAATGTTAGATGGACGAGAGGCGGACGTTTCATTAGCTCATCA
TTCTCGCATACAATTCATCGCGTGTCTGTACAGGATGCGGGCGAATATGAATGTACAGCT
GACAATGGTTTAGGACAAGTTGGTACTGCCAAAATTCAACTCGATGTACTTTTTGCACCA
GTTGTTGTTATCGAAACAAAAACACGCGAAGCTGAAGAACGCGAAAGCATTAACATTAAA
TGCAATGTCACTTCAAATCCACCACCTGTTGAGATTGAATGGGTTAAAGAAGGTAATCCT
GATTTTCGTCAATCAAGTGAAGTACTGTCAATCAATGATATTCGTGCGGAACATGCTGGC
ACTTATATTTGTCGCGGTATAAACAATATGCGTCCATATGGCGCGAAAGCAACTGAACGT
GTTGGAAATTCAACTGTCGCAGTACTTGTTCGTCATAGACCAGGAAAAGCTGTTATAACA
CCTAACAAACCAGTCGTTCATGTTGGCAATAGTGTGACTTTTACATGTTCCGCTAGCCCT
CCAGGCTGGCCAGTTCCACAATATAGATGGTTTAGAGATATTGAAGGTGAAATTTCTACA
CAAAAAGTTTTATCACAAGGATCGCAATATGTCATACCGCGTGCACATCTCGGTAGCGAA
GGCCGTTATCATTGTCATGCAGCAAATGAATTAGGACATGGAGAAATGGCAACAATAACG
CTCGAAGTGCATCAACCGCCACAATTTCTTGCTAAATTGCAGCAACATTTGACTCGACGT
GTAGGCGATAGTGATTTTAGTGTTTCATGCAGTGCAAAAGGAAAACCAAAACCAGCAGTC
AAATGGTTTAAAGATGGCCGTGAATTAACTGGTGAAGCAAATTTCTATGAAATAACAACA
TCACCAAATGAAGGTCCAAATGGAATGGTCACTGTTCAAAGCAATCTCAAATTTTTCGGT
AAAGGACGACCAAATTCAAATCAACTTTTGCCCAATGATCGTGGAACTTACTCATGCGTA
TATCAAAATGAAGTCAACTCTGCTAATTCAACAATGCATTTGAAAATTGAACATGAACCA
ATCATTCTACATCAATACAATAAAGTTGCTGCTGATTTGCGAGAAACTGCTGTTGTTGTT
TGCAAAGTTCAAGCTTATCCAAAGCCAGAATTTCAATGGACTTTTGGCACAAATACAGCT
CCAATTTCAATGAGCTCTGATGCACATTATGAAATCAACACCCAAAGTGATAACAATGAT
ATCTACACGAGTACACTTAAAATTCACAATGTTCGTCACAATGATTATGGCGAGTATAAT
TGCCGCGCTTCAAATTCACTTGAGACAATTAGAGCACCAATTAGATTACAACCTAAAGGT
GCTCCCGAGAAACCTACAAACCTTGATGCTGCCGACATTGGATCAAATTACATTTCACTC
AATTGGACGCCCGGCTTTGACGGTGGTCTTAGCAACACAAAGTTCTTTGTTCTATATCGA
AAAGTGTCAATTCCAAGTAATGAAGTGAATGGCGATTGTGGGTCATATTATACATCGTCG
CCCGACTGGTCAGAATTTGATTGTCATAGAAATTATCCCTGCAACATCACGCCCTTGGAT
CAACATTCAAGTTATGTATTTAAAGTTAAGGCAATGAACACGAAAGGCAATTCAGAATAT
TCGAGCGAGATTACGAAAACGACTAAAGTAAGCAAAATCCCATCCGCATTACGTGTCTCA
TACGATCCTTCGACGAAAATGTTGGGCATAAATGTCGGTCAGACATGCTTAGCACTTACG
GCAGTTGTAGAGACTATGTTACATGCTGAGACACATGTTCCAGAATGGCATATTGTTGGG
CAAATTCCATTACAAGCTTCAGGCAATGCACCGACATTCAAGGAATCAATTGTTGAGAAT
ATTATAATTCCAAGACGAAGTGCAGCACGCTCATTAGAGGATGAAGAAGATTTTACAATG
GCACTCGAGGATGAAAGCATGCCACGCGTAAGAGTCAAATTGTGCCTGCGAGGTAACCCA
GAACATTGTGGTGAATACATTGGAGCTGAAATCGGTCCATCATATATTCAGGACGTGGCT
TCAATTAACATGCCAACATTGGTGGCAATTGTCGTATCATGTATAGTTTTTGCTCTTTTC
ATTGGACTATTGCTTATGTTCTGTCGATGCAAAAAGAAGCAAACGAAAAAGAGTGTGCAG
GCAAAGGACTATGAAATGGATTCCGTTCGTCCATCAATTGTCGCACAACAAAATCAAGCA
CCGCCTCCTTACTATCCCGCAAGTGGTCTCGAGAACAAGGCACTCGAGCATTCAATGGAT
CTCGCTCTAGCTATGGAAGATCAAAAGACTGCAATTTATGCCACACAAAATGGATATGGT
TACAATAGCGGTTTGCAAGTGCCATCACATAACATTCCTCCTGATTGGGTCAACATGGGC
TATATGGAAAATAGTTATTCAAATTCAAACAATGGCGGAAGCGTAAATTCACAAGATTCA
CTTTATCAAATGAAAATGTCAGCAGCTGCAAGCAATTCTGGTAATTTAATTTCACAGCAT
CATCAATATGTTGAACGACAGCAGCCATCATATGGCTATGATCCTTTAACTCATGGTGGC
TATGGCACTGTAGACGACGATTATGCAACTTATCCACATTTGGCAACTACTCCATCACAA
CAAATGATAGCAGATGATTATCACAATCAAATGATGATGGCACAGCAGCCACCATCACGA
CAAGACTATTGTTCTGATCCATATGCAGCTGTACATAAACCAAATAAAAAGAGATTAGAC
TCACATATGGAATCGCCCTATCATGATGTCAGTGGCCTACCCGATCCATATATGGAACAA
CAAATGAATATGGGCGAAGATCAGCTAGATCATCCTAAGCCGCCGCAGCATTTGCCACAG
CATCTTGGTGGCTATGATGAAAACCTCGAAAGCGGCTATTCGACACCCAATTCACGAAAT
CGACGCGTTATACGCGAAATAATTGTCTGA
>g6191.t1 Gene=g6191 Length=1269
MDLLKRIKFFFLLSIVLIVLTNANGEDISMDTRDGEDLMLQCRFSPDYSSKDFIYYWARS
SQQKFENVAVDRNALSSTYKVDFRPEKGIYDLRITNASYNRDNGRFECRIKAQGTGDDVH
QQYYNLTVLTPPQPPLVAPGNIVVATEEKKQELTCSSIGGSPDPTITWYREGTNAPLQAI
VNRGGSKDHQTTSTLTITPTKDDDGARYRCVVYNRAMKEGEKYETTVTLSVNYYPRVEVG
PENPLRVERDGTAKLDCNVDAKPKVTNVRWTRGGRFISSSFSHTIHRVSVQDAGEYECTA
DNGLGQVGTAKIQLDVLFAPVVVIETKTREAEERESINIKCNVTSNPPPVEIEWVKEGNP
DFRQSSEVLSINDIRAEHAGTYICRGINNMRPYGAKATERVGNSTVAVLVRHRPGKAVIT
PNKPVVHVGNSVTFTCSASPPGWPVPQYRWFRDIEGEISTQKVLSQGSQYVIPRAHLGSE
GRYHCHAANELGHGEMATITLEVHQPPQFLAKLQQHLTRRVGDSDFSVSCSAKGKPKPAV
KWFKDGRELTGEANFYEITTSPNEGPNGMVTVQSNLKFFGKGRPNSNQLLPNDRGTYSCV
YQNEVNSANSTMHLKIEHEPIILHQYNKVAADLRETAVVVCKVQAYPKPEFQWTFGTNTA
PISMSSDAHYEINTQSDNNDIYTSTLKIHNVRHNDYGEYNCRASNSLETIRAPIRLQPKG
APEKPTNLDAADIGSNYISLNWTPGFDGGLSNTKFFVLYRKVSIPSNEVNGDCGSYYTSS
PDWSEFDCHRNYPCNITPLDQHSSYVFKVKAMNTKGNSEYSSEITKTTKVSKIPSALRVS
YDPSTKMLGINVGQTCLALTAVVETMLHAETHVPEWHIVGQIPLQASGNAPTFKESIVEN
IIIPRRSAARSLEDEEDFTMALEDESMPRVRVKLCLRGNPEHCGEYIGAEIGPSYIQDVA
SINMPTLVAIVVSCIVFALFIGLLLMFCRCKKKQTKKSVQAKDYEMDSVRPSIVAQQNQA
PPPYYPASGLENKALEHSMDLALAMEDQKTAIYATQNGYGYNSGLQVPSHNIPPDWVNMG
YMENSYSNSNNGGSVNSQDSLYQMKMSAAASNSGNLISQHHQYVERQQPSYGYDPLTHGG
YGTVDDDYATYPHLATTPSQQMIADDYHNQMMMAQQPPSRQDYCSDPYAAVHKPNKKRLD
SHMESPYHDVSGLPDPYMEQQMNMGEDQLDHPKPPQHLPQHLGGYDENLESGYSTPNSRN
RRVIREIIV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 36 | g6191.t1 | CDD | cd00096 | Ig | 253 | 307 | 1.11979E-8 |
| 38 | g6191.t1 | CDD | cd00096 | Ig | 337 | 388 | 8.92703E-8 |
| 37 | g6191.t1 | CDD | cd00096 | Ig | 432 | 495 | 1.2961E-6 |
| 39 | g6191.t1 | CDD | cd00096 | Ig | 526 | 613 | 3.01012E-8 |
| 35 | g6191.t1 | CDD | cd00096 | Ig | 637 | 715 | 6.5894E-11 |
| 40 | g6191.t1 | CDD | cd00063 | FN3 | 722 | 828 | 2.196E-11 |
| 26 | g6191.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 26 | 133 | 1.4E-9 |
| 22 | g6191.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 134 | 236 | 3.6E-22 |
| 23 | g6191.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 237 | 318 | 1.3E-14 |
| 25 | g6191.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 319 | 393 | 1.2E-13 |
| 20 | g6191.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 413 | 511 | 3.0E-14 |
| 27 | g6191.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 512 | 625 | 1.5E-22 |
| 24 | g6191.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 626 | 714 | 1.6E-19 |
| 21 | g6191.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 715 | 835 | 8.8E-16 |
| 8 | g6191.t1 | PANTHER | PTHR11640:SF134 | ECHINOID, ISOFORM A-RELATED | 7 | 1269 | 0.0 |
| 9 | g6191.t1 | PANTHER | PTHR11640 | NEPHRIN | 7 | 1269 | 0.0 |
| 4 | g6191.t1 | Pfam | PF13927 | Immunoglobulin domain | 134 | 214 | 2.0E-11 |
| 3 | g6191.t1 | Pfam | PF13927 | Immunoglobulin domain | 235 | 302 | 4.0E-9 |
| 2 | g6191.t1 | Pfam | PF13927 | Immunoglobulin domain | 320 | 388 | 1.1E-11 |
| 7 | g6191.t1 | Pfam | PF13895 | Immunoglobulin domain | 418 | 493 | 3.7E-11 |
| 5 | g6191.t1 | Pfam | PF13927 | Immunoglobulin domain | 506 | 603 | 1.6E-7 |
| 1 | g6191.t1 | Pfam | PF13927 | Immunoglobulin domain | 620 | 705 | 3.2E-13 |
| 6 | g6191.t1 | Pfam | PF00041 | Fibronectin type III domain | 724 | 821 | 1.5E-9 |
| 30 | g6191.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 25 | - |
| 31 | g6191.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 8 | - |
| 32 | g6191.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 9 | 20 | - |
| 34 | g6191.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 21 | 25 | - |
| 29 | g6191.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 26 | 966 | - |
| 33 | g6191.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 967 | 988 | - |
| 28 | g6191.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 989 | 1269 | - |
| 58 | g6191.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 34 | 127 | 7.976 |
| 59 | g6191.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 134 | 228 | 13.947 |
| 63 | g6191.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 235 | 313 | 11.098 |
| 61 | g6191.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 320 | 402 | 12.913 |
| 62 | g6191.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 414 | 500 | 10.825 |
| 60 | g6191.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 507 | 617 | 11.624 |
| 57 | g6191.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 620 | 717 | 10.154 |
| 56 | g6191.t1 | ProSiteProfiles | PS50853 | Fibronectin type-III domain profile. | 724 | 831 | 15.408 |
| 46 | g6191.t1 | SMART | SM00409 | IG_3c | 27 | 129 | 0.11 |
| 45 | g6191.t1 | SMART | SM00409 | IG_3c | 140 | 232 | 1.3E-6 |
| 51 | g6191.t1 | SMART | SM00408 | igc2_5 | 146 | 217 | 1.5E-6 |
| 44 | g6191.t1 | SMART | SM00409 | IG_3c | 242 | 317 | 1.8E-5 |
| 54 | g6191.t1 | SMART | SM00408 | igc2_5 | 248 | 305 | 0.0017 |
| 42 | g6191.t1 | SMART | SM00409 | IG_3c | 326 | 411 | 2.6E-6 |
| 53 | g6191.t1 | SMART | SM00408 | igc2_5 | 332 | 391 | 0.0019 |
| 43 | g6191.t1 | SMART | SM00409 | IG_3c | 421 | 504 | 1.8E-9 |
| 50 | g6191.t1 | SMART | SM00408 | igc2_5 | 427 | 492 | 2.6E-6 |
| 48 | g6191.t1 | SMART | SM00409 | IG_3c | 514 | 617 | 5.6 |
| 52 | g6191.t1 | SMART | SM00408 | igc2_5 | 521 | 606 | 0.0011 |
| 47 | g6191.t1 | SMART | SM00409 | IG_3c | 626 | 719 | 3.5E-5 |
| 55 | g6191.t1 | SMART | SM00408 | igc2_5 | 632 | 708 | 1.1E-7 |
| 49 | g6191.t1 | SMART | SM00060 | FN3_2 | 722 | 818 | 1.0E-8 |
| 16 | g6191.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 34 | 136 | 8.68E-8 |
| 13 | g6191.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 131 | 235 | 1.67E-17 |
| 12 | g6191.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 231 | 321 | 8.32E-14 |
| 11 | g6191.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 316 | 398 | 1.67E-13 |
| 15 | g6191.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 417 | 510 | 1.82E-13 |
| 17 | g6191.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 502 | 620 | 2.53E-12 |
| 14 | g6191.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 620 | 726 | 2.65E-17 |
| 10 | g6191.t1 | SUPERFAMILY | SSF49265 | Fibronectin type III | 711 | 833 | 7.76E-16 |
| 19 | g6191.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 25 | - |
| 18 | g6191.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 25 | - |
| 41 | g6191.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 966 | 988 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K16680 (echinoid)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
