General information for g6203.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Hyaluronidase Tab y 2.0101.
Parent gene
- The parent gene g6203 is located on chr_2: 15246801..15248362 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6203 | g6203.t1 | isoform | g6203.t1 | 15246801 | 15248362 |
| chr_2 | g6203 | g6203.t1 | exon | g6203.t1.exon1 | 15246801 | 15246856 |
| chr_2 | g6203 | g6203.t1 | cds | g6203.t1.CDS1 | 15246801 | 15246856 |
| chr_2 | g6203 | g6203.t1 | exon | g6203.t1.exon2 | 15246926 | 15247042 |
| chr_2 | g6203 | g6203.t1 | cds | g6203.t1.CDS2 | 15246926 | 15247042 |
| chr_2 | g6203 | g6203.t1 | exon | g6203.t1.exon3 | 15247102 | 15247798 |
| chr_2 | g6203 | g6203.t1 | cds | g6203.t1.CDS3 | 15247102 | 15247798 |
| chr_2 | g6203 | g6203.t1 | exon | g6203.t1.exon4 | 15248207 | 15248362 |
| chr_2 | g6203 | g6203.t1 | cds | g6203.t1.CDS4 | 15248207 | 15248362 |
| chr_2 | g6203 | g6203.t1 | TSS | g6203.t1 | NA | NA |
| chr_2 | g6203 | g6203.t1 | TTS | g6203.t1 | NA | NA |
Sequences
>g6203.t1 Gene=g6203 Length=1026
ATGCCTTATTTTTTACTGCTGCTATACAACTTGTTATTTCGAGTTACAGAATCAAACAGT
TTCAATGTCCATTGGGCAGTTCCAACGAGCAATTGTCGTAAATTTAAAGTTGACTTTTCG
GACATTGCTCTGACGAATAAAAATATAATTCAAAACACTAATGACACTGTAAGAGGCGAT
AAAATCGTGATTCTATACGATCCAGGTGAATGGCCTAAAATTGATATTGATCAGAATGGA
AAGTTACAATATCAAAATGGTGGTCTTCCTCAGAATAGCAGTCTTGATATTCATTTGCGA
CAATTTCAAATTGATATTGATCGATTGATTCCAAATAAAACTTTTGATGGTTTAGCAGTA
ATCGATTTTGAATGTTGGCGGCCAATTTTTAGACAAAATTTTGGCGATTTGAAACTTTAC
CGTGAATTAACACTTTTACAAGTGAATAAAAAACATCCGACATGGACAAAAGATCAAGTT
GAGGCACAAGCGAAAATAATTTTTGAAAATGCAGCTTTCAATTTTATAAATCGAACAATG
CTGAGAGCAAAAAAACTTCGACCTAATGCGAAGTGGGGATTTTATGGATTTCCTCATTGT
TTTAATCGTTATAGAAGTTTCAATCAATTGGAAAAATGTCCAGATATTGTAGAAGAAGAA
AATAATAGACTTTTATTCATGTATAGTGATGTTATTTATCCTTCAATTTATATCACAAAC
AATCAATCTGATACAGCTCTAACAAAGTTTGTTCAGGGAAAAATGTATGAAACACAAAGA
ATTACTCAATTAATCAACAATCCTAATACTGTGAAGAAGCTACCATTTGTACGATATGAA
TATACAGATATATCTGGATTTATGAAAAAAGCTGATATGATGAACATACTGAAGACAATA
AAGTCAGAAGGCGGCGATGGCGTCATACTTTGGGGCAGCTCATCACAATTCAAAAATGAA
TCACAATGCCGTGCATTTAAAGACTATTATGAGCGCAACATTGTAAATATAATTAAAGAT
CTTTAA
>g6203.t1 Gene=g6203 Length=341
MPYFLLLLYNLLFRVTESNSFNVHWAVPTSNCRKFKVDFSDIALTNKNIIQNTNDTVRGD
KIVILYDPGEWPKIDIDQNGKLQYQNGGLPQNSSLDIHLRQFQIDIDRLIPNKTFDGLAV
IDFECWRPIFRQNFGDLKLYRELTLLQVNKKHPTWTKDQVEAQAKIIFENAAFNFINRTM
LRAKKLRPNAKWGFYGFPHCFNRYRSFNQLEKCPDIVEEENNRLLFMYSDVIYPSIYITN
NQSDTALTKFVQGKMYETQRITQLINNPNTVKKLPFVRYEYTDISGFMKKADMMNILKTI
KSEGGDGVILWGSSSQFKNESQCRAFKDYYERNIVNIIKDL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g6203.t1 | Gene3D | G3DSA:3.20.20.70 | Aldolase class I | 14 | 340 | 2.0E-104 |
| 2 | g6203.t1 | PANTHER | PTHR11769:SF35 | HYALURONIDASE | 14 | 334 | 1.0E-83 |
| 3 | g6203.t1 | PANTHER | PTHR11769 | HYALURONIDASE | 14 | 334 | 1.0E-83 |
| 21 | g6203.t1 | PIRSF | PIRSF038193 | Hyaluronidase | 3 | 339 | 3.9E-53 |
| 8 | g6203.t1 | PRINTS | PR00846 | Glycosyl hydrolase family 56 signature | 21 | 33 | 2.3E-21 |
| 12 | g6203.t1 | PRINTS | PR00847 | Bee venom hyaluronidase signature | 62 | 75 | 1.5E-10 |
| 5 | g6203.t1 | PRINTS | PR00846 | Glycosyl hydrolase family 56 signature | 85 | 99 | 2.3E-21 |
| 11 | g6203.t1 | PRINTS | PR00847 | Bee venom hyaluronidase signature | 106 | 119 | 1.5E-10 |
| 6 | g6203.t1 | PRINTS | PR00846 | Glycosyl hydrolase family 56 signature | 117 | 134 | 2.3E-21 |
| 9 | g6203.t1 | PRINTS | PR00847 | Bee venom hyaluronidase signature | 149 | 164 | 1.5E-10 |
| 7 | g6203.t1 | PRINTS | PR00846 | Glycosyl hydrolase family 56 signature | 175 | 200 | 2.3E-21 |
| 10 | g6203.t1 | PRINTS | PR00847 | Bee venom hyaluronidase signature | 313 | 323 | 1.5E-10 |
| 4 | g6203.t1 | PRINTS | PR00846 | Glycosyl hydrolase family 56 signature | 323 | 336 | 2.3E-21 |
| 1 | g6203.t1 | Pfam | PF01630 | Hyaluronidase | 16 | 338 | 9.3E-86 |
| 17 | g6203.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 18 | - |
| 18 | g6203.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 3 | - |
| 19 | g6203.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 4 | 13 | - |
| 20 | g6203.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 14 | 18 | - |
| 16 | g6203.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 19 | 341 | - |
| 13 | g6203.t1 | SUPERFAMILY | SSF51445 | (Trans)glycosidases | 21 | 335 | 7.58E-90 |
| 14 | g6203.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006952 | defense response | BP |
| GO:0005975 | carbohydrate metabolic process | BP |
| GO:0003824 | catalytic activity | MF |
| GO:0004415 | hyalurononglucosaminidase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01197 (hyaluronoglucosaminidase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed