Gene loci information

Transcript annotation

  • This transcript has been annotated as Glutathione S-transferase 1, isoform D.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_2 g6245 g6245.t1 TTS g6245.t1 15599218 15599218
chr_2 g6245 g6245.t1 isoform g6245.t1 15599310 15600017
chr_2 g6245 g6245.t1 exon g6245.t1.exon1 15599310 15599935
chr_2 g6245 g6245.t1 cds g6245.t1.CDS1 15599310 15599935
chr_2 g6245 g6245.t1 exon g6245.t1.exon2 15599993 15600017
chr_2 g6245 g6245.t1 cds g6245.t1.CDS2 15599993 15600017
chr_2 g6245 g6245.t1 TSS g6245.t1 15600055 15600055

Sequences

>g6245.t1 Gene=g6245 Length=651
ATGGGCGATCTCTATTATGTTCCAATTTCATCGCCATGTCGTCTAGTACAAATGACAGCT
GCTGCATTGAACATCAAGTTAAATCTTATAGAGATTGATCCATATCGAAAAGAACATTTA
AGACCAAGTTTTTTGAAATTAAATCCTCATCATACTGTGCCTGTTCTTGTTGATGGTGAT
TTTGTTCTTTATGAATCAAGACCAATTTGCATTTATTTAATTGAAAAATATAGTAAAGAT
GATTCACTTTATCCTCGTGATCCTAAAAGACGTGCAATTGTTAATCAAAGACTTTATTTT
GATATGGCGACACTCTTTCAAAGGTTTGCAGAATATTATTATCCTCAAGTATTAAAAAAA
TTACCGGCTGATAAGGAAAGATTAAAATCATTTGAAGAAGCAATGAAAATATTGGAATTA
TTTTTAGACAAACAAAAGTTTGTTGCGCATACAGATAAAATGACAATAGCTGATATCTCA
ATTGCTGCAACAATCAACACTTGTGAACTTGGTGGCTATAATTTGAGTAGATATCCAAAT
ATTTTCAAATGGTATACAATGATGAAAACTATTTGTCCTGGATGGAGTGTTAATTTAAAA
GCTGCTGGAATGATGAAGCACTATACTACCAAAATTTCTTATGATTTGTAA

>g6245.t1 Gene=g6245 Length=216
MGDLYYVPISSPCRLVQMTAAALNIKLNLIEIDPYRKEHLRPSFLKLNPHHTVPVLVDGD
FVLYESRPICIYLIEKYSKDDSLYPRDPKRRAIVNQRLYFDMATLFQRFAEYYYPQVLKK
LPADKERLKSFEEAMKILELFLDKQKFVAHTDKMTIADISIAATINTCELGGYNLSRYPN
IFKWYTMMKTICPGWSVNLKAAGMMKHYTTKISYDL

Protein features from InterProScan

Transcript Database ID Name Start End E.value
12 g6245.t1 CDD cd03045 GST_N_Delta_Epsilon 3 75 0.000000
11 g6245.t1 CDD cd03177 GST_C_Delta_Epsilon 89 206 0.000000
8 g6245.t1 Gene3D G3DSA:3.40.30.10 Glutaredoxin 2 79 0.000000
7 g6245.t1 Gene3D G3DSA:1.20.1050.10 - 80 211 0.000000
3 g6245.t1 PANTHER PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED 2 208 0.000000
4 g6245.t1 PANTHER PTHR43969 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED 2 208 0.000000
1 g6245.t1 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 78 0.000000
2 g6245.t1 Pfam PF14497 Glutathione S-transferase, C-terminal domain 108 189 0.000014
10 g6245.t1 ProSiteProfiles PS50404 Soluble glutathione S-transferase N-terminal domain profile. 1 81 20.701000
9 g6245.t1 ProSiteProfiles PS50405 Soluble glutathione S-transferase C-terminal domain profile. 87 212 18.036000
13 g6245.t1 SFLD SFLDG01153 Main.4: Theta-like 3 210 0.000000
14 g6245.t1 SFLD SFLDS00019 Glutathione Transferase (cytosolic) 3 210 0.000000
5 g6245.t1 SUPERFAMILY SSF52833 Thioredoxin-like 3 85 0.000000
6 g6245.t1 SUPERFAMILY SSF47616 GST C-terminal domain-like 87 190 0.000000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006749 glutathione metabolic process BP
GO:0005515 protein binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed