General information for g6357.t11
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Cathepsin L-like.
Parent gene
- The parent gene g6357 is located on chr_2: 16467612..16468633 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6357 | g6357.t11 | TTS | g6357.t11 | 16466747 | 16466747 |
| chr_2 | g6357 | g6357.t11 | isoform | g6357.t11 | 16466970 | 16468633 |
| chr_2 | g6357 | g6357.t11 | exon | g6357.t11.exon1 | 16466970 | 16467062 |
| chr_2 | g6357 | g6357.t11 | cds | g6357.t11.CDS1 | 16466970 | 16467062 |
| chr_2 | g6357 | g6357.t11 | exon | g6357.t11.exon2 | 16467166 | 16467533 |
| chr_2 | g6357 | g6357.t11 | cds | g6357.t11.CDS2 | 16467166 | 16467453 |
| chr_2 | g6357 | g6357.t11 | exon | g6357.t11.exon3 | 16468009 | 16468123 |
| chr_2 | g6357 | g6357.t11 | exon | g6357.t11.exon4 | 16468183 | 16468633 |
| chr_2 | g6357 | g6357.t11 | TSS | g6357.t11 | 16468659 | 16468659 |
Sequences
>g6357.t11 Gene=g6357 Length=1027
ATGAATTACAAATTAATTTTTATTTCATCATTTTTGTTAATTTCACAATCAACGCAATTA
TTTATTGACAATCCAAAACTTTCCACATGGATGATGGAAAATGGTGAAAAGTTTTTTAAT
CTTAGTGAATCAATTCTAACAAAAGTGCAACAAAGTGTGCTAGACAATTTACAAATTATT
GAAAAACACAATAAGGAAGTGAGCGATTTTATACTTGGATTAAATGAATTTTCTGATTTA
GATAAAAAAGAATTTGTGAAATGTTATTGCAAAACTGTAATGCCAAAACAATTTTTACCT
GATCGACCAAAGCTGGCGAGAGCTAAAGCATTGAATAATTTTACTATTGATAATTTACCA
GAATCATTTAGTTGGAAGGAGCATTTTGAACGTGTGAAAATGCAAGGAAAATGTGGAAGT
TGTTATGCATTTTCTGTCACTTCTATGTTAGAGGCAATGAATAAAAAGAAAAATAGTAGC
TGGAATTATGAATTATCACCACAATATATTCTTGATTGTGATAGTAAAAATGATGGTTGT
GACGGTAAGAAATATTTTTTAATTTATGTTTTTAAAATATAAATCTAAAAATGAAGCTCC
AACACTAGAAAATTATCCATATATTAAAAAACAAAAAGAATGTAAAATGACTGGTTTCCC
AAAAGTAAAACTCAATATTGATGAAGTTTTTGAATTTAAATTTAGAGGCGATGAAAAACA
AATGAGACTTCACTTAGTTAATTATGGTCCATTAGTTATAACTATGCATGTCAATGATGA
CACAGGTTTATTTCAAAACTACAAGAAAGGAATTTTCTATGAAAAAGAATGCTCAAATGA
TTGTAAAATAATTAATCATGCAATGGTTTTGATTGGATATGGAGTCACAAATGATGATGA
AAAGAAACCTTATTATTTAGTTTTAAATTCTTGGGGAAAGTCATGGGGTGAAGAAGGTTA
TATTCGGATGGCAGCTGATCGAGGAAATAATTGCAATGTTGCTTGCTTTGGAGTTGTTGC
TACTTAA
>g6357.t11 Gene=g6357 Length=126
MTGFPKVKLNIDEVFEFKFRGDEKQMRLHLVNYGPLVITMHVNDDTGLFQNYKKGIFYEK
ECSNDCKIINHAMVLIGYGVTNDDEKKPYYLVLNSWGKSWGEEGYIRMAADRGNNCNVAC
FGVVAT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g6357.t11 | Gene3D | G3DSA:3.90.70.10 | Cysteine proteinases | 5 | 125 | 2.8E-31 |
| 2 | g6357.t11 | PANTHER | PTHR12411 | CYSTEINE PROTEASE FAMILY C1-RELATED | 21 | 121 | 3.4E-19 |
| 3 | g6357.t11 | PANTHER | PTHR12411:SF774 | CATHEPSIN K | 21 | 121 | 3.4E-19 |
| 1 | g6357.t11 | Pfam | PF00112 | Papain family cysteine protease | 17 | 120 | 2.8E-26 |
| 6 | g6357.t11 | ProSitePatterns | PS00639 | Eukaryotic thiol (cysteine) proteases histidine active site. | 69 | 79 | - |
| 5 | g6357.t11 | SMART | SM00645 | pept_c1 | 2 | 126 | 2.9E-4 |
| 4 | g6357.t11 | SUPERFAMILY | SSF54001 | Cysteine proteinases | 15 | 119 | 3.33E-32 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008234 | cysteine-type peptidase activity | MF |
| GO:0006508 | proteolysis | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed