General information for g6398.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Glutathione S-transferase.
Parent gene
- The parent gene g6398 is located on chr_2: 16860120..16862852 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6398 | g6398.t2 | isoform | g6398.t2 | 16860120 | 16862852 |
| chr_2 | g6398 | g6398.t2 | exon | g6398.t2.exon1 | 16860120 | 16860287 |
| chr_2 | g6398 | g6398.t2 | cds | g6398.t2.CDS1 | 16860120 | 16860287 |
| chr_2 | g6398 | g6398.t2 | exon | g6398.t2.exon2 | 16860345 | 16860487 |
| chr_2 | g6398 | g6398.t2 | cds | g6398.t2.CDS2 | 16860345 | 16860487 |
| chr_2 | g6398 | g6398.t2 | exon | g6398.t2.exon3 | 16860549 | 16860734 |
| chr_2 | g6398 | g6398.t2 | cds | g6398.t2.CDS3 | 16860549 | 16860717 |
| chr_2 | g6398 | g6398.t2 | exon | g6398.t2.exon4 | 16861346 | 16861462 |
| chr_2 | g6398 | g6398.t2 | exon | g6398.t2.exon5 | 16862369 | 16862852 |
| chr_2 | g6398 | g6398.t2 | TSS | g6398.t2 | NA | NA |
| chr_2 | g6398 | g6398.t2 | TTS | g6398.t2 | NA | NA |
Sequences
>g6398.t2 Gene=g6398 Length=1098
TTAAGCGAATAAAATTAAACGTTCTAATCGTGATTCATGTGTGCCATATAATGAATCAGG
TGAACATGTGTATGATTCTGTGACATAACATGAGCCATCATCACATTTTGCAGAAATTAC
AACTTTATCTTCTTCAGATTTGTTCCATGGCTGATTAAACATTGAAATAGTGCAGACTTT
TTTCGTGCCTTCAACTACATAATCACCTTTGATTCTAAACAGATATCCGGCAACTACTTG
CTGAGTTATATATTCTATGTTGCTAATTACAATTTCTTGTCTATCACCAGTAATTAATCG
GTTGAGATGTTGAGTCAAAAGTTTATTCGCATAGCTATCATTAATGTCAAGTGTACGAGG
TGCTCCAACAATATATTCTTTAACGTGTTTAACTTCATTAGTCATCTGATTGTCATCATC
AAGAATAAAAGGTCTTTTAAGTCGCTTTTTGATGTGCTGGTGGGATAAAAAAATTTTACA
ACGTATAATCATGCCAGAATATAAAGTTTTTTACTTTAATGTAAAAGCTCTCGGTGAGCC
ACTTCGTTTCTTGCTCTCATATGGAAATTTACCCTTTGAGGATGTTCGTATTTCCAGGTG
ATCTCCGCTATCAAAGGCATGCCTATGAATCAGTTGCCTGTTTTGGAAGTTGATGGAAAG
CGTGTAAATCAGTCGCTTGCATGCTGCCGTTTTATTGCCAAAACTATTGGTTCCCTTGCT
GGTAACGATGACTGGGAAAATTTACAAATTGACACTGTTGCAGATACTGTCAATGATTTC
CGTCTAAAAATTGCTGTGGTTTCATATGAACCAGATGATGAAGTTAAGGAAAAGAAGCTT
CAAACTTTGAATAATGAAGTTATTCCATTTTATTTGGAAAAATTAGAAGATATTGCACGA
GAAAATGGTGGATATTTATCACTTGGCCGACTTACATGGGCTGATTTCTATTTTGCAGGA
ATTATTGAATATCTCAACTATTTAGCCAAACAAGATTTAACAGCCAATCATGAAAATTTG
AGAAAAGTCGTTGATAATGTTATCAATCAGAGTCAAGTTCAAGAATGGATTGCAAAGAGA
CCACAAACTGATATCTAA
>g6398.t2 Gene=g6398 Length=159
MPMNQLPVLEVDGKRVNQSLACCRFIAKTIGSLAGNDDWENLQIDTVADTVNDFRLKIAV
VSYEPDDEVKEKKLQTLNNEVIPFYLEKLEDIARENGGYLSLGRLTWADFYFAGIIEYLN
YLAKQDLTANHENLRKVVDNVINQSQVQEWIAKRPQTDI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g6398.t2 | CDD | cd03192 | GST_C_Sigma_like | 39 | 141 | 2.74901E-29 |
| 8 | g6398.t2 | Coils | Coil | Coil | 124 | 144 | - |
| 7 | g6398.t2 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 1 | 36 | 2.5E-7 |
| 6 | g6398.t2 | Gene3D | G3DSA:1.20.1050.10 | - | 37 | 143 | 7.0E-42 |
| 2 | g6398.t2 | PANTHER | PTHR11571:SF234 | GLUTATHIONE S-TRANSFERASE S1 | 1 | 159 | 4.1E-64 |
| 3 | g6398.t2 | PANTHER | PTHR11571 | GLUTATHIONE S-TRANSFERASE | 1 | 159 | 4.1E-64 |
| 1 | g6398.t2 | Pfam | PF14497 | Glutathione S-transferase, C-terminal domain | 52 | 154 | 2.3E-16 |
| 11 | g6398.t2 | ProSiteProfiles | PS50404 | Soluble glutathione S-transferase N-terminal domain profile. | 1 | 34 | 11.53 |
| 10 | g6398.t2 | ProSiteProfiles | PS50405 | Soluble glutathione S-transferase C-terminal domain profile. | 37 | 159 | 19.203 |
| 12 | g6398.t2 | SFLD | SFLDS00019 | Glutathione Transferase (cytosolic) | 1 | 142 | 6.8E-22 |
| 4 | g6398.t2 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 1 | 30 | 1.66E-5 |
| 5 | g6398.t2 | SUPERFAMILY | SSF47616 | GST C-terminal domain-like | 33 | 158 | 2.13E-29 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006749 | glutathione metabolic process | BP |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
