General information for g6489.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Peroxidase.
Parent gene
- The parent gene g6489 is located on chr_2: 17243932..17249327 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6489 | g6489.t1 | TSS | g6489.t1 | 17239431 | 17239431 |
| chr_2 | g6489 | g6489.t1 | isoform | g6489.t1 | 17239481 | 17243932 |
| chr_2 | g6489 | g6489.t1 | exon | g6489.t1.exon1 | 17239481 | 17240556 |
| chr_2 | g6489 | g6489.t1 | cds | g6489.t1.CDS1 | 17239481 | 17240556 |
| chr_2 | g6489 | g6489.t1 | exon | g6489.t1.exon2 | 17240624 | 17240951 |
| chr_2 | g6489 | g6489.t1 | cds | g6489.t1.CDS2 | 17240624 | 17240951 |
| chr_2 | g6489 | g6489.t1 | exon | g6489.t1.exon3 | 17241013 | 17241320 |
| chr_2 | g6489 | g6489.t1 | cds | g6489.t1.CDS3 | 17241013 | 17241320 |
| chr_2 | g6489 | g6489.t1 | exon | g6489.t1.exon4 | 17241379 | 17241436 |
| chr_2 | g6489 | g6489.t1 | cds | g6489.t1.CDS4 | 17241379 | 17241436 |
| chr_2 | g6489 | g6489.t1 | TTS | g6489.t1 | 17241574 | 17241574 |
| chr_2 | g6489 | g6489.t1 | exon | g6489.t1.exon5 | 17241961 | 17242001 |
| chr_2 | g6489 | g6489.t1 | cds | g6489.t1.CDS5 | 17241961 | 17242001 |
| chr_2 | g6489 | g6489.t1 | exon | g6489.t1.exon6 | 17242383 | 17242767 |
| chr_2 | g6489 | g6489.t1 | cds | g6489.t1.CDS6 | 17242383 | 17242767 |
| chr_2 | g6489 | g6489.t1 | exon | g6489.t1.exon7 | 17242829 | 17243528 |
| chr_2 | g6489 | g6489.t1 | cds | g6489.t1.CDS7 | 17242829 | 17243528 |
| chr_2 | g6489 | g6489.t1 | exon | g6489.t1.exon8 | 17243625 | 17243932 |
| chr_2 | g6489 | g6489.t1 | cds | g6489.t1.CDS8 | 17243625 | 17243932 |
Sequences
>g6489.t1 Gene=g6489 Length=3204
ATGAAAATTTTAATTCTTATCGCGGCGGCAGTAATAACTGCAAGTGTGGATGCAGATGAT
TGTGTTAGTCACACTTATCGAACATTAGATGGTTCATGCAACAATTTAAAACATCCTAAT
TGGGGTAAAGCTGGAACTCCATATGCTCGACTTTTGCCAGCACGTTATGGTGATGGAATT
TTCAGTCCACCAAAGTCAAAAACGGGTGCTGATTTGCCAAGCTCAAGACTTGTATCGACT
ACGATTTTTGATACTATTGATTCACCTGATCCCAATCATACAATTGTCACTATGCAATTT
GGTCAATTTGTTGCACATGATATGAGTTTTGGTGGGGCACCTATTCATCCATCATGCTGC
CAAGATGGAAAAATTGTCTCTCATGATCCATTATGTTATCCAATTATTGTTCCAAATGAC
GACCCAGTTCGCTCAGCCGATGGCATCGAATGTATGAATTTTCAACGCACATTAACCGAC
AGAGATAACGAACTTGATGAAAACCGAGCAAATCAACCTGCACAGCAGATAACAGTTGTG
ACAGGCTTTCTTGACCTTTCTCTCGTGTATGGAAACTCCGAGAAAGAATTAGCGCCCGTA
AGAGAATTTAATGCAGGACGTTTAAAGATGGATATCCGTAATGGAAAAGAATGGCCACCA
CATAACCCTGATGGTGATAAAATTTGTTTTGTTGAGACATCTGGAGAGACTTGCTACTTC
GGAGGCGACCCACGTCTAAATCAAAGTCCTGATTTATCAATTCTTCATATTTATTATATT
CGTGAGCATAATCGACTTGCAGGAATCTTACATGAAATGAATCCAAGTTGGTCAGATGAG
AAACTTTTCCAAGAAGCTCGTCGCATTAATATTGCTCAATATCAATATGTTGTTTATTAT
GAATGGTTGCCATTGTTATTGGGAGAACAAAATATGTTTAAAGCTAAATTGATTTATTAT
AAAGATGGTGGTGAATATGTTGATGACTATGATGAAAATGTTGATCCATCAGCACTCAAT
GATCATGCTGCTTCTGCCTTCCGTTATTTCCATTCTGAAATTGAAGGAAATTTAGAATTA
ATTTCAGAATCACGTGAATGCAAGAAATCAATGAAAATCAGTGATGTGTTCTTACGACCA
AAAATTTTGGAGCAAAATGATAACTTCGATTCTTTTGCACGTGGTATGGCAACTCAAAGA
TTCCAAAAACCTGACAAATACTTTGACATTGAAGTTAGAGAATTTCTTCTTAAGCATTTG
CGCAAATATGGTGATGACATTAGAGCAATTGATATTCAAAGAGGCAGAGATCATGGCATT
GCTAGTTATAACAGTTTCAGAGAATTCTGTGATCTTCCAAAAGCTACAAAATGGGAAGAT
TATTTGGATTTGATTTCTCAAGAAGATATTGATAAATTGAAATCAATTTACCCAAGCTAT
GATGACGTTGACTTGTCAGTTGGTGGAATTCTTGAAAAACGTGTTGATAAATCAACTTTA
ACTAATCCAACTTATTATTGCATTTATATGAAACAATTTTATAATACTCGTGTTGGTGAT
CGCTATTGGTTTGAAAGAAGTGATCCCGAATTTGCATTTACCACATCACAATTGGCTGAA
ATAAGAAAATCAAGCATGTCGAGAATTTTCTGTGACAATGGTAATAATATTTTGAGTATG
CAACCAAATGCCTTCGTTGTTCCATCTGAAAGCAACAAAGTCATTCCATGCACAGAAATT
CCAGCTATTGATTACACTTTATGGCGAGATTTGTTATTTGATCGTAAGAGTGTGAAGATC
AGATACTTGAGAATGTCAAATAATATCTACATTAAAAATGCATGTGTAGTAAATCACGAC
ACGATACAAGAAAATGTGTCAATTTATGTTGAGAATGGTGTCATAAAATTTATTGGTACT
GAATGTGATTTTCCGATTCCGACTAATATTGAAGTGATTGATGCAAGTGGAAAGTATGTA
ATACCCGGTGGAATTGATCCGCATACTCATTTTGAGTTAGAATTTGGTGGTACATTTGCT
GTTGATGATTTTTATCAAGGTACGTGTGCTGCAGTGGCAGGTGGAACAACCACAATCATT
GATTTTGTTATACCTAAGAAAGGACAATCGATTCTTGAAGCATATGAAATTTGGCGAAAA
AGAGCTGATTCAAAAGTTGTCTGTGACTATGGATTGCATTGTGCAATAACATGGTGGAGT
GTGGAAGTTAATAAAGATATGGAAATTTTGGCAAAAGAGAAAGGAATCAGTTCATTTAAA
ATGTTTATGGCTTATAAAGGATTATTTATGCTTGATGATAGTGAACTTTATGAAACATTT
GAACGTTGTCGAGATATAGGAGCATTAGCGCAAGTCCATGCTGAGAATGGAGACATTATT
GCGAAAAATACGAAAAAATTACTTGAAAATGGTGTTAAAGGACCAGAAGGCCATCAACTT
TCACGAACAGAAGACGTTGAAGCTGAAGCTACAAATCGAGCATGTGTCATTGCTCATCAA
ACAAATTGTCCACTTTATGTTGTTCATGTTATGTCAATTTCAGCAGCAGAAGAAGTCGCA
AGAGCGCGTGAACGATGGGGAAAGAATTTTATTTTTGGAGAAACTTTAGCAGCTGCTCTT
GGTGCAAGCGGTGAAGAATATTACGATAAATGTTGGCATCATGCAGCTGCTCATGTTTTA
TCACCTCCATTGCGACCGAGAAAAGAAACACGTGAAGTTTTAATGAAAATGCTAGCAAAT
GATGATCTTCAATCTACTGGTTCTGATAATTGTACTTTTAACAAGAAGCAGAAGGAACTT
GGACTTGATGATTTTTCAAAAATTCCTAATGGTGTAAATGGCGTGGAAGATCGAATGAGT
GTCATTTGGGAAAAAGGGGGGGGAACTGACATTTTTTGTGCAGCGAAAATATTCAATCTA
TATCCAAAGAAAGGAAGTTTGACAGTTGGAGCTGATGCTGATATTGTCATCTGGAATTAT
AAAGATACTAGAACTATTTCAGTTAAAACACATCATCATGCATGCGATTTTAATATTTTT
GAAGGAATGGTTTGTCATGGTGTACCTGAAATTGTCATTGTTGGCGGAAAAATTTGTGTC
CGTGATGGAAAATTGAGTGTTACTCCCGGATCAGGAAAATTTTTACCAAGAAATGCTTTT
AATACGTTTATTTTTAAATCATAA
>g6489.t1 Gene=g6489 Length=1067
MKILILIAAAVITASVDADDCVSHTYRTLDGSCNNLKHPNWGKAGTPYARLLPARYGDGI
FSPPKSKTGADLPSSRLVSTTIFDTIDSPDPNHTIVTMQFGQFVAHDMSFGGAPIHPSCC
QDGKIVSHDPLCYPIIVPNDDPVRSADGIECMNFQRTLTDRDNELDENRANQPAQQITVV
TGFLDLSLVYGNSEKELAPVREFNAGRLKMDIRNGKEWPPHNPDGDKICFVETSGETCYF
GGDPRLNQSPDLSILHIYYIREHNRLAGILHEMNPSWSDEKLFQEARRINIAQYQYVVYY
EWLPLLLGEQNMFKAKLIYYKDGGEYVDDYDENVDPSALNDHAASAFRYFHSEIEGNLEL
ISESRECKKSMKISDVFLRPKILEQNDNFDSFARGMATQRFQKPDKYFDIEVREFLLKHL
RKYGDDIRAIDIQRGRDHGIASYNSFREFCDLPKATKWEDYLDLISQEDIDKLKSIYPSY
DDVDLSVGGILEKRVDKSTLTNPTYYCIYMKQFYNTRVGDRYWFERSDPEFAFTTSQLAE
IRKSSMSRIFCDNGNNILSMQPNAFVVPSESNKVIPCTEIPAIDYTLWRDLLFDRKSVKI
RYLRMSNNIYIKNACVVNHDTIQENVSIYVENGVIKFIGTECDFPIPTNIEVIDASGKYV
IPGGIDPHTHFELEFGGTFAVDDFYQGTCAAVAGGTTTIIDFVIPKKGQSILEAYEIWRK
RADSKVVCDYGLHCAITWWSVEVNKDMEILAKEKGISSFKMFMAYKGLFMLDDSELYETF
ERCRDIGALAQVHAENGDIIAKNTKKLLENGVKGPEGHQLSRTEDVEAEATNRACVIAHQ
TNCPLYVVHVMSISAAEEVARARERWGKNFIFGETLAAALGASGEEYYDKCWHHAAAHVL
SPPLRPRKETREVLMKMLANDDLQSTGSDNCTFNKKQKELGLDDFSKIPNGVNGVEDRMS
VIWEKGGGTDIFCAAKIFNLYPKKGSLTVGADADIVIWNYKDTRTISVKTHHHACDFNIF
EGMVCHGVPEIVIVGGKICVRDGKLSVTPGSGKFLPRNAFNTFIFKS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 27 | g6489.t1 | CDD | cd09823 | peroxinectin_like | 174 | 553 | 1.39097E-171 |
| 26 | g6489.t1 | CDD | cd01314 | D-HYD | 609 | 1052 | 0.0 |
| 19 | g6489.t1 | Gene3D | G3DSA:1.10.640.10 | Myeloperoxidase | 9 | 591 | 1.9E-182 |
| 18 | g6489.t1 | Gene3D | G3DSA:2.30.40.10 | Urease | 609 | 1066 | 2.4E-190 |
| 20 | g6489.t1 | Gene3D | G3DSA:3.20.20.140 | - | 663 | 1026 | 2.4E-190 |
| 3 | g6489.t1 | PANTHER | PTHR11475 | OXIDASE/PEROXIDASE | 6 | 589 | 7.3E-255 |
| 4 | g6489.t1 | PANTHER | PTHR11475:SF86 | PEROXIDASE | 6 | 589 | 7.3E-255 |
| 6 | g6489.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 50 | 61 | 5.4E-30 |
| 9 | g6489.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 96 | 111 | 5.4E-30 |
| 10 | g6489.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 239 | 257 | 5.4E-30 |
| 11 | g6489.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 257 | 277 | 5.4E-30 |
| 12 | g6489.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 282 | 308 | 5.4E-30 |
| 8 | g6489.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 344 | 354 | 5.4E-30 |
| 5 | g6489.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 466 | 486 | 5.4E-30 |
| 7 | g6489.t1 | PRINTS | PR00457 | Animal haem peroxidase signature | 541 | 555 | 5.4E-30 |
| 1 | g6489.t1 | Pfam | PF03098 | Animal haem peroxidase | 26 | 565 | 3.8E-170 |
| 2 | g6489.t1 | Pfam | PF01979 | Amidohydrolase family | 659 | 1038 | 1.8E-22 |
| 22 | g6489.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 18 | - |
| 23 | g6489.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 2 | - |
| 24 | g6489.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 3 | 13 | - |
| 25 | g6489.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 14 | 18 | - |
| 21 | g6489.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 19 | 1067 | - |
| 30 | g6489.t1 | ProSiteProfiles | PS50292 | Animal heme peroxidase superfamily profile. | 18 | 592 | 137.452 |
| 13 | g6489.t1 | SUPERFAMILY | SSF48113 | Heme-dependent peroxidases | 21 | 590 | 5.47E-167 |
| 15 | g6489.t1 | SUPERFAMILY | SSF51338 | Composite domain of metallo-dependent hydrolases | 608 | 675 | 6.98E-12 |
| 14 | g6489.t1 | SUPERFAMILY | SSF51556 | Metallo-dependent hydrolases | 663 | 985 | 1.43E-86 |
| 16 | g6489.t1 | SUPERFAMILY | SSF51338 | Composite domain of metallo-dependent hydrolases | 973 | 1061 | 1.12E-33 |
| 17 | g6489.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
| 28 | g6489.t1 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
| 29 | g6489.t1 | TIGRFAM | TIGR02033 | D-hydantoinase: dihydropyrimidinase | 610 | 1057 | 9.6E-151 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0020037 | heme binding | MF |
| GO:0042600 | egg chorion | CC |
| GO:0055114 | NA | NA |
| GO:0005737 | cytoplasm | CC |
| GO:0006979 | response to oxidative stress | BP |
| GO:0016787 | hydrolase activity | MF |
| GO:0004601 | peroxidase activity | MF |
| GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | MF |
KEGG
Orthology
- This transcript has been annotated with K01464 (dihydropyrimidinase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
