General information for g6493.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Multiple inositol polyphosphate phosphatase 1.
Parent gene
- The parent gene g6493 is located on chr_2: 17254127..17255725 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6493 | g6493.t1 | TSS | g6493.t1 | 17253254 | 17253254 |
| chr_2 | g6493 | g6493.t1 | isoform | g6493.t1 | 17254127 | 17255725 |
| chr_2 | g6493 | g6493.t1 | exon | g6493.t1.exon1 | 17254127 | 17254304 |
| chr_2 | g6493 | g6493.t1 | cds | g6493.t1.CDS1 | 17254127 | 17254304 |
| chr_2 | g6493 | g6493.t1 | exon | g6493.t1.exon2 | 17254367 | 17254458 |
| chr_2 | g6493 | g6493.t1 | cds | g6493.t1.CDS2 | 17254367 | 17254458 |
| chr_2 | g6493 | g6493.t1 | exon | g6493.t1.exon3 | 17254516 | 17255432 |
| chr_2 | g6493 | g6493.t1 | cds | g6493.t1.CDS3 | 17254516 | 17255432 |
| chr_2 | g6493 | g6493.t1 | exon | g6493.t1.exon4 | 17255494 | 17255725 |
| chr_2 | g6493 | g6493.t1 | cds | g6493.t1.CDS4 | 17255494 | 17255725 |
| chr_2 | g6493 | g6493.t1 | TTS | g6493.t1 | 17255882 | 17255882 |
Sequences
>g6493.t1 Gene=g6493 Length=1419
ATGAAACGCTACTGCGTGATTCTAATGATTGTCGTGAATGCTTTATTCAATAGCGTTCTC
ACACAAGATGAATATTGTTATTCAAATGATAATGATAAGAAACAAACTAAGCAATTTGGC
ACAAAAACACCATATGAGGTGCAGCGTGGGAATGAAAAACGTTATTTCAATGTTCCAAAA
TGTGAAGCAGTAAAGTTTTGGTTAATTTCAAGGCATGGAACACGAAATCCATCAGCAAAA
GGAATTGAACAGATGAAGAAATTATTTGATGTTCGTGATGGAATTTTAGAAAATTTCAAG
AGATTTGATAGAGATCGACATTTAAATCAATTGTGTAGTGAAGATCTTGAAATTTTAAAA
AATTGGCGTCTTGATAGAAACTTAACAGCTGAATATGAAAATCACTTAACTGTTCAAGGA
TGGAATGATTTAAAATATATGGCAATAGATTTTCAAAGAACATTTCAGAATGTTATTGAA
ACAAGATATTCAAGAGAGAAATTTAAATTTGGTTATACTGACACACAACGTGGTGAAGCA
AGTTTTAAGGCATTTGTTGAAGGACTTTTTGGTCCAAATGCTGAAGCAAGAATAAATATT
CCTGCTGAAGGAAACAACAGTATATTATTGAGGCCATATGAATCATGTTCGAAGTGGTTA
AAGGAAGAAGAAATGATTAAAGACCAAAATTCAGAATACTCTAAATTTATGCAAACTGAT
GTGTTTAAAAAGATGCTTGAAGAAGTTTCAATTAGACTTGGATATAAATACACATTGAAT
GCAAAGCAAATCGATAATATGTGGGATATGTGTAGATATGATCAAGCTTGGTATTTACAA
GAACCATCACCATGGTGTGTGGCTTTCACTCGTGAGCATGTAAACATTCTCGAATATCTT
GAAGATCTTAAATATTATTCAAAAGGTGGCTATGGTAATGAGATCAATTCGAAACTTATG
TGTGCTGCTGTTCAAGATATGTTGAGGACACTTCAAAGTGAACATTTGCCAAAAACTGTT
GCCTACTTTACTCATGCTTCTGCTATTCAACTATTTCTAACTGCCCTCGGCTATGCAAAA
GATAATGATGCATTAAGAGCAGACAATTATAATCAAATGAAAAACAGACAATTTCGAAGC
AGTGTACTGAGTCCATTCGCATCAAATTTAGCTGTAGTTAAATACGACTGTCCGGAGGAA
AGAGAAAGACATAAAGTTCAATTTTTCTTAAATGAACGTCCAATTGATTTTGAATGGTGT
AACATTGGATTGTGTGATCTACGAGAAGTACTAAATAGATATCGTCACTTTTTGGATGGC
GATTGTAAAAACATGTATTGTGGTGGAAATAATTCAAATTATTTGAAATTATCAACTTTA
ATGATCTGTTTTGTTACTTTAATTAAATTCATATTTTAG
>g6493.t1 Gene=g6493 Length=472
MKRYCVILMIVVNALFNSVLTQDEYCYSNDNDKKQTKQFGTKTPYEVQRGNEKRYFNVPK
CEAVKFWLISRHGTRNPSAKGIEQMKKLFDVRDGILENFKRFDRDRHLNQLCSEDLEILK
NWRLDRNLTAEYENHLTVQGWNDLKYMAIDFQRTFQNVIETRYSREKFKFGYTDTQRGEA
SFKAFVEGLFGPNAEARINIPAEGNNSILLRPYESCSKWLKEEEMIKDQNSEYSKFMQTD
VFKKMLEEVSIRLGYKYTLNAKQIDNMWDMCRYDQAWYLQEPSPWCVAFTREHVNILEYL
EDLKYYSKGGYGNEINSKLMCAAVQDMLRTLQSEHLPKTVAYFTHASAIQLFLTALGYAK
DNDALRADNYNQMKNRQFRSSVLSPFASNLAVVKYDCPEERERHKVQFFLNERPIDFEWC
NIGLCDLREVLNRYRHFLDGDCKNMYCGGNNSNYLKLSTLMICFVTLIKFIF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g6493.t1 | CDD | cd07061 | HP_HAP_like | 264 | 411 | 1.97622E-22 |
| 7 | g6493.t1 | Gene3D | G3DSA:3.40.50.1240 | - | 33 | 445 | 5.6E-80 |
| 2 | g6493.t1 | PANTHER | PTHR20963:SF48 | MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 | 8 | 454 | 8.1E-146 |
| 3 | g6493.t1 | PANTHER | PTHR20963 | MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED | 8 | 454 | 8.1E-146 |
| 15 | g6493.t1 | PIRSF | PIRSF000894 | Acid_Ptase | 1 | 452 | 8.7E-70 |
| 1 | g6493.t1 | Pfam | PF00328 | Histidine phosphatase superfamily (branch 2) | 68 | 411 | 6.2E-23 |
| 10 | g6493.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 21 | - |
| 11 | g6493.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 4 | - |
| 12 | g6493.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 5 | 16 | - |
| 14 | g6493.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 17 | 21 | - |
| 9 | g6493.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 22 | 453 | - |
| 13 | g6493.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 454 | 471 | - |
| 8 | g6493.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 472 | 472 | - |
| 4 | g6493.t1 | SUPERFAMILY | SSF53254 | Phosphoglycerate mutase-like | 32 | 460 | 5.38E-66 |
| 6 | g6493.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 21 | - |
| 17 | g6493.t1 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM | 1 | 21 | - |
| 5 | g6493.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 23 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016791 | phosphatase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K03103 (multiple inositol-polyphosphate phosphatase / 2,3-bisphosphoglycerate 3-phosphatase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
