General information for g6564.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Exportin-5.
Parent gene
- The parent gene g6564 is located on chr_2: 17652309..17656318 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6564 | g6564.t1 | TTS | g6564.t1 | 17652066 | 17652066 |
| chr_2 | g6564 | g6564.t1 | isoform | g6564.t1 | 17652309 | 17656318 |
| chr_2 | g6564 | g6564.t1 | exon | g6564.t1.exon1 | 17652309 | 17652731 |
| chr_2 | g6564 | g6564.t1 | cds | g6564.t1.CDS1 | 17652309 | 17652731 |
| chr_2 | g6564 | g6564.t1 | exon | g6564.t1.exon2 | 17652792 | 17652954 |
| chr_2 | g6564 | g6564.t1 | cds | g6564.t1.CDS2 | 17652792 | 17652954 |
| chr_2 | g6564 | g6564.t1 | exon | g6564.t1.exon3 | 17653044 | 17653419 |
| chr_2 | g6564 | g6564.t1 | cds | g6564.t1.CDS3 | 17653044 | 17653419 |
| chr_2 | g6564 | g6564.t1 | exon | g6564.t1.exon4 | 17653477 | 17656145 |
| chr_2 | g6564 | g6564.t1 | cds | g6564.t1.CDS4 | 17653477 | 17656145 |
| chr_2 | g6564 | g6564.t1 | exon | g6564.t1.exon5 | 17656203 | 17656318 |
| chr_2 | g6564 | g6564.t1 | cds | g6564.t1.CDS5 | 17656203 | 17656318 |
| chr_2 | g6564 | g6564.t1 | TSS | g6564.t1 | 17656653 | 17656653 |
Sequences
>g6564.t1 Gene=g6564 Length=3747
ATGGTCGATCCTTCACTTTCGGCATTAGCAAATGAACTCGCAACAGCGGTAGAAATTACA
TTAAATCCTCAAGCCTCTCAACAGGCACGAATGGAAGCTTATATTGCTTGTGAAAAATTT
AAAGAAATTTCTCCATTATGTGCTCAAGCTGGATTATTTCTCGTAACAAATCAGTTTTCT
GCAATAGTTAAACATTTTGGACTTCAACTCATGGAACATCAAGTAAAATTTAACTGGAAT
AAGATATCTCAAGATGAAAAAATTTTTATAAAGGATAATACAATGAAATTACTTTCAATT
GGAATTGGGCCAGCTGAAGATAAATCATTGATGCATATCAAAGATGCTCTTTCGCGAATT
GTTGTTGAAATGATTAAACGTGAATGGCCACAACAATGGCCAACATTGCTGACCGAATTA
TCAGCAGCTAGTGAGAAAGGATTATCTCAAACTGAATTGGTTGCTCTTGTATTTTTACGT
TTAGTTGAGGATGTGGCGCTTTTACAGACTATCGAATCTAATCAACGTAGAAAAGATATT
TATCAAGCTCTTACAGTAAATATGGGTGAAATTTTTGATTTCTTTCTCACTCAAATAGAA
AAAAATGTAAGCGACTATGTAACAACTAAAAATTTTGGAAGTTTACGTGTCGTTATTGTG
GTTTTAAATACATTGGCAAGTTTTGTTGAATGGGTCAATATAAGTCACATTATGGCTTCT
GATGGACGTTTATTGAAAATCATATGCTACTTATTAGAATTTCCTGATATTCAATTGGCA
GCTGCAGAATGTTTAAATCAAATAACTAATCGGAAAGGAGTTGCAAAAGATAAAAAACCA
TTGCTATATTTATTCAATGATGAGCCAATGCAGCACATTTTTCGCTCACTTGAATTAATG
ATGACAACTCAAACAGAAAGTTATTATCAATACTTAAAGAAACTTACACAAGCAATGTAT
GGTTTGACAAATCAATTAACATCACTTTGCGGAAAAGAATCTGATGTTCAAACACCACCA
CGCAACTTCTTTATGTTCCTTCAAATAATTTTAGCTTTTGCACGACATCCAAGTCTATCT
GTGACACATGGTGGTATTTTAATTTGGCTTCAATTAATTAAACATGATACAATTGCAAAG
GATCCAATTTTCGCCGATAGCATTCGTGTTATGATTGAAATTATTGGACCAAAATTAATC
AAACGTCCTTATCCAAAAGTTCGCAATTGTTTTACACCTAATTCAATTCCTTATACAACT
GAAGCATACACATGTCTTGATTTTGATAGTGAAGAAGATTATTTACAGTTCATACCGCGT
TTTCGTGTTGATCTTCTTGATATTTTTCGACAATCGACTCTTATTGCACCACTTTATACA
TTTTCATATTGTGAACACTGGTTAAATCGTCGTTTAGATTTGGCTAATTCAGAAAAATTG
ACTTCATGTAGCATCATGGATCCTGTATATCTTGAATGGGAAGCTGTTGTTGCTGTATTA
GATGGAGTTCTGAGTCGTATTTTATTGGTAACAGAACGTCCTTCAATCCTCAGTGGTCTC
GGACTTTTAAAAAAATGTTTGACTGTAAAAACTGATGAGCCATTAATTTATTCAGTTTTG
TTATCCTGCATTTCATCACTTTTCGTGTTCCTTAGTATGTCAGCATCTGGAAATATTGCT
GGCAATGGTGTACAATTGCTACCGCCAGTGTTGGAGAAAATATTTAGTGCCATTCTATTT
ACTTTACCAGTGTCAGAAGATCCACAATCTTTAAAATCTGCAGCTGTCAAAAATTTAAGA
CGTCATGCAGCTAGCTCAATTGTGAAAATTGCACTGAAATATCCTCTCCTCTTATTGCCA
ATTTTTGAGCAAATCAATACAACTGTGAAAAGTTTATGTGCTGAAAAAGATTCCAATTTA
TCAAATTGGGAAAAGCTATTACTACAAGAAGCTCTACTCATTATAAGCAATCATTTTTGT
GAGTTTGAACGTCAACAATTATTTGTTGCTGAAATAATTCGACCAGCAATTCAAATGTGG
CAAAATATTTCAATGCACTTGAAAATGCCAAATTTATTCATAGAATTTGTTGGTCTTTCA
AAATCAACTAGCAATCAAACAAATTTTAGAACTATTGATGAAGATGTTCATTATAAAAAT
CGTCAAACTGTTTTGTTAGCATTGAACACAGTTTTAGGTGTCATCAAACGTTGTCAATGC
CCTGATGATCCAGATAAGTCTGTTCGTGGTGGATTCGTTGTTGCAACAACTGACTCAGGA
AATCCAATCACACGAAATCCATCCGCTCCACACGTTATTCCACTGTTGCAACATATTCTA
GCACTAATGAGATGTTTAAATGAATTATACAATCCATCATCCCTTGCTCTCATCAGTAAT
ACATATAAAGGAGCTAATCAAATGTTAGAAAATGAAAAGAAGAACATTTTAGGTGTAGTC
TACTCAATACCCGATCCACTTGATCCAACTCAATTAACTAAAGTCAAAACACCATTTGAT
TACATGCAACAATTCCTATCGACAACATTTGATAATTGTTATCATTTGATGGGAGCTGCA
GGCTTAGCACTCGGTCGTGATTTCTATAGTCTCAGTGGACTTTCAACTGCACTTATTAAT
AGTTGCTTCAGTAGCATGGAACATATTCCAGATTTTCGATTGAGGACAATAATTCGTGTC
TTTTTACGTCCATTTATCTACTCGTGTCCAACAACTTATCACTCAGATGTGATTGTACCT
ATTTTTGCACACATTTCGCCATTCATGCTCTCTCGTTTGACCGCCAGATGGGATTATATA
TGTTCCCTTTATGAAAATGGTGCCTTGGGTGATGATACAAATAATGATGCTCAGGAAGTT
CTCGATGACATTCTAAATCGCACATTAACTCGAGAATATCTCGATGTGCTTAAAGTTGCT
CTTGTTGGAGGCACTGCTGGTACTACTGGAAATAATGATATTACATCAACTGAAATTGGA
AGTGGTTCAATGATGGATCAAGATGATTTTTCTATGGATGCTTTACCTCACATCACACGT
GCTGCTCAAGCTGCAATGCAATCAGACATTATTAGTGAATTGGGAAAGAAATTATTAGCA
AATCCGATTACATGCGAATCTGTTGTTTTTACTATTTTTAACTGCATCGCATGGAATGAT
AGCAATGCTAGTCTTAAAGCTTGTCTTCTTGCTGGTCCAGTAATACGTCATCTTTCAAAT
GAAGTAACACCAAATCTTGTTACAGTTATACTTACAAGAGTTCTTCAAGGTCTTCAATTA
CACGGACAACATGATGCTAATCAACCCTCACTTATAACATTAGGTGTGCAAGTTTATGAA
ATTGCACGACCATTACATCCATCAATCGTTTTGGGTATAATGCAACAAATACCGAATCTG
AATATAAATGATTTACAAAAATTAGATGAAAAGATTTTAAATTCAGGCCCATTAACAAAT
ACTACCAATCAAGGGACAATTGCTAGCACTATTAATACAACAACAAAATCAAACAAAATT
GATAAAACAAAGAAAGATCTCTTCAAAAAAATCACCTCTCATTTGGTGGGTCGGAATGTT
TTGGCTAGAATGTTCCGCAATCCTGCATCTATATCAGAATTGACTCCATTGAACAACAAC
AGTAATCAAAAAATTACAAATATATTGGAGTCTTCAAATGAGACTGGCCTTCAAATGCAA
AATTTATTCCGAGAAATTCCACGATAA
>g6564.t1 Gene=g6564 Length=1248
MVDPSLSALANELATAVEITLNPQASQQARMEAYIACEKFKEISPLCAQAGLFLVTNQFS
AIVKHFGLQLMEHQVKFNWNKISQDEKIFIKDNTMKLLSIGIGPAEDKSLMHIKDALSRI
VVEMIKREWPQQWPTLLTELSAASEKGLSQTELVALVFLRLVEDVALLQTIESNQRRKDI
YQALTVNMGEIFDFFLTQIEKNVSDYVTTKNFGSLRVVIVVLNTLASFVEWVNISHIMAS
DGRLLKIICYLLEFPDIQLAAAECLNQITNRKGVAKDKKPLLYLFNDEPMQHIFRSLELM
MTTQTESYYQYLKKLTQAMYGLTNQLTSLCGKESDVQTPPRNFFMFLQIILAFARHPSLS
VTHGGILIWLQLIKHDTIAKDPIFADSIRVMIEIIGPKLIKRPYPKVRNCFTPNSIPYTT
EAYTCLDFDSEEDYLQFIPRFRVDLLDIFRQSTLIAPLYTFSYCEHWLNRRLDLANSEKL
TSCSIMDPVYLEWEAVVAVLDGVLSRILLVTERPSILSGLGLLKKCLTVKTDEPLIYSVL
LSCISSLFVFLSMSASGNIAGNGVQLLPPVLEKIFSAILFTLPVSEDPQSLKSAAVKNLR
RHAASSIVKIALKYPLLLLPIFEQINTTVKSLCAEKDSNLSNWEKLLLQEALLIISNHFC
EFERQQLFVAEIIRPAIQMWQNISMHLKMPNLFIEFVGLSKSTSNQTNFRTIDEDVHYKN
RQTVLLALNTVLGVIKRCQCPDDPDKSVRGGFVVATTDSGNPITRNPSAPHVIPLLQHIL
ALMRCLNELYNPSSLALISNTYKGANQMLENEKKNILGVVYSIPDPLDPTQLTKVKTPFD
YMQQFLSTTFDNCYHLMGAAGLALGRDFYSLSGLSTALINSCFSSMEHIPDFRLRTIIRV
FLRPFIYSCPTTYHSDVIVPIFAHISPFMLSRLTARWDYICSLYENGALGDDTNNDAQEV
LDDILNRTLTREYLDVLKVALVGGTAGTTGNNDITSTEIGSGSMMDQDDFSMDALPHITR
AAQAAMQSDIISELGKKLLANPITCESVVFTIFNCIAWNDSNASLKACLLAGPVIRHLSN
EVTPNLVTVILTRVLQGLQLHGQHDANQPSLITLGVQVYEIARPLHPSIVLGIMQQIPNL
NINDLQKLDEKILNSGPLTNTTNQGTIASTINTTTKSNKIDKTKKDLFKKITSHLVGRNV
LARMFRNPASISELTPLNNNSNQKITNILESSNETGLQMQNLFREIPR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g6564.t1 | Gene3D | G3DSA:1.25.10.10 | - | 1 | 1155 | 0.0 |
| 3 | g6564.t1 | PANTHER | PTHR11223:SF3 | EXPORTIN-5 | 9 | 1185 | 7.6E-266 |
| 4 | g6564.t1 | PANTHER | PTHR11223 | EXPORTIN 1/5 | 9 | 1185 | 7.6E-266 |
| 1 | g6564.t1 | Pfam | PF03810 | Importin-beta N-terminal domain | 36 | 98 | 3.6E-5 |
| 2 | g6564.t1 | Pfam | PF08389 | Exportin 1-like protein | 112 | 265 | 1.5E-31 |
| 8 | g6564.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 534 | - |
| 10 | g6564.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 535 | 554 | - |
| 7 | g6564.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 555 | 565 | - |
| 11 | g6564.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 566 | 584 | - |
| 9 | g6564.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 585 | 1248 | - |
| 5 | g6564.t1 | SUPERFAMILY | SSF48371 | ARM repeat | 12 | 931 | 3.77E-48 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0031267 | small GTPase binding | MF |
| GO:0006886 | intracellular protein transport | BP |
| GO:0051168 | nuclear export | BP |
KEGG
Orthology
- This transcript has been annotated with K14289 (exportin-5)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
