General information for g6594.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein disabled.
Parent gene
- The parent gene g6594 is located on chr_2: 17741355..17746043 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6594 | g6594.t2 | isoform | g6594.t2 | 17741355 | 17745574 |
| chr_2 | g6594 | g6594.t2 | exon | g6594.t2.exon1 | 17741355 | 17741461 |
| chr_2 | g6594 | g6594.t2 | cds | g6594.t2.CDS1 | 17741355 | 17741461 |
| chr_2 | g6594 | g6594.t2 | exon | g6594.t2.exon2 | 17741547 | 17741687 |
| chr_2 | g6594 | g6594.t2 | cds | g6594.t2.CDS2 | 17741547 | 17741687 |
| chr_2 | g6594 | g6594.t2 | exon | g6594.t2.exon3 | 17741833 | 17744214 |
| chr_2 | g6594 | g6594.t2 | cds | g6594.t2.CDS3 | 17741833 | 17744214 |
| chr_2 | g6594 | g6594.t2 | exon | g6594.t2.exon4 | 17744269 | 17745133 |
| chr_2 | g6594 | g6594.t2 | cds | g6594.t2.CDS4 | 17744269 | 17745133 |
| chr_2 | g6594 | g6594.t2 | exon | g6594.t2.exon5 | 17745229 | 17745443 |
| chr_2 | g6594 | g6594.t2 | cds | g6594.t2.CDS5 | 17745229 | 17745443 |
| chr_2 | g6594 | g6594.t2 | exon | g6594.t2.exon6 | 17745544 | 17745574 |
| chr_2 | g6594 | g6594.t2 | cds | g6594.t2.CDS6 | 17745544 | 17745574 |
| chr_2 | g6594 | g6594.t2 | TSS | g6594.t2 | NA | NA |
| chr_2 | g6594 | g6594.t2 | TTS | g6594.t2 | NA | NA |
Sequences
>g6594.t2 Gene=g6594 Length=3741
ATGAATAATAGTGCAGATAAATGTAACAAATATCGAAATGAACCTGCAAGATTTTTTGGA
GATGGGGTTGTATTCAAGGCTAAACTTATTGGTATCTTGGAAGTTGGTGAAGCAAGAGGC
GATAGAATGTGTCAAGAAGCATTGCAGGACTTGAAAATCGCTATAAGAGCTGCAGGCGAA
CATAAACAACGCATAACTATTCATGTTACAATCGAAGGACTTCGACTTAGAGATGAAAAA
AGTGGAGAATCACTTTATCATCATCCGGTACATAAAATATCTTTTATAGCTCAAGATATG
ACTGATTCAAGAGCGTTTGGATACATCTTTGGTTCACCAGATTGCGGGCATAGATTTTTT
GGCATTAAAACGGATAAAGCAGCTAGTCAAGTTGTATTAGCTATGCGTGATTTATTTCAA
TGCGTTTTTGAGTTAAAGAAAAAGGAAATTGAGTTAGCCAAGCAACATATTCAAAATAGG
ATCACTGCACATGAACATCAGCAAATAAAAAGTTCTATACTAGAACATAAGAAAAGTACG
AGCTTACTAAATGAAGCAACAGCGATAACGAGACCGGCATCTAAAGCAGAAAAATCACCC
GAAGCGACAGCCAATTTAGTAGACTTAGAACAAGAATTGAGCTCGATTCAGCGTGGAATT
ACACAAATGGAAAGAATAACACCAAATGATGATGTTCCTTTAACTGCTATCACTTCAACT
AAAAATGTACTAGACGATGATCCCTTTGGCGACTCTTTCACAAGTTTCTCATCAACAACA
CCATTTAATATTTTGCCACCTCCAACAGCAGCTGCTAAACGTTCGATAATTTCCACTAAA
CAAGTAATTGATGAAGATCCTATTAGTTTAGGAGAATTGTCTTCTATAACTTATAAATCC
ACAACACCACCCATTTTACAATCTCAACCTCAGCAAGTATCAACATTAGATTCATGGCTA
CAATCTTCATCGTCCACATCAACAGTGCCATTCGTTGCTACTACTACTGCTCATGCATTT
AAAGAAAACGATACTATTATAAAAACTGATGAAAATTCCTCAATACGCAGTAATAGCAGT
AGCAGACAATTTCAAGAAGATGATTATGATAATCTAGATCCGCTTGGCAAGAAATCTTAT
GTAGATAAAAAATATTTTTTTCAAGACCTTAAAAATCCTCCTAAGAAGGTTTTAAAGGAT
TTGACATCAGAACAAGACAGTATTTTCGATGCACATTTCTCACCACTAAAAAGAAAAAAT
GAAGAGTCATTGTCTAGTTCACGTGCACATGAAGAAAACTCGCAAATAATTGATCCATTT
GAAGAGGAAGATTTTTCAAAAATTGTAATAGATCAATTAGAATCAACAACAACACCGGCA
ACAGCAACAGCAGTTAGTAAAAAATCAATAATATTACCAGACACAAAGATCAACTCTATA
ACTGAAATTAAATCAAAGAATGAAGAAAAATCACATGAGTATAAAGGATTTAATGTAGAC
TTGGATGCAGATTCATCTATTTATTCAACTGCAATATATACAGACTTAAAAAGGCAAAAT
TCTGATTCATCCTCGAAAAATGTTTTCTCTGTGGATTCGCTATCCAAAAAACTTCCTAAA
GCTAACTTATTTGGACAACGCAATGTAAAGAGAGATTCAAATGGAATTAACATGAGACGA
CTTCAGGAAAGTGATTCATTAAGTGAAGAAAATGAACCGGAATTACCTCCTCGATTGCCA
GATTCAGAACCACCTCCTTTGCCACCGAAAAATCAAATGAACCAAAAGGATTCAACAAAT
GAACTTCAATCTGATCGAAATCGTTATAGCAAAACTTCATCTTCAACGTCACGAGAATCA
GGTTCACGATACGATTATGCAAATAAATTTAAATCTCATTCAACTGATTCGCCACCTATT
CCTTTGCCAAGTCGAAAAATCAATAGAGCTGAAACTTCTAGATCTTCAAAAAGATCAAAT
GACGATGATGACTATTTGACTCCCAGTGTATCACTATCTTCACAAAACATTAACTCCACT
ATACCACAATTGCCGCCACCTCCTCCACAAAAAAACACCTCGAAACTTCGTGGAACACGA
AAATCTGAAACTGATCCGAAAAATCTTGATGCACCTACACCACCAGTTTCGGCCAAAGCA
GACTCTTCTGCAACTGCAATCATACCAGATATTACTCTAAGTCAATTATTAACATTAGGT
GTTGATGATTTGGCGCAAAAACTCAACGTACAACCTTCAAAATTAAATACAATGACACTT
GTCGAATTAACAACTTATTTATCTGAATTTATAGAAAACTCTAAACAATCAAATAATGCT
GTGCCAACAATGGCACCGCCTCCTCCTCCAATACCCATTCGTCCATCACTTGAAACTCCA
GTAGATTCACCAGTATTTAAAGTTAGTTTTGATGATGCCGTATTTGAAGCAAAATTTGAT
GATAATTTTGGTGAATTACAAGAACAATCGAAGCAACAACAACATGAAGAAACAAACTCA
TTTGTAGCTAATTTTGATAACTTTAATCAGGCGCCAGTATCTGTTATACCAACAGCAGAT
CGTTATGCTGTATTTCGGGAAATAATTGATCAAGAAATACAAAAACATCAATCATTTGAC
GGACATCAAGAATCAATTGAATCAAATAACTCAAACTCTTTGGAAGAAATTCAAGAAGGA
GGATCTTTTGATTTTACAAATGACCAAAATCAAAATGAATCACCACAAGAAAACCAATTT
CAGCAAAGTCCTATTCCCTATCAAACTCAATGTTCTTCAAAACTTGATAATAAAATAACT
GAAGCTTTATCTGGCGTTAAAGATCGATATGCTGCCTTACGTGAGCTTCGAAATATAGTT
TTGGTTGAAGACCTTTTTGATAAAAGCCCCAAACCACCATTAGCTTCTATTTCTGACTCA
AACTTGAGTGACGAAATTTGTGATGATGCATCAAGTTCAAATCAAGGATTTGCTTTATTT
CCAACAAGCGAAATAATTGAAGATAACTCTATGGAAAATATACCAACATATAATATATCG
TGGACAAATGATGAAGTTCCCACCGAAACTATAGAAAATATTGTTCAAGAAGAAGAGCAG
CAGCAACAACAGCAATCTTTTGAAGATGAAAGGTTAAGCAAAATTAATAATACTTTAAAC
GCTGGAAGCAATAAAGATGATTTGGAAATTGATGAATATATGAATAAGGCTATTTCCGAA
TTATCACTTGATCAGCGAATTTCACCTAATATACAAAACAAGTCTCCATCTATTAAAGCG
GAAGATGATGAGACTTTATTAAAACCATCATTGACAGCTTCAACAGAATGCAAAACATCA
GCTATGGTGTCCATAGAGAATAAATCATCATCACCTATAGCAAGTTCTCTTGTTATAAAA
ACAGAATCTTCCAATGAAGCAATGAATAATGAAAAAACTAATAGTGAAATAACAGAAAAA
GAAGAATCTAGAGAAAAAACAATTACTCCTGTTAAACCAATAGAATCTTCAGAATCGTGG
GCTGTATTTGAAGACACTCATATACAAACGAAAATGCCAGAAAAATCTAATATTGGTGTA
GCAAAAGCTGACTTTGAATCAGGTTCATCAGATGCCCATGGGAAGATGGACCAGAGCACA
GAAAAAGACATCAACATCCTCATTATCATCATTCATCTGAAAGATATTCTCGTCCGCAAG
CACCATCTCGACATAAAATGA
>g6594.t2 Gene=g6594 Length=1246
MNNSADKCNKYRNEPARFFGDGVVFKAKLIGILEVGEARGDRMCQEALQDLKIAIRAAGE
HKQRITIHVTIEGLRLRDEKSGESLYHHPVHKISFIAQDMTDSRAFGYIFGSPDCGHRFF
GIKTDKAASQVVLAMRDLFQCVFELKKKEIELAKQHIQNRITAHEHQQIKSSILEHKKST
SLLNEATAITRPASKAEKSPEATANLVDLEQELSSIQRGITQMERITPNDDVPLTAITST
KNVLDDDPFGDSFTSFSSTTPFNILPPPTAAAKRSIISTKQVIDEDPISLGELSSITYKS
TTPPILQSQPQQVSTLDSWLQSSSSTSTVPFVATTTAHAFKENDTIIKTDENSSIRSNSS
SRQFQEDDYDNLDPLGKKSYVDKKYFFQDLKNPPKKVLKDLTSEQDSIFDAHFSPLKRKN
EESLSSSRAHEENSQIIDPFEEEDFSKIVIDQLESTTTPATATAVSKKSIILPDTKINSI
TEIKSKNEEKSHEYKGFNVDLDADSSIYSTAIYTDLKRQNSDSSSKNVFSVDSLSKKLPK
ANLFGQRNVKRDSNGINMRRLQESDSLSEENEPELPPRLPDSEPPPLPPKNQMNQKDSTN
ELQSDRNRYSKTSSSTSRESGSRYDYANKFKSHSTDSPPIPLPSRKINRAETSRSSKRSN
DDDDYLTPSVSLSSQNINSTIPQLPPPPPQKNTSKLRGTRKSETDPKNLDAPTPPVSAKA
DSSATAIIPDITLSQLLTLGVDDLAQKLNVQPSKLNTMTLVELTTYLSEFIENSKQSNNA
VPTMAPPPPPIPIRPSLETPVDSPVFKVSFDDAVFEAKFDDNFGELQEQSKQQQHEETNS
FVANFDNFNQAPVSVIPTADRYAVFREIIDQEIQKHQSFDGHQESIESNNSNSLEEIQEG
GSFDFTNDQNQNESPQENQFQQSPIPYQTQCSSKLDNKITEALSGVKDRYAALRELRNIV
LVEDLFDKSPKPPLASISDSNLSDEICDDASSSNQGFALFPTSEIIEDNSMENIPTYNIS
WTNDEVPTETIENIVQEEEQQQQQQSFEDERLSKINNTLNAGSNKDDLEIDEYMNKAISE
LSLDQRISPNIQNKSPSIKAEDDETLLKPSLTASTECKTSAMVSIENKSSSPIASSLVIK
TESSNEAMNNEKTNSEITEKEESREKTITPVKPIESSESWAVFEDTHIQTKMPEKSNIGV
AKADFESGSSDAHGKMDQSTEKDINILIIIIHLKDILVRKHHLDIK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g6594.t2 | CDD | cd01215 | PTB_Dab | 9 | 155 | 1.62676E-83 |
| 8 | g6594.t2 | Coils | Coil | Coil | 147 | 167 | - |
| 9 | g6594.t2 | Coils | Coil | Coil | 206 | 226 | - |
| 7 | g6594.t2 | Gene3D | G3DSA:2.30.29.30 | - | 8 | 163 | 1.5E-36 |
| 15 | g6594.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 350 | 371 | - |
| 18 | g6594.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 350 | 365 | - |
| 19 | g6594.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 544 | 721 | - |
| 14 | g6594.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 553 | 577 | - |
| 13 | g6594.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 592 | 623 | - |
| 16 | g6594.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 650 | 664 | - |
| 17 | g6594.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 665 | 680 | - |
| 12 | g6594.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1143 | 1166 | - |
| 3 | g6594.t2 | PANTHER | PTHR11232 | PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER | 10 | 256 | 4.4E-146 |
| 5 | g6594.t2 | PANTHER | PTHR11232:SF47 | PROTEIN DISABLED | 10 | 256 | 4.4E-146 |
| 2 | g6594.t2 | PANTHER | PTHR11232 | PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER | 372 | 404 | 4.4E-146 |
| 4 | g6594.t2 | PANTHER | PTHR11232:SF47 | PROTEIN DISABLED | 372 | 404 | 4.4E-146 |
| 1 | g6594.t2 | Pfam | PF00640 | Phosphotyrosine interaction domain (PTB/PID) | 25 | 145 | 1.0E-6 |
| 20 | g6594.t2 | ProSiteProfiles | PS01179 | Phosphotyrosine interaction domain (PID) profile. | 20 | 151 | 30.952 |
| 11 | g6594.t2 | SMART | SM00462 | PTB_9 | 20 | 152 | 6.9E-35 |
| 6 | g6594.t2 | SUPERFAMILY | SSF50729 | PH domain-like | 9 | 150 | 4.78E-35 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0032502 | developmental process | BP |
KEGG
Orthology
- This transcript has been annotated with K12475 (disabled homolog 2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
