General information for g6635.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phosphoglucomutase-2.
Parent gene
- The parent gene g6635 is located on chr_2: 17893964..17900832 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6635 | g6635.t1 | TTS | g6635.t1 | 17890390 | 17890390 |
| chr_2 | g6635 | g6635.t1 | isoform | g6635.t1 | 17890465 | 17894833 |
| chr_2 | g6635 | g6635.t1 | exon | g6635.t1.exon1 | 17890465 | 17890567 |
| chr_2 | g6635 | g6635.t1 | cds | g6635.t1.CDS1 | 17890465 | 17890567 |
| chr_2 | g6635 | g6635.t1 | exon | g6635.t1.exon2 | 17890625 | 17891773 |
| chr_2 | g6635 | g6635.t1 | cds | g6635.t1.CDS2 | 17890625 | 17891773 |
| chr_2 | g6635 | g6635.t1 | exon | g6635.t1.exon3 | 17893984 | 17894229 |
| chr_2 | g6635 | g6635.t1 | cds | g6635.t1.CDS3 | 17893984 | 17894229 |
| chr_2 | g6635 | g6635.t1 | exon | g6635.t1.exon4 | 17894287 | 17894402 |
| chr_2 | g6635 | g6635.t1 | cds | g6635.t1.CDS4 | 17894287 | 17894402 |
| chr_2 | g6635 | g6635.t1 | exon | g6635.t1.exon5 | 17894457 | 17894603 |
| chr_2 | g6635 | g6635.t1 | cds | g6635.t1.CDS5 | 17894457 | 17894603 |
| chr_2 | g6635 | g6635.t1 | exon | g6635.t1.exon6 | 17894747 | 17894833 |
| chr_2 | g6635 | g6635.t1 | cds | g6635.t1.CDS6 | 17894747 | 17894833 |
| chr_2 | g6635 | g6635.t1 | TSS | g6635.t1 | 17894902 | 17894902 |
Sequences
>g6635.t1 Gene=g6635 Length=1848
ATGTCATCTTTAGAAAAAGATATTAAAATAAATTCAGGAAATGTCGAACTAGATGAGAAA
ATTCAAGAGTGGATTGATTGGGATAAGAATGAAAAGACACTTGATGAGATAAAATCTCTA
GTACTATTGGGAGATTATGAAACATTAAAAAAGCGACTTTTATGTCGTATGGCATTTGGA
ACAGCAGGCCTTCGTGGAAAAATGCAAGCAGGCTTCTCATTTATGAATGATTTGGTTATT
GTACAAACTGGACAAGGCTTAGTAACATACATCAAAAAATGTTTTCCGAATAAAGTAGAT
CAGCAGCGTGGAGTTGTTATAAGCTATGATGGACGATACAACAGTAGACGATTTGCTGAG
CTTACCGCCACAATATTCATCAATGAAAATATACCAGTTTATTTTTACAGTAAACTTACT
GCTACACCATTTGTTCCATTTGCAGTTTATCACAAAAAGGCTTTATGTGGTATTATGGTT
ACAGCATCACATAATCCTAAAGAAGACAATGGCTATAAAGTTTATTGGGAAAATTCTGCT
CAAATAATCTCACCACATGATAAAAATATACAAAACAGCATTTTGAAGAATTTAAATCCA
TTGCCATCATCTTGGAAAACTGAAGAGGCAATGAAATCATCATTATTGCATGATCCATAT
GATGAAATGTTTAAATTATACTTTGATAAACTTCAAGCAACAATCCCTCCGAAATTTTAT
AAAATTAATGAAGAAGCACAACTTAAAATTGTTTATACCGCTATGCATGGTGTTGGATAT
CCATTTGTTCAAAAAGCTTATGAAATTTCAAACCTTAAGCCAGTACATGCTGTTATTGAA
CAACGTGATCCAGATCCAGAATTTCCAACCGTAAAATTCCCAAATCCTGAAGAGGGAAAA
TCATGTCTAGTTTTATCAATGAAACTAGCTGATGAAGTTGGTAGTGATCTGATAATTGCA
AATGATCCAGATGCCGATCGTCTGGCTGTTGCCGAAAGAGATTCGCGAACCAAAGAATGG
AAAGTGTTTAATGGAAATGAAATTGGATCGCTTCTTGGATGGTGGTCGGTCAAGTGTTTT
AAAGAAGCTCATCCAAATGTAGATGATATGAAAAATTGCTATCTTCTTGCAAGTACTGTT
AGTTCAAAGATGCTTAAATCTATGGGAAAAAAGGAAGGATTTAATTTTGAGGAGACATTA
ACCGGTTTTAAATATATGGGAAATCGAAGTGTTGAATTTATGGAAAAAGGAAATCAAGTA
CTATTTGCTTTCGAGGAAGCAATCGGATTCATGGTATCTTCAAACGTTTTAGATAAAGAC
GGAGTAAGTGCTGCTGCTCATTTAGGAACTATGGCATCTTATATGAAACTAAAAGAAAAT
AAAACTTTATGTGAGACATTAGAGTATCTTTATAAAATGTACGGCTATCATTATTCATTA
AATAGTTATTTCTTATGTTATGAACCTGAAAAAATCATAAAAATATTTGAGCGTATAAGA
AACTGGAAAGGCGAAAAAGATTCTTATCCTTCATCTATTGGAAATTATAAAATTGATAGT
ATTCGTGACTTGACAGCTGGAATCGACACTTCTCAACCTAATAGAAAACCGTTACTTCCT
TCAAGCAAAAGTTCTCAAATGATTACGTTTACATTTGAAAATGATACAGTTTTGACATTA
CGTACAAGTGGAACGGAACCAAAAATAAAATATTATTCTGAATATTGTGCAAAACCTGAT
GAAAACAATTGGAAGGAGATTCAAGATAAACTGAAGGACATAGTTGATAAGACTGTCAAT
GAACTGCTTCAACCTACTGAGAATGGACTTATTCAAAAATCTGACTAA
>g6635.t1 Gene=g6635 Length=615
MSSLEKDIKINSGNVELDEKIQEWIDWDKNEKTLDEIKSLVLLGDYETLKKRLLCRMAFG
TAGLRGKMQAGFSFMNDLVIVQTGQGLVTYIKKCFPNKVDQQRGVVISYDGRYNSRRFAE
LTATIFINENIPVYFYSKLTATPFVPFAVYHKKALCGIMVTASHNPKEDNGYKVYWENSA
QIISPHDKNIQNSILKNLNPLPSSWKTEEAMKSSLLHDPYDEMFKLYFDKLQATIPPKFY
KINEEAQLKIVYTAMHGVGYPFVQKAYEISNLKPVHAVIEQRDPDPEFPTVKFPNPEEGK
SCLVLSMKLADEVGSDLIIANDPDADRLAVAERDSRTKEWKVFNGNEIGSLLGWWSVKCF
KEAHPNVDDMKNCYLLASTVSSKMLKSMGKKEGFNFEETLTGFKYMGNRSVEFMEKGNQV
LFAFEEAIGFMVSSNVLDKDGVSAAAHLGTMASYMKLKENKTLCETLEYLYKMYGYHYSL
NSYFLCYEPEKIIKIFERIRNWKGEKDSYPSSIGNYKIDSIRDLTAGIDTSQPNRKPLLP
SSKSSQMITFTFENDTVLTLRTSGTEPKIKYYSEYCAKPDENNWKEIQDKLKDIVDKTVN
ELLQPTENGLIQKSD
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 17 | g6635.t1 | CDD | cd05799 | PGM2 | 56 | 593 | 0.0 |
| 15 | g6635.t1 | Gene3D | G3DSA:3.40.120.10 | - | 48 | 209 | 6.7E-47 |
| 14 | g6635.t1 | Gene3D | G3DSA:3.40.120.10 | - | 224 | 342 | 3.7E-21 |
| 16 | g6635.t1 | Gene3D | G3DSA:3.40.120.10 | - | 343 | 475 | 1.2E-27 |
| 13 | g6635.t1 | Gene3D | G3DSA:3.30.310.50 | Major birch pollen allergen Bet v 1 | 503 | 597 | 4.7E-5 |
| 4 | g6635.t1 | PANTHER | PTHR45745 | PHOSPHOMANNOMUTASE 45A | 15 | 604 | 2.5E-237 |
| 7 | g6635.t1 | PRINTS | PR00509 | Phosphoglucomutase/phosphomannomutase family signature | 156 | 170 | 3.5E-8 |
| 5 | g6635.t1 | PRINTS | PR00509 | Phosphoglucomutase/phosphomannomutase family signature | 247 | 266 | 3.5E-8 |
| 6 | g6635.t1 | PRINTS | PR00509 | Phosphoglucomutase/phosphomannomutase family signature | 315 | 330 | 3.5E-8 |
| 3 | g6635.t1 | Pfam | PF02878 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I | 57 | 197 | 6.9E-37 |
| 2 | g6635.t1 | Pfam | PF02879 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II | 227 | 332 | 6.8E-24 |
| 1 | g6635.t1 | Pfam | PF02880 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III | 374 | 473 | 1.2E-11 |
| 12 | g6635.t1 | ProSitePatterns | PS00710 | Phosphoglucomutase and phosphomannomutase phosphoserine signature. | 157 | 166 | - |
| 9 | g6635.t1 | SUPERFAMILY | SSF53738 | Phosphoglucomutase, first 3 domains | 45 | 254 | 2.71E-43 |
| 10 | g6635.t1 | SUPERFAMILY | SSF53738 | Phosphoglucomutase, first 3 domains | 225 | 334 | 9.81E-20 |
| 11 | g6635.t1 | SUPERFAMILY | SSF53738 | Phosphoglucomutase, first 3 domains | 323 | 477 | 1.82E-24 |
| 8 | g6635.t1 | SUPERFAMILY | SSF55957 | Phosphoglucomutase, C-terminal domain | 485 | 603 | 2.75E-11 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0000287 | magnesium ion binding | MF |
| GO:0005975 | carbohydrate metabolic process | BP |
| GO:0071704 | organic substance metabolic process | BP |
| GO:0016868 | intramolecular transferase activity, phosphotransferases | MF |
KEGG
Orthology
- This transcript has been annotated with K01835 (phosphoglucomutase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
