General information for g6653.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative UDP-glucuronosyltransferase 2B31.
Parent gene
- The parent gene g6653 is located on chr_2: 17951237..17953125 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6653 | g6653.t1 | isoform | g6653.t1 | 17951237 | 17953125 |
| chr_2 | g6653 | g6653.t1 | exon | g6653.t1.exon1 | 17951237 | 17951330 |
| chr_2 | g6653 | g6653.t1 | cds | g6653.t1.CDS1 | 17951237 | 17951330 |
| chr_2 | g6653 | g6653.t1 | exon | g6653.t1.exon2 | 17951391 | 17951557 |
| chr_2 | g6653 | g6653.t1 | cds | g6653.t1.CDS2 | 17951391 | 17951557 |
| chr_2 | g6653 | g6653.t1 | exon | g6653.t1.exon3 | 17951620 | 17951843 |
| chr_2 | g6653 | g6653.t1 | cds | g6653.t1.CDS3 | 17951620 | 17951843 |
| chr_2 | g6653 | g6653.t1 | exon | g6653.t1.exon4 | 17951907 | 17952258 |
| chr_2 | g6653 | g6653.t1 | cds | g6653.t1.CDS4 | 17951907 | 17952258 |
| chr_2 | g6653 | g6653.t1 | exon | g6653.t1.exon5 | 17952313 | 17952535 |
| chr_2 | g6653 | g6653.t1 | cds | g6653.t1.CDS5 | 17952313 | 17952535 |
| chr_2 | g6653 | g6653.t1 | exon | g6653.t1.exon6 | 17952596 | 17953125 |
| chr_2 | g6653 | g6653.t1 | cds | g6653.t1.CDS6 | 17952596 | 17953125 |
| chr_2 | g6653 | g6653.t1 | TTS | g6653.t1 | 17953811 | 17953811 |
| chr_2 | g6653 | g6653.t1 | TSS | g6653.t1 | NA | NA |
Sequences
>g6653.t1 Gene=g6653 Length=1590
ATGAAATTTTTATTAAATTTCATAATAATATTGTGTATTTTACTTGCACTACCTGTAAAT
TGTCATCGAATTTTGGGCCTATTTCCACACCCAGGACATTCACATTTTCAATTTTTTCAT
CCTATTATGAAAGCACTTGCTGAGAGAGGTCATGAGGTGACGGTTGTAAGTGAATTTCCT
AATAAGGAACCACTTGAGAATTACCACGATGAAATTTTAACAAATCAAGGAACTGGATTA
TTAAACTTTGTTTCTCTTGATAATTTCAAAACACAGTCAGTTTTTCAACATTTTTTTGAG
TTTTTTATGCTTCGTGAATGGGGAAAGGAAGCATGCGCTAAGGCATTAAACTCGTCTGCT
ATTAAAAATGTTCTTAACAAAGGTCGTCGTGAACCGTTTGATTTGATAATTGTTGAATTG
TTTAATACTGATTGTATGATGGGAGTCGCTCACAAATTGAAAGCGCCAGTGATTGGATTG
AGCAGTTGTAACATTTTACCTTGGCATTTCACACAACTTGGATTGCCCTATGAAACCAAT
TTCTATCCAGTTACATTTTTAGGAGCTTCTGATAAAATGTCATATACACAGCGCATTTCT
AATTGGTTTGCTTTTGTTTACATGAATATCATGTACAAAATTTTTAGTCAAAATGATGCT
AATAAATTACTGCGTCAACGGTTCGGTGATGATTTTCCAGATGTTTCTGATCTTACGAAA
AAAGTGTCAATGATGTTTGTTAATCAACATTATTCACTTAGTGGAGCAAAACATATTTCA
CCAAACATAATTGAACTTGGCGGCATTCACATTGAGAAACCAAATTCAATCGATTCGAAA
TTACAAAATCTCCTTGATAATGCTAAAAATGGTGTTATATATATAAGTTGGGGATCAATG
GTGAAAGCAGATTCTCTTAGTGAACTCAAACGAGAAGGGATTTTGCGTGCATTAGGCAAA
TTTAAGCAACTTGTGTTATGGAAATATGAAAATGATACATTGCCAAACCAACCTTCTAAT
GTCATCATAAGAAAATGGATGCCACAACGCGAGATTTTATGTCATCCAAATACACGAGTA
TTTTTAACACACGGAGGCTTAATGGGAAGTTCTGAGGCAGCTTATTGTGGTGTACCAGTA
GTTGCAACGCCTTTTTATGGAGATCAATTCTTAAATGTAGCTGCACTTGAGAATCGTGCA
ATGGGAGTAATTTTAAAATATAATGATATTAACGAACAAACAGTGCATCATTCATTACGC
CGAGTTTTAGATGCCAAATATCGAGAAAATGCAAAGAAAGTTCAATATTCATTTAAACAT
AGACCTATGCCACCTATTGAAACTGCTGTGTTTTGGTCAGAATATGTTATTGCTAGTGGT
GGTGCTCATCTTGTTCAACCATATACAGTTTATGCAAATTGGTTTATTTACAGTGGTTTA
GATATTATTCTTACCATTCTAAGTGCAATATTATTTTTTATTGGAAGTTGGATATACATT
ATTCGTAAATGTTTTTTTAGAAACAAAAAATTGGTTGATTCTAAAAAATCTCATCAAGTA
TCAAATGATTTGTTAAAAAAGAAAAATTAA
>g6653.t1 Gene=g6653 Length=529
MKFLLNFIIILCILLALPVNCHRILGLFPHPGHSHFQFFHPIMKALAERGHEVTVVSEFP
NKEPLENYHDEILTNQGTGLLNFVSLDNFKTQSVFQHFFEFFMLREWGKEACAKALNSSA
IKNVLNKGRREPFDLIIVELFNTDCMMGVAHKLKAPVIGLSSCNILPWHFTQLGLPYETN
FYPVTFLGASDKMSYTQRISNWFAFVYMNIMYKIFSQNDANKLLRQRFGDDFPDVSDLTK
KVSMMFVNQHYSLSGAKHISPNIIELGGIHIEKPNSIDSKLQNLLDNAKNGVIYISWGSM
VKADSLSELKREGILRALGKFKQLVLWKYENDTLPNQPSNVIIRKWMPQREILCHPNTRV
FLTHGGLMGSSEAAYCGVPVVATPFYGDQFLNVAALENRAMGVILKYNDINEQTVHHSLR
RVLDAKYRENAKKVQYSFKHRPMPPIETAVFWSEYVIASGGAHLVQPYTVYANWFIYSGL
DIILTILSAILFFIGSWIYIIRKCFFRNKKLVDSKKSHQVSNDLLKKKN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g6653.t1 | CDD | cd03784 | GT1_Gtf-like | 23 | 434 | 4.91365E-69 |
| 6 | g6653.t1 | Gene3D | G3DSA:3.40.50.2000 | Glycogen Phosphorylase B; | 24 | 223 | 2.6E-12 |
| 7 | g6653.t1 | Gene3D | G3DSA:3.40.50.2000 | Glycogen Phosphorylase B; | 272 | 439 | 2.7E-43 |
| 2 | g6653.t1 | PANTHER | PTHR48043 | EG:EG0003.4 PROTEIN-RELATED | 13 | 493 | 2.8E-201 |
| 3 | g6653.t1 | PANTHER | PTHR48043:SF114 | DOROTHY, ISOFORM A-RELATED | 13 | 493 | 2.8E-201 |
| 1 | g6653.t1 | Pfam | PF00201 | UDP-glucoronosyl and UDP-glucosyl transferase | 34 | 516 | 1.9E-66 |
| 10 | g6653.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 21 | - |
| 11 | g6653.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 6 | - |
| 12 | g6653.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 7 | 17 | - |
| 14 | g6653.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 18 | 21 | - |
| 9 | g6653.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 22 | 473 | - |
| 13 | g6653.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 474 | 500 | - |
| 8 | g6653.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 501 | 529 | - |
| 18 | g6653.t1 | ProSitePatterns | PS00375 | UDP-glycosyltransferases signature. | 346 | 389 | - |
| 4 | g6653.t1 | SUPERFAMILY | SSF53756 | UDP-Glycosyltransferase/glycogen phosphorylase | 22 | 462 | 4.45E-102 |
| 5 | g6653.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 21 | - |
| 16 | g6653.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 7 | 29 | - |
| 17 | g6653.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 479 | 501 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008194 | UDP-glycosyltransferase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00699 (glucuronosyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
