General information for g6698.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Fasciclin-2.
Parent gene
- The parent gene g6698 is located on chr_2: 18103511..18104056 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6698 | g6698.t1 | TSS | g6698.t1 | 18100890 | 18100890 |
| chr_2 | g6698 | g6698.t1 | isoform | g6698.t1 | 18101116 | 18104056 |
| chr_2 | g6698 | g6698.t1 | exon | g6698.t1.exon1 | 18101116 | 18101167 |
| chr_2 | g6698 | g6698.t1 | cds | g6698.t1.CDS1 | 18101116 | 18101167 |
| chr_2 | g6698 | g6698.t1 | exon | g6698.t1.exon2 | 18101229 | 18101406 |
| chr_2 | g6698 | g6698.t1 | cds | g6698.t1.CDS2 | 18101229 | 18101406 |
| chr_2 | g6698 | g6698.t1 | exon | g6698.t1.exon3 | 18101475 | 18102109 |
| chr_2 | g6698 | g6698.t1 | cds | g6698.t1.CDS3 | 18101475 | 18102109 |
| chr_2 | g6698 | g6698.t1 | exon | g6698.t1.exon4 | 18102181 | 18102765 |
| chr_2 | g6698 | g6698.t1 | cds | g6698.t1.CDS4 | 18102181 | 18102765 |
| chr_2 | g6698 | g6698.t1 | exon | g6698.t1.exon5 | 18102824 | 18103148 |
| chr_2 | g6698 | g6698.t1 | cds | g6698.t1.CDS5 | 18102824 | 18103148 |
| chr_2 | g6698 | g6698.t1 | exon | g6698.t1.exon6 | 18103206 | 18103440 |
| chr_2 | g6698 | g6698.t1 | cds | g6698.t1.CDS6 | 18103206 | 18103440 |
| chr_2 | g6698 | g6698.t1 | exon | g6698.t1.exon7 | 18103505 | 18103890 |
| chr_2 | g6698 | g6698.t1 | cds | g6698.t1.CDS7 | 18103505 | 18103890 |
| chr_2 | g6698 | g6698.t1 | exon | g6698.t1.exon8 | 18103957 | 18104056 |
| chr_2 | g6698 | g6698.t1 | cds | g6698.t1.CDS8 | 18103957 | 18104056 |
| chr_2 | g6698 | g6698.t1 | TTS | g6698.t1 | 18104839 | 18104839 |
Sequences
>g6698.t1 Gene=g6698 Length=2496
ATGAAAAAATTTGCCTTATTAATCATATTATATTTATTCAATTTGTTTTATGATTGTCAA
AGTCAAAATATAAAACAACCGCGCCTAGAAATTCTTCCAAATCAACCAGTGCAGAGACGT
GCAATTAATCGACCTCTTGTATTAACATGCAGTCCTAACGTTGAACAAAAAGATTTGATA
ACTGACTTAAAATGGAAAGACAGTTCTAACCAAACTATAAATCCTAAACAATATGGATCT
CAACCAATTATATATACAGAAACATTAAATATTAACCAATTAATGCTTGTTATAACTTCT
TTGACCGAAGCATTGGCAGGTTATTATTACTGTTCAGCTTCTTACGCAAATTCAGAATAT
ATTGAAGAAAAAGTAAAGATCGAAACATATGTTGCAATCACCTATAAAGACGCCAATATA
TATCAAACGACCAACTTAAACACTGATTATGTTATACGATGTATCGTTACTGCAAATCCT
CCACCAAGTGTTGATTGGCTTCGTAATGGAGATCAGATAAAATCATCAGAAAAATTCATA
ATCAAGCATGATGGTTTATTAGTGAAAAATGTTCAAGAATCAGATGATGGTATATATACA
TGCAGAGCTGCCGTTATTCAGACTGGAGAATTGATGGAAAGAAATATACGGTTAGAAGTT
CAAATTCAACCAACTATAGAAATTTTAAACGATGTTTATGAGGCAATTGAGGGCGAAGAA
TTTTCTGCTAAATGTGTAGCATCTGGAAAACCTCCGCCTTTGGTTCAATGGATCAAAGAT
CAAAGAGATATGTCACTTGCAGACCGTTTTTCAGTTGTTCCACATAATGGACAACTTAGT
ATAACAAGAGTTGAAGCTGAACATGATAGAGGTATTTATAAATGTCTAGCAAAAAACCCA
GCTGGAATTGCTGAAAAAGAAACTAGATTGAATGTTGTAATGAAACCCAAAATTTTTGAA
CTCAAGAATATTACTGTTCCAATAAATAATGAAACAATGCTTATTTGCAAGAGCAAAGGA
TGGCCCATACCATTTGTAACATTTAGAAAATGGGGTTCAAAAGAAGAACTTCGATTAGGT
CATCAAGAGAACGATGATCGTATTATTTTAGAACAAACAGTTGACAATGAAATGGGCGAA
TCAACAGGAATTTTAGTTATTTCGAGCGTAATCAGAGCAGATGATGGGTTGTATCAATGT
GTTGCCAGAAATAAAGGGGGAACAGCTTTTGAAGTAGGCCATATAACAGTCGAGTATCCA
CCAAACTTTGATCACATGAAGGATTTACCACCCGTATTTTCTTGGGAAGAAAGAGTGGCA
AATTTAAGTTGTATGGCTATGGCATTACCAAACGCAACAATAGAGTGGCGCTGGAATGAA
CGTTTAATACGAGAAATGCAAGATAAATTTTTACAAATTGTTGAAGATGGACCTAGAAGT
GACTTGATAGTTAGACCTGTTGAGCGCAGATATTATTCTGCATATAAATGTATAGCTGTA
AATAAAATTGGAAGAGCTGAACACATTATGGAATTAAGAGAAGCACACTTGCCTTCAGCT
GTAGCACAAGCTAAGCCTATAGAAGTTACAGCAACAACAATAACATTTGATATAATAGGG
CCACCATTTGAAATTGGTATGCCTATAAAAGCTTATACTGCACAATATAAGGAAGAAAGG
AATCCTGATTGGTTATATGCATTCAATCGAACGTGGTCCACAGACACACCCTATGTCATT
GAAGGATTAAGACCGCAGACAATGTATACCTTTAGATTTGCAGCAAGAAATGATGTGGGT
CTTGGTCAATGGAGCGCTATTAAAGTTCAAGCAACTCCTTCTCGATCAACACCCGAAACG
CCAAAAATTTTAAATCAATTTGCACAAGAAGTTGAAGATGGAGAATTACCTATAATAACT
TCATTGTTTGCAGACAGATTTGAACTTATATGGAACCGACCTCCTGATAATGGAGAACCA
ATCGATTTTTATGCTATAAAATATTGTCCAGGAAACAAAATTAACAATAATTGGAATGAA
ATAGGAAGACTATGCAATGAACAAAGTTATATTGCATACACATTTTCTAATTTTGTGCTT
AAGAGATTAATGCCTGATACATACTATAAGATAGAACTAAGAGCTCATAACGCTATAGGT
TTCTCATCTCCAGCTTATGCATACCTAAAAACAGCTAGAGGAGCAGAATTAAAAGGGGAT
ATTGAAAGAATAGAAGAAGAGCATTTTCATTTATCATCCATTTCAATCGTATTGATTGCA
ATTTTAGCAATTATCTTAATATTACTTTTAATTGACCTCACTTTCTGTATTACAAAAGAT
TTAGGTATCTTTGCATTAATTTTTTCGCGAAAATCCCATACTACAAATCAAAGAAGACAA
AATGAAAAAAGAGAGCTAATAACAGTTTTTGGACAACAAAGACAACGTCAGCAACAGCAT
TCAAATGATGCAATTGGAAAGAATTCGTCCGTGTAG
>g6698.t1 Gene=g6698 Length=831
MKKFALLIILYLFNLFYDCQSQNIKQPRLEILPNQPVQRRAINRPLVLTCSPNVEQKDLI
TDLKWKDSSNQTINPKQYGSQPIIYTETLNINQLMLVITSLTEALAGYYYCSASYANSEY
IEEKVKIETYVAITYKDANIYQTTNLNTDYVIRCIVTANPPPSVDWLRNGDQIKSSEKFI
IKHDGLLVKNVQESDDGIYTCRAAVIQTGELMERNIRLEVQIQPTIEILNDVYEAIEGEE
FSAKCVASGKPPPLVQWIKDQRDMSLADRFSVVPHNGQLSITRVEAEHDRGIYKCLAKNP
AGIAEKETRLNVVMKPKIFELKNITVPINNETMLICKSKGWPIPFVTFRKWGSKEELRLG
HQENDDRIILEQTVDNEMGESTGILVISSVIRADDGLYQCVARNKGGTAFEVGHITVEYP
PNFDHMKDLPPVFSWEERVANLSCMAMALPNATIEWRWNERLIREMQDKFLQIVEDGPRS
DLIVRPVERRYYSAYKCIAVNKIGRAEHIMELREAHLPSAVAQAKPIEVTATTITFDIIG
PPFEIGMPIKAYTAQYKEERNPDWLYAFNRTWSTDTPYVIEGLRPQTMYTFRFAARNDVG
LGQWSAIKVQATPSRSTPETPKILNQFAQEVEDGELPIITSLFADRFELIWNRPPDNGEP
IDFYAIKYCPGNKINNNWNEIGRLCNEQSYIAYTFSNFVLKRLMPDTYYKIELRAHNAIG
FSSPAYAYLKTARGAELKGDIERIEEEHFHLSSISIVLIAILAIILILLLIDLTFCITKD
LGIFALIFSRKSHTTNQRRQNEKRELITVFGQQRQRQQQHSNDAIGKNSSV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 31 | g6698.t1 | CDD | cd00096 | Ig | 151 | 203 | 1.57032E-13 |
| 32 | g6698.t1 | CDD | cd00096 | Ig | 244 | 309 | 3.86458E-12 |
| 34 | g6698.t1 | CDD | cd00096 | Ig | 334 | 409 | 1.26925E-8 |
| 33 | g6698.t1 | CDD | cd00096 | Ig | 440 | 511 | 1.16089E-7 |
| 35 | g6698.t1 | CDD | cd00063 | FN3 | 518 | 612 | 9.31475E-13 |
| 36 | g6698.t1 | CDD | cd00063 | FN3 | 637 | 725 | 6.33175E-10 |
| 21 | g6698.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 31 | 133 | 4.6E-5 |
| 20 | g6698.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 134 | 218 | 1.0E-14 |
| 17 | g6698.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 219 | 315 | 1.2E-18 |
| 18 | g6698.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 316 | 414 | 2.0E-13 |
| 23 | g6698.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 415 | 513 | 5.1E-12 |
| 22 | g6698.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 514 | 627 | 1.8E-15 |
| 19 | g6698.t1 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 629 | 732 | 1.1E-10 |
| 6 | g6698.t1 | PANTHER | PTHR12231 | CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN | 26 | 778 | 3.6E-216 |
| 7 | g6698.t1 | PANTHER | PTHR12231:SF245 | AGAP002802-PA | 26 | 778 | 3.6E-216 |
| 10 | g6698.t1 | PRINTS | PR01838 | Neural cell adhesion molecule signature | 128 | 155 | 2.0E-8 |
| 9 | g6698.t1 | PRINTS | PR01838 | Neural cell adhesion molecule signature | 203 | 231 | 2.0E-8 |
| 8 | g6698.t1 | PRINTS | PR01838 | Neural cell adhesion molecule signature | 293 | 322 | 2.0E-8 |
| 4 | g6698.t1 | Pfam | PF07679 | Immunoglobulin I-set domain | 147 | 210 | 6.8E-12 |
| 3 | g6698.t1 | Pfam | PF07679 | Immunoglobulin I-set domain | 225 | 312 | 1.3E-12 |
| 1 | g6698.t1 | Pfam | PF13927 | Immunoglobulin domain | 315 | 404 | 6.6E-8 |
| 2 | g6698.t1 | Pfam | PF07679 | Immunoglobulin I-set domain | 436 | 512 | 5.5E-7 |
| 5 | g6698.t1 | Pfam | PF00041 | Fibronectin type III domain | 523 | 605 | 3.2E-10 |
| 26 | g6698.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 21 | - |
| 27 | g6698.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 3 | - |
| 28 | g6698.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 4 | 16 | - |
| 30 | g6698.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 17 | 21 | - |
| 25 | g6698.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 22 | 748 | - |
| 29 | g6698.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 749 | 771 | - |
| 24 | g6698.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 772 | 831 | - |
| 54 | g6698.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 27 | 122 | 7.74 |
| 53 | g6698.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 128 | 217 | 10.843 |
| 52 | g6698.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 224 | 311 | 12.731 |
| 56 | g6698.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 316 | 416 | 9.01 |
| 55 | g6698.t1 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 421 | 513 | 7.522 |
| 50 | g6698.t1 | ProSiteProfiles | PS50853 | Fibronectin type-III domain profile. | 517 | 615 | 15.44 |
| 51 | g6698.t1 | ProSiteProfiles | PS50853 | Fibronectin type-III domain profile. | 633 | 735 | 11.306 |
| 41 | g6698.t1 | SMART | SM00409 | IG_3c | 35 | 132 | 0.002 |
| 48 | g6698.t1 | SMART | SM00408 | igc2_5 | 41 | 118 | 2.7 |
| 42 | g6698.t1 | SMART | SM00409 | IG_3c | 139 | 221 | 5.7E-6 |
| 46 | g6698.t1 | SMART | SM00408 | igc2_5 | 145 | 208 | 1.6E-8 |
| 39 | g6698.t1 | SMART | SM00409 | IG_3c | 230 | 313 | 5.7E-7 |
| 45 | g6698.t1 | SMART | SM00408 | igc2_5 | 236 | 302 | 1.0E-13 |
| 38 | g6698.t1 | SMART | SM00409 | IG_3c | 321 | 418 | 4.0E-4 |
| 49 | g6698.t1 | SMART | SM00408 | igc2_5 | 327 | 407 | 0.016 |
| 40 | g6698.t1 | SMART | SM00409 | IG_3c | 429 | 515 | 51.0 |
| 47 | g6698.t1 | SMART | SM00408 | igc2_5 | 435 | 504 | 0.31 |
| 43 | g6698.t1 | SMART | SM00060 | FN3_2 | 518 | 602 | 1.1E-5 |
| 44 | g6698.t1 | SMART | SM00060 | FN3_2 | 628 | 722 | 0.063 |
| 13 | g6698.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 142 | 226 | 1.22E-15 |
| 15 | g6698.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 217 | 313 | 2.26E-17 |
| 12 | g6698.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 312 | 423 | 2.14E-15 |
| 14 | g6698.t1 | SUPERFAMILY | SSF48726 | Immunoglobulin | 416 | 518 | 1.09E-12 |
| 11 | g6698.t1 | SUPERFAMILY | SSF49265 | Fibronectin type III | 517 | 725 | 1.34E-24 |
| 16 | g6698.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 21 | - |
| 37 | g6698.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 749 | 771 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0007155 | cell adhesion | BP |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K06491 (neural cell adhesion molecule)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
