General information for g673.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Egl nine homolog 1.
Parent gene
- The parent gene g673 is located on chr_3: 5207909..5209193 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g673 | g673.t1 | TTS | g673.t1 | 5204947 | 5204947 |
| chr_3 | g673 | g673.t1 | isoform | g673.t1 | 5205183 | 5208765 |
| chr_3 | g673 | g673.t1 | exon | g673.t1.exon1 | 5205183 | 5205208 |
| chr_3 | g673 | g673.t1 | cds | g673.t1.CDS1 | 5205183 | 5205208 |
| chr_3 | g673 | g673.t1 | exon | g673.t1.exon2 | 5205268 | 5205458 |
| chr_3 | g673 | g673.t1 | cds | g673.t1.CDS2 | 5205268 | 5205458 |
| chr_3 | g673 | g673.t1 | exon | g673.t1.exon3 | 5205522 | 5205661 |
| chr_3 | g673 | g673.t1 | cds | g673.t1.CDS3 | 5205522 | 5205661 |
| chr_3 | g673 | g673.t1 | exon | g673.t1.exon4 | 5206268 | 5206348 |
| chr_3 | g673 | g673.t1 | cds | g673.t1.CDS4 | 5206268 | 5206348 |
| chr_3 | g673 | g673.t1 | exon | g673.t1.exon5 | 5207468 | 5207590 |
| chr_3 | g673 | g673.t1 | cds | g673.t1.CDS5 | 5207468 | 5207590 |
| chr_3 | g673 | g673.t1 | exon | g673.t1.exon6 | 5207673 | 5207832 |
| chr_3 | g673 | g673.t1 | cds | g673.t1.CDS6 | 5207673 | 5207832 |
| chr_3 | g673 | g673.t1 | exon | g673.t1.exon7 | 5207900 | 5208765 |
| chr_3 | g673 | g673.t1 | cds | g673.t1.CDS7 | 5207900 | 5208765 |
| chr_3 | g673 | g673.t1 | TSS | g673.t1 | 5209122 | 5209122 |
Sequences
>g673.t1 Gene=g673 Length=1587
ATGTTAGTCAACAGAATTCATAAGCCATATCTTTGTAATATATGTAAAAAAGCGACGGGT
GTGAAGGCATGTAAATGTCAGAAAGCATTCTACTGTTCGCGTAATTGCCAAAAAATTGAT
TGGAATGTACACAAGAGCGATTGTCTTTATAAATTCACAGATCCTCGTGCAATCACAACA
AAGAAAACGAACAACAGTACAGACCCAAATAATACTTCACATGATATATTGCTGCAAGAA
CAACAACAACAACGATTCACAAATTCGGATAACGCAACACTAATGCAACAGACTGAACAA
CAACACGAACGTACGATTACATTAGACAGAGAGAGACGGACATATGATCCAACACCACTA
CAATATCAACAACCGCATGTCACTTATACACCTAACACATTTACGACAACATCAACACAT
ATACAACATAGCACATCGACATCGAATGAGGCAGTAGATGATTTTGAAGAAAATTTGTTC
AATTCATTGATGTATTCAGTCGTGAACGAAAGTACTGAGCAAGAAATACTGAAAAATTTA
AACATACGTGCAGACGATTTACTTACAACATATTCACTGGATAGCGATATTTCTTCATCA
TTAAACGATACTCAATCATTGAAAGAGTACGTGCCAAATTTAAATTCAGTCGATCAAACG
CTAAGCGACAAAATTTTCAATCAAGAAGCCTTCGAAATTAGACCTGAAACGCAAAAATTA
TTAGCTGAAACAAAAGAAACACTAGAAAAAGAATTGTCATTGTTTTGTGAGAATAATCTG
AATGAGAAGGATCAAATGATGCAGTTAGGCACAACAAATCCAAAATATGTTACCCACACG
AAAGTTCAAGATAATAATGTTATGAGAACTCCGGATGAACAGATGGCTTTGGAAGAAATG
AGTTGTACTTTAATTCGAGACTTGAATGAATACGGAGTTTGCGTGCTTGACAGTTTTGTC
GGTGAAGAGCGTGGACTTAAAGTCCTGGAAGAGGTCAAATGCATGTATAAAGCGGGATTA
TTCAGAGATGGACAACTTGTGTCAACAACAAAATCAAAATTAGATCATAAGCATATTAGA
AGTGATAAAATAATGTGGGTCGATGGAAAAGAACAAGGCCTTTATAATATCAAATATCTG
ATGAATCAGGTGGACGCTGTGATAACATTAGCGAATCGTATGAGAAACAACGGAAAATTA
GGACAATATAACATACGTGAGAGAACGAAGGCAATGGTTGCGGTCTATGAAGGAAAAGGA
TCACATTATGTGAAACATGTGGACAATCCAAATAAAGATGGTCGTTGCATTACCTGCATA
TATTATTTAAATGTCAACTGGAATGTGCAAGAGAGTGGCGGTTTGTTGAGAATTTTTCCC
GATGGTTGGGTGGATCGAATTGCTGACATTGAGCCAATTTTCGATCGAATAACCTTTTTC
TGGAGTGACAGACGAAATCCTCATGAAGTACAACCTGCACATAGAACAAGATATGCCATA
ACACTTTGGTATTTTGACGCACATGAACGTGAAGCGGCTGTTAGAAAATACAAAAAAGAC
TGTGAAAACCTGTTGAAAGCAGCTTGA
>g673.t1 Gene=g673 Length=528
MLVNRIHKPYLCNICKKATGVKACKCQKAFYCSRNCQKIDWNVHKSDCLYKFTDPRAITT
KKTNNSTDPNNTSHDILLQEQQQQRFTNSDNATLMQQTEQQHERTITLDRERRTYDPTPL
QYQQPHVTYTPNTFTTTSTHIQHSTSTSNEAVDDFEENLFNSLMYSVVNESTEQEILKNL
NIRADDLLTTYSLDSDISSSLNDTQSLKEYVPNLNSVDQTLSDKIFNQEAFEIRPETQKL
LAETKETLEKELSLFCENNLNEKDQMMQLGTTNPKYVTHTKVQDNNVMRTPDEQMALEEM
SCTLIRDLNEYGVCVLDSFVGEERGLKVLEEVKCMYKAGLFRDGQLVSTTKSKLDHKHIR
SDKIMWVDGKEQGLYNIKYLMNQVDAVITLANRMRNNGKLGQYNIRERTKAMVAVYEGKG
SHYVKHVDNPNKDGRCITCIYYLNVNWNVQESGGLLRIFPDGWVDRIADIEPIFDRITFF
WSDRRNPHEVQPAHRTRYAITLWYFDAHEREAAVRKYKKDCENLLKAA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g673.t1 | Gene3D | G3DSA:3.30.60.180 | - | 3 | 49 | 2.0E-8 |
| 8 | g673.t1 | Gene3D | G3DSA:2.60.120.620 | q2cbj1_9rhob like domain | 284 | 527 | 1.1E-76 |
| 3 | g673.t1 | PANTHER | PTHR12907 | EGL NINE HOMOLOG-RELATED | 9 | 523 | 1.3E-109 |
| 1 | g673.t1 | Pfam | PF01753 | MYND finger | 12 | 48 | 3.7E-8 |
| 2 | g673.t1 | Pfam | PF13640 | 2OG-Fe(II) oxygenase superfamily | 412 | 504 | 1.3E-18 |
| 9 | g673.t1 | ProSiteProfiles | PS50865 | Zinc finger MYND-type profile. | 12 | 48 | 11.127 |
| 10 | g673.t1 | ProSiteProfiles | PS51471 | Fe(2+) 2-oxoglutarate dioxygenase domain profile. | 407 | 506 | 10.257 |
| 5 | g673.t1 | SMART | SM00702 | p4hc | 311 | 505 | 1.7E-31 |
| 4 | g673.t1 | SUPERFAMILY | SSF144232 | HIT/MYND zinc finger-like | 6 | 50 | 3.84E-8 |
| 6 | g673.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 23 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | MF |
| GO:0005506 | iron ion binding | MF |
| GO:0055114 | NA | NA |
| GO:0031418 | L-ascorbic acid binding | MF |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K09592 (hypoxia-inducible factor prolyl hydroxylase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
