General information for g6767.t12
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative THO complex subunit 4.
Parent gene
- The parent gene g6767 is located on chr_2: 18541523..18543877 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6767 | g6767.t12 | TSS | g6767.t12 | 18539688 | 18539688 |
| chr_2 | g6767 | g6767.t12 | isoform | g6767.t12 | 18539830 | 18541940 |
| chr_2 | g6767 | g6767.t12 | exon | g6767.t12.exon1 | 18539830 | 18541114 |
| chr_2 | g6767 | g6767.t12 | cds | g6767.t12.CDS1 | 18540916 | 18541114 |
| chr_2 | g6767 | g6767.t12 | exon | g6767.t12.exon2 | 18541186 | 18541377 |
| chr_2 | g6767 | g6767.t12 | cds | g6767.t12.CDS2 | 18541186 | 18541377 |
| chr_2 | g6767 | g6767.t12 | exon | g6767.t12.exon3 | 18541444 | 18541940 |
| chr_2 | g6767 | g6767.t12 | cds | g6767.t12.CDS3 | 18541444 | 18541571 |
| chr_2 | g6767 | g6767.t12 | TTS | g6767.t12 | 18541941 | 18541941 |
Sequences
>g6767.t12 Gene=g6767 Length=1974
ATGGATAAGATTGAGATGAGTTTAGATGACATCATAAAACAAAACAAAAAGACATCGGGA
AAAAATCGTCGACCAGGCCTTAGTAATAAGAAAACTACTTCTCCGAATAAGACAAAGAAA
TTTGGAAATGGCGGAATTTTGAAAGGCCGTGGTCGTGGTGGAATCGCACGCTCAAAGTAT
ACTCGGGTAAGCTGAAAACATCAATTTCTGATGAGAAAATTATGAAATTAAAAAATCCTG
AGAAAAAATATTCCAATATGGAGGATTTCATGAGTAAAAGAGAAAAGTTCAAAGAGAGGG
AGAAAGAGAGATTATGATTATGAAGAAGAAGGAAAAGTTCTGAATGAAATTCATAACATG
GTGAAATTATAGGCAGAAGAAGAATATAAAGTACATATATTATATTTTTGAAAAGTTCTT
GATATAGAAATTTGGCGAATGATTAATCAACACATCATTAAAGCAATTGAAACAAACGTT
TTAAAAGTTAAATGATTAAGAAAAGAAGACTCAAGAAAATAATTAAATAATGGTTTTGTG
TGTATTTTGTGGTGGTGAAGAAGATTGTAATTTGTGTGGATTCGCGATTTAGAAATGCAT
TGAAAAAGTACTTGTGGGACAATAATATTATAATTTCTAGTGCAATTTGAATGCTCATCA
AAACAACGAGCGTTCAATAGCACTATATTTACTGGTATTTATCAGTAAAATAGAAAAAAG
AACATTATTTTTGAGTTATATACATATATGTGGTGTTGATTCATTAATTTCGTTAGTTAT
TCGCGTTATGCATATTATATTTTGTCTATCCCAAACACACTCTAATAGTCTATTAGCAGC
CATGATGAAATTTCTAGAAAATATCTACCTACAAATCTACGCAATGATTTGGAAAGATTG
ATTTTCAGTCCAGTTTTGAGATCAGAACGTATATACATTTTATCAAGCTCTCGGCAACTA
TCTCGTAGATGAACATTCTTCTTGAAAATACCCTACCTATTAAAATCTGGCTTCAATTCA
CGGCAAAATCCAACAAAAACCAAAATCCATTTCTAGGGTGATGTTAACAGCGCATGGAAA
CACGATATGTATGAAGGTGGACGAAAATTGGGAGGAGCATTGGCATTATCAACAGGCGGT
AATCGTGGAGTAGGAGGAACCACAAAACTCGTAGTGTCAAATCTGGATTTCAGCGTTTCT
GACTCGGATATTAATGAATTGTTCCAAGAATTTGGACCTTTAAAAGCTGCATCCGTTCAC
TATGACCGTTCCGGCAGATCTCTTGGAACAGCAGATGTTATTTTTGAACGCCGTAACGAC
GCTTTAAAGGCTATGAAAACATACAATGGCGTGCCTCTTGATGGACGGCCTATGAACATA
TTGATGGCTACTTCAGAAATTGCATCAGCAAGAGTGCAAAGAGTACCAAGTTTTTCAACT
AATAAAGGAGGAGCTCGTTCACCACGCAAACCAATAGGAGCTGGAAGAAAACCATTCAAA
CGAAATTTTGCGGGAGGAGCACAAAAGCGTGGTGGTGGAAAAAAACCAGAAGTCACCATT
GATCAATTAAATGCTGAACTTGATGCGTATACAATGCAATCATAAATAGTATCAGTTTTT
GACCCTACACTGTGAATTAGAATTATATATATATCAACAGTGTATGAAATGGATAATATT
ATAAATAATAAGAATTATAAAAAAAAATTGTGACATTTAATTTTGAAAACAATTCTCTTT
ATGAGTTAAGAAGTAAGCTGCAACAATAACAGCTTTCATTGATTTTAATTTGTAAGCTTT
TTCTCATCTTCTCTCAAATTTTTTAAGTTGAAAAAATAAACCAAAATTCAGAAATACATA
TGACGATATTAAAAAATTTTCTTTAACATCATAACTATAAAACAATACTGATAAATTGTT
AAAGAAAGAAGAATTGTGGAATAAAAATTATAAAAAATATTTTTTTCTGAAAAT
>g6767.t12 Gene=g6767 Length=172
MYEGGRKLGGALALSTGGNRGVGGTTKLVVSNLDFSVSDSDINELFQEFGPLKAASVHYD
RSGRSLGTADVIFERRNDALKAMKTYNGVPLDGRPMNILMATSEIASARVQRVPSFSTNK
GGARSPRKPIGAGRKPFKRNFAGGAQKRGGGKKPEVTIDQLNAELDAYTMQS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g6767.t12 | CDD | cd12680 | RRM_THOC4 | 26 | 100 | 4.3212E-49 |
| 6 | g6767.t12 | Gene3D | G3DSA:3.30.70.330 | - | 14 | 110 | 1.4E-22 |
| 9 | g6767.t12 | MobiDBLite | mobidb-lite | consensus disorder prediction | 115 | 158 | - |
| 3 | g6767.t12 | PANTHER | PTHR19965:SF35 | THO COMPLEX SUBUNIT 4 | 26 | 168 | 6.3E-41 |
| 4 | g6767.t12 | PANTHER | PTHR19965 | RNA AND EXPORT FACTOR BINDING PROTEIN | 26 | 168 | 6.3E-41 |
| 2 | g6767.t12 | Pfam | PF00076 | RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 28 | 96 | 1.8E-14 |
| 1 | g6767.t12 | Pfam | PF13865 | C-terminal duplication domain of Friend of PRMT1 | 118 | 170 | 1.7E-5 |
| 10 | g6767.t12 | ProSiteProfiles | PS50102 | Eukaryotic RNA Recognition Motif (RRM) profile. | 26 | 103 | 15.937 |
| 8 | g6767.t12 | SMART | SM00360 | rrm1_1 | 27 | 99 | 2.9E-17 |
| 5 | g6767.t12 | SUPERFAMILY | SSF54928 | RNA-binding domain, RBD | 24 | 129 | 1.48E-23 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003676 | nucleic acid binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
