General information for g6783.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Xanthine dehydrogenase.
Parent gene
- The parent gene g6783 is located on chr_2: 18590081..18593606 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6783 | g6783.t1 | TTS | g6783.t1 | 18589994 | 18589994 |
| chr_2 | g6783 | g6783.t1 | isoform | g6783.t1 | 18590081 | 18593606 |
| chr_2 | g6783 | g6783.t1 | exon | g6783.t1.exon1 | 18590081 | 18590265 |
| chr_2 | g6783 | g6783.t1 | cds | g6783.t1.CDS1 | 18590081 | 18590265 |
| chr_2 | g6783 | g6783.t1 | exon | g6783.t1.exon2 | 18590338 | 18592171 |
| chr_2 | g6783 | g6783.t1 | cds | g6783.t1.CDS2 | 18590338 | 18592171 |
| chr_2 | g6783 | g6783.t1 | exon | g6783.t1.exon3 | 18592233 | 18593346 |
| chr_2 | g6783 | g6783.t1 | cds | g6783.t1.CDS3 | 18592233 | 18593346 |
| chr_2 | g6783 | g6783.t1 | exon | g6783.t1.exon4 | 18593416 | 18593606 |
| chr_2 | g6783 | g6783.t1 | cds | g6783.t1.CDS4 | 18593416 | 18593606 |
| chr_2 | g6783 | g6783.t1 | TSS | g6783.t1 | NA | NA |
Sequences
>g6783.t1 Gene=g6783 Length=3324
ATGGAAGAAGTTGAGAATTCGTTTGGTGGAAATATATGCAGATGTACTGGTTATCGACCA
ATTTTAGATGCATTCAAATCACTTGCAATTGATGCTGATAAGAATCTTTTGGATGCATGC
AAGGACATTGAAGATTTAAGTGATATTAAAATGTGTCCAAAATCAGGAAATCCTTGTTCT
GGCCAAATGCATTTACACTATCATAATGAAATTTTCAAAATTTTTGAAACTATTGGAGAG
AAACCATATATTTTGATTGGAGGCAACACAGCTCATGGTGTATATCGTCGATCAACAGAT
TTGAAAGTTTTCGTTGATATTTCAAGTGTTGAAGAGTTGAAAGCTTACCAAGTTACTGAG
AATTCATTAGAAATTGGTGGGGCAGTAACTTTAACTGAAGCAATGGAGATTTTTACAAAA
GTTGCAAATGAAAATAAAAATTTTCAATATTTGCATGAAATCGTCAAACATTTTGATTTG
ATAGCTAATGTACCAGTGCGAAATAATGGAACGCTTGCTGGAAATTTAATGATAAAAAAT
GCACACAACGAATTTCCTTCTGATATTTTCATTTGTTTTGAAGCTATTGGTACAATGATC
AATATTTGGGATGGTTCAAAAAATGAGATTCAAATAAGTTTGAATCATTTTATTTCTACA
GATATGAATAAGAAAGTTTTGACTAAAATTACATTGCCAGCAATTGATCCAGTTAAATTC
TTTTATCGCTCTTATAAAATAATGCCTCGAGCTCAAAACGCACATGCATATGTCAATGCA
ATTTTTGTGCAATTGAATGACTCGAAAGTTATTTCAGCTAAAATTTGCTTTGGTGGTATT
GATCCTAAATTTGTACATGCTACAAACACTGAAACATTCTTGATTGGTGAAAATCTTTTT
GAGAACAGCACTTTACAGCGTGCTTTAGCAATATTAAATGATGAACTTAAACCAGACTGG
GTTCTACCTGATGCTTCACCAGAATATCGTAAAAATCTTGCTCTTGCACTTTTCTATAAA
TTTATTCTTAATATTGCACCAAATGAAAAAGTGGTTGCAAAATTCAAAAGTGGTGGAGAA
ATTCTTAAACGTGATTTATCATCAGGCACTCAAACTTTTGACACATATAAACAAAACTGG
CCTCTTACCAAAAATATTCCTAAAATTGAAGCAGATATTCAATGTACTGGTGAAGCTAAA
TATATAAATGACCATCCACCACTTCCAAATGAACTTCATGCTGCTTTCGTGACCGCAAAG
AATGTTCATGGAGAGATTTTAAATATTGATGCTAGCAAAGCTTTGAAAATGCCAGGTGTA
GTTGCATTCTTTTCAGCAAAAGACATTCCAGGTACAAATACATTCATGCCACCAAACTAT
TTATTTGTTTCGGAACCAGAAGAGATTTTTTGCAGTTCAAAAGTACTTTTTTATAATCAA
CCTGTTGGTGTCATTGTAGCAAAGACCTTCGAATTAGCAAATAAAGCTGCAGACATGATT
ACTATTACATATGTTGAAGATAACAATAAATCAAAAGTAATGACCTCTATTATGGAAGTT
AAAGATGATAAACTACGTACTTTAATATGTCCTGAGTACAGTGTAGAAGGACAACAAGGT
GACAATATTCAACACTCAGAAAGCATTACCGGTAATTTCCATTTCGATTCGCAATACCAT
TACACTATGGAAACGCAATCATGCTTATGCATTCCTATTGAAGACGGAATTGATGTTTAT
TCTTCAACACAATGGATGGATGCAACACAAATTGCTGTTGCGGAAACTCTCTTGTTGCCA
AATAATGCAGTAAACATGAAAGTTCGCCGACTAGGTGGTGGCTTTGGCTCAAAAATTTCA
CGACCAGCACAAATTGCTTGTGCTTCAGCTCTTGCTGCTTATTTATTGAATCGACCTGTA
AGATTTGTAATGACTATGGAGGCAAATATGAATGTCTTTGGCAAAAGACTTCCATGCTAT
AGTGAATATAAAGTTGAAGTTGATAAAAACGGAAGAATTTTGAAATTAAGAAACGAATAT
ATTGAAGATTATGGATGTTCTTTCAATGAGCCAGCTTATTTAACTACTGGTTTCTTCAAT
AACTGTTATGACAATAAATATTTTAATGTTATAGCAAAAAAAGCAAAAACTGATAAAGCA
AGTAATACATGGTGCCGTGGACCAGGTACACTTGAAGGAATTGCAATGATTGAAAATATT
ATGGAGCACATTTCAAGAAAAGTTAATCGAGATCCAATTGATGTTCGGCTTGAAAACATT
CCTAAAGAAAGTGTCATCAAGAAACTTTTAAAAGAGTTCATTCAAAAAACAAATTATCAC
GACCGCAAAAAAGAAATCACAAACTATAATTTAAATAACCGCTGGATTAAACGAGGTATT
GCAATAGTCCCAATTAAATTCCACATAGAATATTTTGGTAGTTTACATGCTTTGGTCTCA
ATATATCATCGAGATGGGTCAGTATCTGTGACAGTTGGGGGTATCGAAATGGGTCAAGGT
CTTAATACAAAAGTAGCACAAACTGCTGCTTATGCACTTGGCATTCCACTTGAAAAAGTT
AGTGTGAAACCATCAAATACACTCACAGCACCAAATGCAATAGTGACAGGTGGAAGCATT
GGTAGTGAAATTTCATGCCATGCTATTAAAAAAGCTTGCGATATTTTAAATGAACGCCTC
AAACCAATAAAAGAGCAGAATACAGACTCTAATTGGAACGAATTAATTGAAAAAGCTTAT
GTAGCGGACGTTGATTTGTCTGCAAATTACATGTATAAGTCTGCAGATGTTGAAGAATAT
CAAGTATGGGGAGCATCATGTTGTGAACTTGAAGTTGATATTCTTACTGGAAATATTTTA
ATTAAACGAGTTGACATCATGGAAGATGTCGGTGAATCATTGAGCCCTGGAATCGATATT
GGACAAATTGAAGGTGGATTTGTTATGGGACTTGGTTATTGGTTAACTGAAAATTTAATT
TATGATCGTATAACTGGAGAATTATTGACTAATCGTTCATGGAATTATAAACCACCAGGT
GCAAAGGATATTCCAATTGATTTTCGAATAAGTTTTCTAAGCAAAAGCTCTAATCCATTT
GGTGTATTAAGATCAAAAGCTGTTGGAGAGCCTCCACTTGTTGCTTCTGTTGTGGTATTA
TTTGCACTGCGACATGCGCTTGATTCTGCTCGCAATGACTCTGGTCGAAAAAATGATGAA
TACTATCAACTAGATGCACCGGCTACGAGTGAGAAAATATTTTTGACAGCAAATAACAAA
CCTGAAATGTTTCTACTCTCTTAA
>g6783.t1 Gene=g6783 Length=1107
MEEVENSFGGNICRCTGYRPILDAFKSLAIDADKNLLDACKDIEDLSDIKMCPKSGNPCS
GQMHLHYHNEIFKIFETIGEKPYILIGGNTAHGVYRRSTDLKVFVDISSVEELKAYQVTE
NSLEIGGAVTLTEAMEIFTKVANENKNFQYLHEIVKHFDLIANVPVRNNGTLAGNLMIKN
AHNEFPSDIFICFEAIGTMINIWDGSKNEIQISLNHFISTDMNKKVLTKITLPAIDPVKF
FYRSYKIMPRAQNAHAYVNAIFVQLNDSKVISAKICFGGIDPKFVHATNTETFLIGENLF
ENSTLQRALAILNDELKPDWVLPDASPEYRKNLALALFYKFILNIAPNEKVVAKFKSGGE
ILKRDLSSGTQTFDTYKQNWPLTKNIPKIEADIQCTGEAKYINDHPPLPNELHAAFVTAK
NVHGEILNIDASKALKMPGVVAFFSAKDIPGTNTFMPPNYLFVSEPEEIFCSSKVLFYNQ
PVGVIVAKTFELANKAADMITITYVEDNNKSKVMTSIMEVKDDKLRTLICPEYSVEGQQG
DNIQHSESITGNFHFDSQYHYTMETQSCLCIPIEDGIDVYSSTQWMDATQIAVAETLLLP
NNAVNMKVRRLGGGFGSKISRPAQIACASALAAYLLNRPVRFVMTMEANMNVFGKRLPCY
SEYKVEVDKNGRILKLRNEYIEDYGCSFNEPAYLTTGFFNNCYDNKYFNVIAKKAKTDKA
SNTWCRGPGTLEGIAMIENIMEHISRKVNRDPIDVRLENIPKESVIKKLLKEFIQKTNYH
DRKKEITNYNLNNRWIKRGIAIVPIKFHIEYFGSLHALVSIYHRDGSVSVTVGGIEMGQG
LNTKVAQTAAYALGIPLEKVSVKPSNTLTAPNAIVTGGSIGSEISCHAIKKACDILNERL
KPIKEQNTDSNWNELIEKAYVADVDLSANYMYKSADVEEYQVWGASCCELEVDILTGNIL
IKRVDIMEDVGESLSPGIDIGQIEGGFVMGLGYWLTENLIYDRITGELLTNRSWNYKPPG
AKDIPIDFRISFLSKSSNPFGVLRSKAVGEPPLVASVVVLFALRHALDSARNDSGRKNDE
YYQLDAPATSEKIFLTANNKPEMFLLS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 21 | g6783.t1 | Gene3D | G3DSA:1.10.150.120 | - | 1 | 75 | 0.000 |
| 14 | g6783.t1 | Gene3D | G3DSA:3.30.465.10 | - | 109 | 234 | 0.000 |
| 15 | g6783.t1 | Gene3D | G3DSA:3.30.390.50 | - | 239 | 349 | 0.000 |
| 20 | g6783.t1 | Gene3D | G3DSA:3.90.1170.50 | - | 415 | 512 | 0.000 |
| 19 | g6783.t1 | Gene3D | G3DSA:3.30.365.10 | Aldehyde Oxidoreductase; domain 4 | 513 | 764 | 0.000 |
| 18 | g6783.t1 | Gene3D | G3DSA:3.30.365.10 | Aldehyde Oxidoreductase; domain 4 | 560 | 653 | 0.000 |
| 17 | g6783.t1 | Gene3D | G3DSA:3.30.365.10 | Aldehyde Oxidoreductase; domain 4 | 765 | 1093 | 0.000 |
| 16 | g6783.t1 | Gene3D | G3DSA:3.30.365.10 | Aldehyde Oxidoreductase; domain 4 | 812 | 937 | 0.000 |
| 5 | g6783.t1 | PANTHER | PTHR11908:SF132 | ALDEHYDE OXIDASE 1-RELATED | 1 | 1104 | 0.000 |
| 6 | g6783.t1 | PANTHER | PTHR11908 | XANTHINE DEHYDROGENASE | 1 | 1104 | 0.000 |
| 23 | g6783.t1 | PIRSF | PIRSF000127 | Xanthine_dh | 1 | 1107 | 0.000 |
| 1 | g6783.t1 | Pfam | PF00941 | FAD binding domain in molybdopterin dehydrogenase | 71 | 234 | 0.000 |
| 3 | g6783.t1 | Pfam | PF03450 | CO dehydrogenase flavoprotein C-terminal domain | 243 | 344 | 0.000 |
| 4 | g6783.t1 | Pfam | PF01315 | Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain | 396 | 506 | 0.000 |
| 2 | g6783.t1 | Pfam | PF02738 | Molybdopterin-binding domain of aldehyde dehydrogenase | 543 | 1025 | 0.000 |
| 22 | g6783.t1 | ProSiteProfiles | PS51387 | PCMH-type FAD-binding domain profile. | 54 | 237 | 18.113 |
| 12 | g6783.t1 | SMART | SM01092 | CO_deh_flav_C_2 | 243 | 345 | 0.000 |
| 13 | g6783.t1 | SMART | SM01008 | Ald_Xan_dh_C_2 | 396 | 508 | 0.000 |
| 8 | g6783.t1 | SUPERFAMILY | SSF47741 | CO dehydrogenase ISP C-domain like | 1 | 50 | 0.000 |
| 11 | g6783.t1 | SUPERFAMILY | SSF56176 | FAD-binding/transporter-associated domain-like | 74 | 234 | 0.000 |
| 7 | g6783.t1 | SUPERFAMILY | SSF55447 | CO dehydrogenase flavoprotein C-terminal domain-like | 240 | 348 | 0.000 |
| 10 | g6783.t1 | SUPERFAMILY | SSF54665 | CO dehydrogenase molybdoprotein N-domain-like | 370 | 507 | 0.000 |
| 9 | g6783.t1 | SUPERFAMILY | SSF56003 | Molybdenum cofactor-binding domain | 548 | 1098 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005506 | iron ion binding | MF |
| GO:0050660 | flavin adenine dinucleotide binding | MF |
| GO:0055114 | NA | NA |
| GO:0071949 | FAD binding | MF |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K03520 (aerobic carbon-monoxide dehydrogenase large subunit)
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
