General information for g6793.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Tryptophan 5-hydroxylase.
Parent gene
- The parent gene g6793 is located on chr_2: 18722558..18724746 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6793 | g6793.t3 | isoform | g6793.t3 | 18722558 | 18724746 |
| chr_2 | g6793 | g6793.t3 | exon | g6793.t3.exon1 | 18722558 | 18722761 |
| chr_2 | g6793 | g6793.t3 | exon | g6793.t3.exon2 | 18723704 | 18724124 |
| chr_2 | g6793 | g6793.t3 | cds | g6793.t3.CDS1 | 18724011 | 18724124 |
| chr_2 | g6793 | g6793.t3 | exon | g6793.t3.exon3 | 18724348 | 18724596 |
| chr_2 | g6793 | g6793.t3 | cds | g6793.t3.CDS2 | 18724348 | 18724596 |
| chr_2 | g6793 | g6793.t3 | exon | g6793.t3.exon4 | 18724674 | 18724746 |
| chr_2 | g6793 | g6793.t3 | cds | g6793.t3.CDS3 | 18724674 | 18724700 |
| chr_2 | g6793 | g6793.t3 | TTS | g6793.t3 | 18724903 | 18724903 |
| chr_2 | g6793 | g6793.t3 | TSS | g6793.t3 | NA | NA |
Sequences
>g6793.t3 Gene=g6793 Length=947
GGTAAATAATTAGATTTTATGCCAATTTATGCTTGCATTCAACTTTATTTAAATTAAATT
ATGTCATATGTCTCGCTTTTTCTTTATTTTTTCTCACACTTTAAAAGGGGCGTCGTTTTT
CGCGAACTGCATAAACTTTATGTTAAGCATGCTGTTCCTGAATATATGGAGAATTGGCCT
CAACTTGTGAAATATTGCGGATATAGAAGACAATTTGCCACAACTTCAAGACATTAACGT
TTTCTTGAAACGAAAGACAGGATTTCAAGTGAGACCTGTTGCTGGATATCTTTCTCCTCG
TGACTTTTTGTCTGGCTTAGCATTTCGCGTATTCCATTGCACTCAATATATTCGACACTC
TTCAGATCCATTTTATACACCGGGTAAGTATTTCTAGTTAATTGTTTTATTATGCATTTA
AATCTGCTCTCATTAATTACTGACTTAAAATTTTCTTGAAAAATAATTATACTTTACAGA
GCCCGATTGCTGTCATGAATTACTCGGTCATATGCCTCTACTCGCAAATCCATCTTTTGC
ACAATTCTCGCAAGAAATCGGACTAGCTTCATTAGGAGCAAGTGATGAAGATGTCTCAAA
ATTAGCCACAGTATATCATAAAACAAATGCTTACTATTATACTGATAGTTTTGAGGAAGC
AAAGGAGAAGCTGAGAGATTTTGCTTGTAGCATTCAACGGCCATTCATGGTAAGATATAA
TCCATACACCCAATCAGTTGAAGTACTTAGCAATGCAAAGAAGATTACTGCGGTTGTGAG
TGAATTGAGAGGAGACTTATCAATTGTTTCGACAGCTTTGAAAAAAATATCTGCTTTGGA
CGAGACTTTAGATGTCGATTCGCTATCAAACATGTTAATAATTTTAGATCAATCCAGATA
AATCACCGGTGTCAGAAGGATCTGACAATTCTCAAAAAATTCATTAA
>g6793.t3 Gene=g6793 Length=129
MPLLANPSFAQFSQEIGLASLGASDEDVSKLATVYHKTNAYYYTDSFEEAKEKLRDFACS
IQRPFMVRYNPYTQSVEVLSNAKKITAVVSELRGDLSIVSTALKKISALDETLDVDSLSN
MLIILDQSR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g6793.t3 | Gene3D | G3DSA:1.10.800.10 | Phenylalanine Hydroxylase | 1 | 37 | 0.000 |
| 8 | g6793.t3 | Gene3D | G3DSA:1.10.800.10 | Phenylalanine Hydroxylase | 38 | 111 | 0.000 |
| 4 | g6793.t3 | PANTHER | PTHR11473:SF37 | GH12537P | 1 | 36 | 0.000 |
| 6 | g6793.t3 | PANTHER | PTHR11473 | AROMATIC AMINO ACID HYDROXYLASE | 1 | 36 | 0.000 |
| 3 | g6793.t3 | PANTHER | PTHR11473:SF37 | GH12537P | 39 | 108 | 0.000 |
| 5 | g6793.t3 | PANTHER | PTHR11473 | AROMATIC AMINO ACID HYDROXYLASE | 39 | 108 | 0.000 |
| 2 | g6793.t3 | Pfam | PF00351 | Biopterin-dependent aromatic amino acid hydroxylase | 1 | 36 | 0.000 |
| 1 | g6793.t3 | Pfam | PF00351 | Biopterin-dependent aromatic amino acid hydroxylase | 39 | 104 | 0.000 |
| 10 | g6793.t3 | ProSiteProfiles | PS51410 | Biopterin-dependent aromatic amino acid hydroxylase family profile. | 1 | 129 | 13.331 |
| 7 | g6793.t3 | SUPERFAMILY | SSF56534 | Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 1 | 106 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0009072 | aromatic amino acid family metabolic process | BP |
| GO:0005506 | iron ion binding | MF |
| GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen | MF |
| GO:0004497 | monooxygenase activity | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
