General information for g689.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Filamin-C.
Parent gene
- The parent gene g689 is located on chr_3: 5269092..5271163 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g689 | g689.t2 | isoform | g689.t2 | 5269092 | 5270202 |
| chr_3 | g689 | g689.t2 | exon | g689.t2.exon1 | 5269092 | 5269434 |
| chr_3 | g689 | g689.t2 | cds | g689.t2.CDS1 | 5269093 | 5269434 |
| chr_3 | g689 | g689.t2 | exon | g689.t2.exon2 | 5269494 | 5269744 |
| chr_3 | g689 | g689.t2 | cds | g689.t2.CDS2 | 5269494 | 5269744 |
| chr_3 | g689 | g689.t2 | exon | g689.t2.exon3 | 5269808 | 5270202 |
| chr_3 | g689 | g689.t2 | cds | g689.t2.CDS3 | 5269808 | 5269916 |
| chr_3 | g689 | g689.t2 | TSS | g689.t2 | NA | NA |
| chr_3 | g689 | g689.t2 | TTS | g689.t2 | NA | NA |
Sequences
>g689.t2 Gene=g689 Length=989
CGATTTGTCAGTTGACTTTTGTGATGGCACACACCTTTGTGCATTGGTTGAATCATTGCA
GAAACGAAAATTAAAGCCATCATGGAATAAAAGACCACAGAATCAACATCACTATTTAGA
AAATGCCACAACCGCACTTAATGCCATCGAAGCTGATCACATTAAACTTGTAAACATTGG
CAATGTCGACATCGTCAATGGCAATTTGAAACTTATCCTCGGGCTCATATGGTCACTAAT
TGTACGCTATCAAATTGGCAGAAGTAAATTCCCGCCGAGAAAATTGATGTTAGCATGGCT
TCAGGCTGCTCTACCTGAATGTCGAGTAACAAATCTCACAACTGACTGGAACAGTGGTGT
TTTACTTTCAGCATTGCTAGATTATTGCGAACCAGGTCTATTCCCACACTGGCGTTCGCT
CGATCCAAATCAATCTGTACGTAATTGTGAGAATGCAATGAATATTGCTCATAGAACATT
CGGTGTGCCAAAGGTCCTCGAACCTGAATACCTTGCATCTCCATGGCTCGATGAGTTATC
TGGAATGACTTATTTATCATATTTCATGAAACCTGATGGTCCAGGGTACAATGCATCAAT
GCGATGGGTAAACAGTCAAATTAAAGTGCCAGTTCATAATTTTACGTCTGATTGGAATGA
TGGTCGTGTATTTTGTGAAATAATAAAAGGTTTAGGAGGAAATGCACCAGCACCTGAAAA
AGTAAGTCGAGATCCAGCAATGTGGGAAAGCAATATGAAAAAGGCAATGGATGCTGGAAA
TCGTTTTGGAATTAAACCTGTGCTTTCACCTAAAGATATGACAAGTCCTGATGTTGAACA
TCTTGCAATTATGGCTTATGCAACACATTTACAATGGGTTCAACCTCGACCTCCACTTGC
TGACATGATTGCTGTTCATTTGCAAAGCACAAGCGGAAGAGTTGCTGAACCAACTTATTT
CCGTATTGATGTGCTATCAAAGGACGTTG
>g689.t2 Gene=g689 Length=234
MLAWLQAALPECRVTNLTTDWNSGVLLSALLDYCEPGLFPHWRSLDPNQSVRNCENAMNI
AHRTFGVPKVLEPEYLASPWLDELSGMTYLSYFMKPDGPGYNASMRWVNSQIKVPVHNFT
SDWNDGRVFCEIIKGLGGNAPAPEKVSRDPAMWESNMKKAMDAGNRFGIKPVLSPKDMTS
PDVEHLAIMAYATHLQWVQPRPPLADMIAVHLQSTSGRVAEPTYFRIDVLSKDV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g689.t2 | CDD | cd00014 | CH | 2 | 95 | 0.000 |
| 12 | g689.t2 | Gene3D | G3DSA:1.10.418.10 | - | 1 | 98 | 0.000 |
| 11 | g689.t2 | Gene3D | G3DSA:1.10.418.10 | - | 99 | 205 | 0.000 |
| 4 | g689.t2 | PANTHER | PTHR19961 | FIMBRIN/PLASTIN | 1 | 103 | 0.000 |
| 6 | g689.t2 | PANTHER | PTHR19961:SF58 | ZGC:100997 | 1 | 103 | 0.000 |
| 3 | g689.t2 | PANTHER | PTHR19961 | FIMBRIN/PLASTIN | 105 | 195 | 0.000 |
| 5 | g689.t2 | PANTHER | PTHR19961:SF58 | ZGC:100997 | 105 | 195 | 0.000 |
| 1 | g689.t2 | Pfam | PF00307 | Calponin homology (CH) domain | 2 | 95 | 0.000 |
| 2 | g689.t2 | Pfam | PF00307 | Calponin homology (CH) domain | 104 | 197 | 0.000 |
| 13 | g689.t2 | ProSiteProfiles | PS50021 | Calponin homology (CH) domain profile. | 1 | 98 | 15.549 |
| 14 | g689.t2 | ProSiteProfiles | PS50021 | Calponin homology (CH) domain profile. | 99 | 200 | 6.739 |
| 10 | g689.t2 | SMART | SM00033 | ch_5 | 2 | 93 | 0.000 |
| 9 | g689.t2 | SMART | SM00033 | ch_5 | 100 | 195 | 0.270 |
| 7 | g689.t2 | SUPERFAMILY | SSF47576 | Calponin-homology domain, CH-domain | 1 | 95 | 0.000 |
| 8 | g689.t2 | SUPERFAMILY | SSF47576 | Calponin-homology domain, CH-domain | 105 | 201 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0051015 | actin filament binding | MF |
| GO:0005515 | protein binding | MF |
| GO:0051017 | actin filament bundle assembly | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed