General information for g6899.t46
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Guanine nucleotide-binding protein subunit beta-like protein.
Parent gene
- The parent gene g6899 is located on chr_2: 19757258..19758555 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6899 | g6899.t46 | TSS | g6899.t46 | 19756988 | 19756988 |
| chr_2 | g6899 | g6899.t46 | isoform | g6899.t46 | 19757065 | 19758555 |
| chr_2 | g6899 | g6899.t46 | exon | g6899.t46.exon1 | 19757065 | 19757115 |
| chr_2 | g6899 | g6899.t46 | cds | g6899.t46.CDS1 | 19757065 | 19757115 |
| chr_2 | g6899 | g6899.t46 | exon | g6899.t46.exon2 | 19757217 | 19757398 |
| chr_2 | g6899 | g6899.t46 | cds | g6899.t46.CDS2 | 19757217 | 19757398 |
| chr_2 | g6899 | g6899.t46 | exon | g6899.t46.exon3 | 19757458 | 19757512 |
| chr_2 | g6899 | g6899.t46 | cds | g6899.t46.CDS3 | 19757458 | 19757512 |
| chr_2 | g6899 | g6899.t46 | exon | g6899.t46.exon4 | 19757837 | 19758171 |
| chr_2 | g6899 | g6899.t46 | cds | g6899.t46.CDS4 | 19757837 | 19758171 |
| chr_2 | g6899 | g6899.t46 | exon | g6899.t46.exon5 | 19758336 | 19758555 |
| chr_2 | g6899 | g6899.t46 | cds | g6899.t46.CDS5 | 19758336 | 19758366 |
| chr_2 | g6899 | g6899.t46 | TTS | g6899.t46 | 19758558 | 19758558 |
Sequences
>g6899.t46 Gene=g6899 Length=843
ATGACCGAAACTTTGCAATTAAAAGGAACTCTTATCGGCCATTCAGGATGGAAATATTTT
TGCAATTTCTTTAAATTAGACAAGACTTTGATTGTATGGCGTTTATTGCGTGAAGCTAAT
AGCTACGGTATTCCTCAAAAGCGTTTGTATGGACACAGCCATTTTATCAGTGACGTTGTT
CTCTCATCTGACGGAAATTATGCTCTTTCTGGATCATGGGACAAGACTTTGAGATTGTGG
GATTTGGCAGCAGGAAAATCAACTCGTCGTTTTGAGGATCACACAAAGGATGTGCTCTCA
GTTGCTTTTAGCGCTGACAATCGTCAAATCGTTTCTGGCTCACGCGATAAGACTATTAAA
TTGTGGAATACATTAGCCGAGTGCAAATACACCATTCAAGAAGATGGCCACTCTGACTGG
GTCTCATGCGTTCGTTTCTCACCAAATCAAGTAAATCCAATCATTGTTTCTGCTGGTTGG
GATAAAACTGTTAAGGTCTGGAACTTGGCAAACTGCAAATTGAAGTTGAACCATTACGGT
CACAATGGATACTTGAATACTGTCACTGTTTCACCTGATGGTTCATTGTGCACATCAGGC
GGTAAGGACTACAAGGCTTTGTTGTGTCTCGACAAACGATTCATCAAAGGCTGATCCACC
ACAGTGCTTGTCACTTGCTTGGTCAACTGATGGACAAACTTTGTTTGCCGGCTACAGCGA
TAACAAGATTCGCGTTTGGCAAGTTTCAGTTACTGCTCGTTAAACTTGCATTCAAAATAC
ATTCTTTATACTGCTATAACATAAAGTATATGAATAAAATATCCATGAAATTCTTATTGG
ATA
>g6899.t46 Gene=g6899 Length=217
MTETLQLKGTLIGHSGWKYFCNFFKLDKTLIVWRLLREANSYGIPQKRLYGHSHFISDVV
LSSDGNYALSGSWDKTLRLWDLAAGKSTRRFEDHTKDVLSVAFSADNRQIVSGSRDKTIK
LWNTLAECKYTIQEDGHSDWVSCVRFSPNQVNPIIVSAGWDKTVKVWNLANCKLKLNHYG
HNGYLNTVTVSPDGSLCTSGGKDYKALLCLDKRFIKG
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g6899.t46 | CDD | cd00200 | WD40 | 7 | 203 | 1.74578E-58 |
| 10 | g6899.t46 | Gene3D | G3DSA:2.130.10.10 | - | 5 | 211 | 1.5E-80 |
| 5 | g6899.t46 | PANTHER | PTHR19868 | RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1 | 1 | 208 | 5.2E-98 |
| 8 | g6899.t46 | PRINTS | PR00320 | G protein beta WD-40 repeat signature | 68 | 82 | 3.5E-9 |
| 7 | g6899.t46 | PRINTS | PR00320 | G protein beta WD-40 repeat signature | 110 | 124 | 3.5E-9 |
| 6 | g6899.t46 | PRINTS | PR00320 | G protein beta WD-40 repeat signature | 155 | 169 | 3.5E-9 |
| 3 | g6899.t46 | Pfam | PF00400 | WD domain, G-beta repeat | 45 | 81 | 8.8E-8 |
| 4 | g6899.t46 | Pfam | PF00400 | WD domain, G-beta repeat | 86 | 123 | 4.6E-8 |
| 1 | g6899.t46 | Pfam | PF00400 | WD domain, G-beta repeat | 130 | 168 | 1.1E-6 |
| 2 | g6899.t46 | Pfam | PF00400 | WD domain, G-beta repeat | 177 | 204 | 0.084 |
| 14 | g6899.t46 | ProSitePatterns | PS00678 | Trp-Asp (WD) repeats signature. | 68 | 82 | - |
| 13 | g6899.t46 | ProSitePatterns | PS00678 | Trp-Asp (WD) repeats signature. | 110 | 124 | - |
| 12 | g6899.t46 | ProSitePatterns | PS00678 | Trp-Asp (WD) repeats signature. | 155 | 169 | - |
| 19 | g6899.t46 | ProSiteProfiles | PS50294 | Trp-Asp (WD) repeats circular profile. | 49 | 203 | 36.253 |
| 21 | g6899.t46 | ProSiteProfiles | PS50082 | Trp-Asp (WD) repeats profile. | 49 | 90 | 15.287 |
| 22 | g6899.t46 | ProSiteProfiles | PS50082 | Trp-Asp (WD) repeats profile. | 91 | 123 | 15.22 |
| 20 | g6899.t46 | ProSiteProfiles | PS50082 | Trp-Asp (WD) repeats profile. | 134 | 169 | 13.316 |
| 17 | g6899.t46 | SMART | SM00320 | WD40_4 | 42 | 81 | 3.7E-7 |
| 18 | g6899.t46 | SMART | SM00320 | WD40_4 | 84 | 123 | 4.9E-10 |
| 16 | g6899.t46 | SMART | SM00320 | WD40_4 | 125 | 168 | 2.3E-9 |
| 15 | g6899.t46 | SMART | SM00320 | WD40_4 | 171 | 210 | 3.2 |
| 9 | g6899.t46 | SUPERFAMILY | SSF50978 | WD40 repeat-like | 4 | 205 | 1.76E-49 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
