General information for g6912.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein 5NUC.
Parent gene
- The parent gene g6912 is located on chr_2: 19897594..19902814 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6912 | g6912.t3 | TSS | g6912.t3 | 19891493 | 19891493 |
| chr_2 | g6912 | g6912.t3 | isoform | g6912.t3 | 19891602 | 19895716 |
| chr_2 | g6912 | g6912.t3 | exon | g6912.t3.exon1 | 19891602 | 19891604 |
| chr_2 | g6912 | g6912.t3 | exon | g6912.t3.exon2 | 19894152 | 19894492 |
| chr_2 | g6912 | g6912.t3 | cds | g6912.t3.CDS1 | 19894197 | 19894492 |
| chr_2 | g6912 | g6912.t3 | exon | g6912.t3.exon3 | 19894554 | 19894635 |
| chr_2 | g6912 | g6912.t3 | cds | g6912.t3.CDS2 | 19894554 | 19894635 |
| chr_2 | g6912 | g6912.t3 | exon | g6912.t3.exon4 | 19894736 | 19894989 |
| chr_2 | g6912 | g6912.t3 | cds | g6912.t3.CDS3 | 19894736 | 19894989 |
| chr_2 | g6912 | g6912.t3 | exon | g6912.t3.exon5 | 19895052 | 19895179 |
| chr_2 | g6912 | g6912.t3 | cds | g6912.t3.CDS4 | 19895052 | 19895179 |
| chr_2 | g6912 | g6912.t3 | exon | g6912.t3.exon6 | 19895238 | 19895716 |
| chr_2 | g6912 | g6912.t3 | cds | g6912.t3.CDS5 | 19895238 | 19895716 |
| chr_2 | g6912 | g6912.t3 | TTS | g6912.t3 | NA | NA |
Sequences
>g6912.t3 Gene=g6912 Length=1287
AAGAACATAAGAAGAAGAAAAATTCGACGCGAACAGTCGATAGAGAAAATGTTTTTTTCA
CATTTGACGACAATTGTTCTGCTACTGCTAGCTGTACACACCTTCTCAGCACCGCAAAAG
AAATCAACAGATGAGAACTTTAAATTAATTATTTTACACAACAATGATATGCATGCACGT
TTTGAGCAGACAAACGCAGCGAGCGCAAGATGTACAGACGAAGATCGAGAGAAAAACAAT
TGCTATGGAGGTTTTGCGAGAGTTGCGCACGTTGTGAGAGACTATCGAAAGAGAGCAAAT
ACTGGCGAGATTCCAAGAGTTCTCTATTTGAATGCTGGTGATACGTATACTGGAACACCT
TGGTTTGCATTATTCAAAGATAATATTACGTCTGCTTTTCTTGAATTACTGAAACCTGAT
GCAATTTCACTCGGCAATCACGAGTTTGATGAAGGGACTGAGAATCTTGCAAAATTTCTT
AAAGAAATTGATTTTCCAGTATTAGCAGCAAACTTAGATTTAGAAAAGGAGCCGTCATTG
AAAGTTGACATTCTGAAACCATCACATATTTTCGAGATCGATGGCATCAAAATTGGTGTA
GTAGGTTACTTGACACCTGAAACTAAAGAAGTTGCAAAGGGCAATCAAGTAGAATTTATT
GACGAAATTGAAGCTATTAATAAGGAGGCCGCACGTCTGAAAGAAGAAGGTATTAAAATT
ATAATTGCACTTGGTCATTCTGGAATTGAGCGTGATAAGCAAATTGCTATGGAATGTCCG
GACATTGATTTGATTATTGGTGGACATTCTCATACATTTTTATACAATGGAACCAAGCCC
GATATTGATGAACCTTATGATACTTATCCAATAATGATAGTTCAACGTAATGGAAAGAAA
GTGCCTGTTGTTCAAAGTTATGCTTATACAAAATATCTTGGTTACATTCATCTTGAATTT
GATGGTGAAGGAAATATGGTTGAGATTGATGGAAATCCAATTCTTCTTAATCATGACATT
CCACGTGAACAAGACGTTTTAGATTTACTTCAAAAGTATCGACCAGCAGTATTAGCATTA
CAAACAGAAGTAGTTGGTCAAACTCGAGTCAATTTAGAAGGTTCATGTCGTCGTGTTGAA
TGCAATTTGGGAAATTTCATTGCTGATTCAATGGTAGATTGGAATGCATTGAGATATGAT
GGTATAGGTTGGACAGATGCAGCAATTGGTATCATACAAGGTGGTGGAGTAAGAGCTTCA
ATCACAAGAACAGTCAGTGGAAATATC
>g6912.t3 Gene=g6912 Length=413
MFFSHLTTIVLLLLAVHTFSAPQKKSTDENFKLIILHNNDMHARFEQTNAASARCTDEDR
EKNNCYGGFARVAHVVRDYRKRANTGEIPRVLYLNAGDTYTGTPWFALFKDNITSAFLEL
LKPDAISLGNHEFDEGTENLAKFLKEIDFPVLAANLDLEKEPSLKVDILKPSHIFEIDGI
KIGVVGYLTPETKEVAKGNQVEFIDEIEAINKEAARLKEEGIKIIIALGHSGIERDKQIA
MECPDIDLIIGGHSHTFLYNGTKPDIDEPYDTYPIMIVQRNGKKVPVVQSYAYTKYLGYI
HLEFDGEGNMVEIDGNPILLNHDIPREQDVLDLLQKYRPAVLALQTEVVGQTRVNLEGSC
RRVECNLGNFIADSMVDWNALRYDGIGWTDAAIGIIQGGGVRASITRTVSGNI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 21 | g6912.t3 | CDD | cd07409 | MPP_CD73_N | 33 | 320 | 2.64938E-149 |
| 15 | g6912.t3 | Coils | Coil | Coil | 200 | 220 | - |
| 13 | g6912.t3 | Gene3D | G3DSA:3.60.21.10 | - | 30 | 345 | 1.9E-99 |
| 14 | g6912.t3 | Gene3D | G3DSA:3.90.780.10 | - | 347 | 413 | 8.1E-15 |
| 3 | g6912.t3 | PANTHER | PTHR11575 | 5’-NUCLEOTIDASE-RELATED | 22 | 413 | 2.2E-140 |
| 4 | g6912.t3 | PANTHER | PTHR11575:SF25 | 5’-NUCLEOTIDASE | 22 | 413 | 2.2E-140 |
| 7 | g6912.t3 | PRINTS | PR01607 | Apyrase family signature | 31 | 49 | 3.5E-25 |
| 8 | g6912.t3 | PRINTS | PR01607 | Apyrase family signature | 220 | 237 | 3.5E-25 |
| 5 | g6912.t3 | PRINTS | PR01607 | Apyrase family signature | 239 | 262 | 3.5E-25 |
| 6 | g6912.t3 | PRINTS | PR01607 | Apyrase family signature | 285 | 305 | 3.5E-25 |
| 2 | g6912.t3 | Pfam | PF00149 | Calcineurin-like phosphoesterase | 35 | 256 | 9.6E-13 |
| 1 | g6912.t3 | Pfam | PF02872 | 5’-nucleotidase, C-terminal domain | 348 | 409 | 2.4E-6 |
| 17 | g6912.t3 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 20 | - |
| 18 | g6912.t3 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 5 | - |
| 19 | g6912.t3 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 6 | 16 | - |
| 20 | g6912.t3 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 17 | 20 | - |
| 16 | g6912.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 21 | 413 | - |
| 23 | g6912.t3 | ProSitePatterns | PS00786 | 5’-nucleotidase signature 2. | 123 | 134 | - |
| 10 | g6912.t3 | SUPERFAMILY | SSF56300 | Metallo-dependent phosphatases | 31 | 341 | 6.08E-88 |
| 9 | g6912.t3 | SUPERFAMILY | SSF55816 | 5’-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 347 | 406 | 4.19E-10 |
| 12 | g6912.t3 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 20 | - |
| 22 | g6912.t3 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM | 1 | 20 | - |
| 11 | g6912.t3 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 20 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0046872 | metal ion binding | MF |
| GO:0016787 | hydrolase activity | MF |
| GO:0000166 | nucleotide binding | MF |
| GO:0016788 | hydrolase activity, acting on ester bonds | MF |
| GO:0009166 | nucleotide catabolic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
