General information for g6927.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Sialin.
Parent gene
- The parent gene g6927 is located on chr_2: 20019163..20021439 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_2 | g6927 | g6927.t1 | TTS | g6927.t1 | 20019090 | 20019090 |
| chr_2 | g6927 | g6927.t1 | isoform | g6927.t1 | 20019163 | 20021439 |
| chr_2 | g6927 | g6927.t1 | exon | g6927.t1.exon1 | 20019163 | 20019320 |
| chr_2 | g6927 | g6927.t1 | cds | g6927.t1.CDS1 | 20019163 | 20019320 |
| chr_2 | g6927 | g6927.t1 | exon | g6927.t1.exon2 | 20019372 | 20019408 |
| chr_2 | g6927 | g6927.t1 | cds | g6927.t1.CDS2 | 20019372 | 20019408 |
| chr_2 | g6927 | g6927.t1 | exon | g6927.t1.exon3 | 20019466 | 20019802 |
| chr_2 | g6927 | g6927.t1 | cds | g6927.t1.CDS3 | 20019466 | 20019802 |
| chr_2 | g6927 | g6927.t1 | exon | g6927.t1.exon4 | 20019862 | 20019988 |
| chr_2 | g6927 | g6927.t1 | cds | g6927.t1.CDS4 | 20019862 | 20019988 |
| chr_2 | g6927 | g6927.t1 | exon | g6927.t1.exon5 | 20020047 | 20020154 |
| chr_2 | g6927 | g6927.t1 | cds | g6927.t1.CDS5 | 20020047 | 20020154 |
| chr_2 | g6927 | g6927.t1 | exon | g6927.t1.exon6 | 20020228 | 20020431 |
| chr_2 | g6927 | g6927.t1 | cds | g6927.t1.CDS6 | 20020228 | 20020431 |
| chr_2 | g6927 | g6927.t1 | exon | g6927.t1.exon7 | 20020488 | 20020653 |
| chr_2 | g6927 | g6927.t1 | cds | g6927.t1.CDS7 | 20020488 | 20020653 |
| chr_2 | g6927 | g6927.t1 | exon | g6927.t1.exon8 | 20020711 | 20020894 |
| chr_2 | g6927 | g6927.t1 | cds | g6927.t1.CDS8 | 20020711 | 20020894 |
| chr_2 | g6927 | g6927.t1 | exon | g6927.t1.exon9 | 20020946 | 20021056 |
| chr_2 | g6927 | g6927.t1 | cds | g6927.t1.CDS9 | 20020946 | 20021056 |
| chr_2 | g6927 | g6927.t1 | exon | g6927.t1.exon10 | 20021414 | 20021439 |
| chr_2 | g6927 | g6927.t1 | cds | g6927.t1.CDS10 | 20021414 | 20021439 |
| chr_2 | g6927 | g6927.t1 | TSS | g6927.t1 | NA | NA |
Sequences
>g6927.t1 Gene=g6927 Length=1458
ATGGAAAGAAATGTTGAAAAAAGTTGGAATGATGAATTATTTGATCCAACACCGATCTGG
AAACGAAGAAGATACTTTGTAGTTTTTATGGCATTTCTTGGACTTTTTAATGTTTATGCA
CTACGTTCAAATTTAAATGTCGCAATAGTGTCTATGACAGATAATCGTACAATTGAACAT
CCAGATAATACAACAACATATGAACAGTATTTTAATTGGAATTCAAAAGAAAAAGGTTAT
GCACTTTCATCATTTTATTATGGTTATCTGTGTACGCAAATTATTGGAGGTGTTATTGCA
CAAAAAACCGGTGGAAGCATCCTATTTGGTTGTGGTATTGGAGTGACTGCAATAATGACT
CTGCTAACACCTTTAGCTGCAAATCTGAGTTTATATGCACTGATTGGTGTACGGGTTATT
GAAGGGCTCTTTGAAGGTGTAACATATTCTGCACTTTATGAAATGTGGTCTAAATGGGCA
CCACCATTTGAAAGGTCAAGAATGGTCGTAGCAGCATTCACTGGAAATTATATAGGGCTT
GTCATTAGCATGCCAGTGAGCGGAATTTTGGCAGCATCAGTAGGATGGGAATGGATATTT
TACGTATTTGGTATAATTGGATGTGTTTGGACAGTATTATGGTTGATATTTATAAGACGA
AGTCCAGCTAGGGATCCATTTATAACAGCGGGTGAAAGAATATACATAGAGCAATCATTA
AATAGACAATCTATGGATAAAGAAGTTAAAATTCCATGGAAAGCTATTTTTAATTCGAGT
GCTGTTTGGGCAATTATTGCTGCACAATTTAGTGAAGGTTGGGGCTTCTTTACTTTGCAA
ACTCAGCTCCCACAGTTCTTAAAAGATGCATTAAATTTTGATATTGCGAAATCTGGAATA
ATTTCGGCATTGCCTTATCTTTGCATGGCTGTAATGTGTCAAATTGCTGGCTATCTTTCT
GACTGGGTACGAATTAAAGGGTATTGGACAACAGGACAAACACGACGATATTTTAATTCA
ATGGCGTTTTTAACACAAATGGCTTGCATGTTACTTGCAGCTTTCTTTCTGCATCCTGTT
TCATCGGTTACATTTATTACGATTGGTGTGGCTATGGCATCATTTGCTTATGCCAGCTTT
TCTGTAAATTATCTAGATATTGCACCACAATTTGCAGGCGTTTTAATGGGGCTTTGCAAC
AGTTTTGCAACAGTCGCAGGAATAATTTCACCTATTTTGACTGGATATATTGTAACTGAT
GCTGATGCAGAACAATGGAAAATAATTTTCTATATTGCTGCTGGAATTTATGTTTTTGGT
TGTGTTATTTATTGGATTTGGGCACAAGGAGAAATTCAACCATGGGCAGTTCAAGAATCG
ATTGAGTTTGAAGATGCTTCTGAAATGCCAAAAATACAAAATGGAATTTCAAATCCTGCA
CTTGATGTAAAGAAATAA
>g6927.t1 Gene=g6927 Length=485
MERNVEKSWNDELFDPTPIWKRRRYFVVFMAFLGLFNVYALRSNLNVAIVSMTDNRTIEH
PDNTTTYEQYFNWNSKEKGYALSSFYYGYLCTQIIGGVIAQKTGGSILFGCGIGVTAIMT
LLTPLAANLSLYALIGVRVIEGLFEGVTYSALYEMWSKWAPPFERSRMVVAAFTGNYIGL
VISMPVSGILAASVGWEWIFYVFGIIGCVWTVLWLIFIRRSPARDPFITAGERIYIEQSL
NRQSMDKEVKIPWKAIFNSSAVWAIIAAQFSEGWGFFTLQTQLPQFLKDALNFDIAKSGI
ISALPYLCMAVMCQIAGYLSDWVRIKGYWTTGQTRRYFNSMAFLTQMACMLLAAFFLHPV
SSVTFITIGVAMASFAYASFSVNYLDIAPQFAGVLMGLCNSFATVAGIISPILTGYIVTD
ADAEQWKIIFYIAAGIYVFGCVIYWIWAQGEIQPWAVQESIEFEDASEMPKIQNGISNPA
LDVKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 32 | g6927.t1 | CDD | cd17318 | MFS_SLC17 | 29 | 448 | 1.40384E-157 |
| 5 | g6927.t1 | Gene3D | G3DSA:1.20.1250.20 | MFS general substrate transporter like domains | 18 | 227 | 4.3E-38 |
| 6 | g6927.t1 | Gene3D | G3DSA:1.20.1250.20 | MFS general substrate transporter like domains | 248 | 453 | 5.0E-35 |
| 2 | g6927.t1 | PANTHER | PTHR11662 | SOLUTE CARRIER FAMILY 17 | 20 | 462 | 5.5E-171 |
| 3 | g6927.t1 | PANTHER | PTHR11662:SF437 | GH23975P | 20 | 462 | 5.5E-171 |
| 1 | g6927.t1 | Pfam | PF07690 | Major Facilitator Superfamily | 32 | 411 | 2.3E-55 |
| 11 | g6927.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 24 | - |
| 24 | g6927.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 25 | 42 | - |
| 18 | g6927.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 43 | 79 | - |
| 25 | g6927.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 80 | 100 | - |
| 12 | g6927.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 101 | 106 | - |
| 29 | g6927.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 107 | 127 | - |
| 15 | g6927.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 128 | 132 | - |
| 30 | g6927.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 133 | 156 | - |
| 10 | g6927.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 157 | 167 | - |
| 21 | g6927.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 168 | 192 | - |
| 19 | g6927.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 193 | 197 | - |
| 27 | g6927.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 198 | 218 | - |
| 13 | g6927.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 219 | 254 | - |
| 20 | g6927.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 255 | 279 | - |
| 17 | g6927.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 280 | 298 | - |
| 31 | g6927.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 299 | 319 | - |
| 9 | g6927.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 320 | 339 | - |
| 23 | g6927.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 340 | 357 | - |
| 16 | g6927.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 358 | 362 | - |
| 22 | g6927.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 363 | 385 | - |
| 8 | g6927.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 386 | 391 | - |
| 28 | g6927.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 392 | 416 | - |
| 14 | g6927.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 417 | 427 | - |
| 26 | g6927.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 428 | 447 | - |
| 7 | g6927.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 448 | 485 | - |
| 45 | g6927.t1 | ProSiteProfiles | PS50850 | Major facilitator superfamily (MFS) profile. | 23 | 452 | 23.096 |
| 4 | g6927.t1 | SUPERFAMILY | SSF103473 | MFS general substrate transporter | 15 | 456 | 5.62E-76 |
| 37 | g6927.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 25 | 42 | - |
| 43 | g6927.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 81 | 100 | - |
| 34 | g6927.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 107 | 129 | - |
| 41 | g6927.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 134 | 156 | - |
| 39 | g6927.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 169 | 191 | - |
| 42 | g6927.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 196 | 218 | - |
| 44 | g6927.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 256 | 278 | - |
| 33 | g6927.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 298 | 320 | - |
| 36 | g6927.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 340 | 357 | - |
| 35 | g6927.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 362 | 384 | - |
| 40 | g6927.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 391 | 413 | - |
| 38 | g6927.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 428 | 447 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055085 | transmembrane transport | BP |
| GO:0022857 | transmembrane transporter activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
